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Biomol. Chem."],"abstract":"<jats:p>\n                    We have designed and developed an unprecedented hydrido-alkynyl-Prins cyclization, using isopropanol as hydride donor. The mechanism involves an alternate alkynyl-Prins cyclization, [1,5]-hydride migration, and SN\n                    <jats:sub>2<\/jats:sub>\n                    \u2032 nucleophilic substitution cascade.\n                  <\/jats:p>","DOI":"10.1039\/d6ob00688d","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T02:23:22Z","timestamp":1780539802000},"page":"5355-5362","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A hydrido-alkynyl-Prins cyclization using isopropanol as a hydride donor: discovery, scope and mechanistic study"],"prefix":"10.1039","volume":"24","author":[{"given":"Gollachinnamola","family":"Ramesh","sequence":"first","affiliation":[{"name":"Department of Chemistry, Indian Institute of Technology Madras, Chennai-600036, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surabhi","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Indian Institute of Technology Madras, Chennai-600036, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8810-1620","authenticated-orcid":false,"given":"Beeraiah","family":"Baire","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Indian Institute of Technology Madras, Chennai-600036, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6OB00688D\/cit1a\/1","doi-asserted-by":"crossref","first-page":"5461","DOI":"10.1021\/jacs.9b00198","volume":"141","author":"Holt","year":"2019","journal-title":"J. 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