{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T11:10:51Z","timestamp":1790334651433,"version":"4.1.0"},"reference-count":29,"publisher":"Royal Society of Chemistry (RSC)","issue":"34","license":[{"start":{"date-parts":[[2027,8,5]],"date-time":"2027-08-05T00:00:00Z","timestamp":1817424000000},"content-version":"am","delay-in-days":581,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["JBR\/2023\/000005"],"award-info":[{"award-number":["JBR\/2023\/000005"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Org. Biomol. Chem."],"abstract":"<jats:p>We report the design and synthesis of a redox-responsive paclitaxel\u2013BODIPY conjugate (PTX-SS-BDP) in which paclitaxel is linked to a BODIPY moiety through a glutathione-cleavable disulfide spacer.<\/jats:p>","DOI":"10.1039\/d6ob00954a","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T06:03:57Z","timestamp":1785909837000},"page":"6979-6985","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reductive microenvironment-activated paclitaxel\u2013BODIPY nanoassemblies for self-reporting drug delivery"],"prefix":"10.1039","volume":"24","author":[{"given":"Deepak","family":"Tayde","sequence":"first","affiliation":[{"name":"CSIR-Central Salt and Marine Chemicals Research Institute, Bhavnagar, Gujarat 364002, India"},{"name":"Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi Ranjan","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, Indian Institute of Science Education and Research, Kolkata, West Bengal 741246, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3666-1743","authenticated-orcid":false,"given":"Amitava","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, Indian Institute of Science Education and Research, Kolkata, West Bengal 741246, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0294-8829","authenticated-orcid":false,"given":"Sumit Kumar","family":"Pramanik","sequence":"additional","affiliation":[{"name":"CSIR-Central Salt and Marine Chemicals Research Institute, Bhavnagar, Gujarat 364002, India"},{"name":"Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6OB00954A\/cit1\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41523-025-00734-x","volume":"11","author":"Komar","year":"2025","journal-title":"npj Breast Cancer"},{"key":"D6OB00954A\/cit2\/1","doi-asserted-by":"crossref","first-page":"105567","DOI":"10.1016\/j.jddst.2024.105567","volume":"95","author":"Kaveh Zenjanab","year":"2024","journal-title":"J. Drug Delivery Sci. Technol."},{"key":"D6OB00954A\/cit3\/1","first-page":"1","volume":"14","author":"Patel","year":"2024","journal-title":"Sci. Rep."},{"key":"D6OB00954A\/cit4\/1","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1038\/sj.bjc.6603772","volume":"96","author":"Berghmans","year":"2007","journal-title":"Br. J. Cancer"},{"key":"D6OB00954A\/cit5\/1","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1021\/jacs.4c11820","volume":"147","author":"Chatterjee","year":"2025","journal-title":"J. Am. Chem. Soc."},{"key":"D6OB00954A\/cit6\/1","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1038\/nrd3253","volume":"9","author":"Dumontet","year":"2010","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D6OB00954A\/cit7\/1","doi-asserted-by":"crossref","first-page":"3039","DOI":"10.1007\/s00018-005-5330-x","volume":"62","author":"Honore","year":"2005","journal-title":"Cell. Mol. Life Sci."},{"key":"D6OB00954A\/cit8\/1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1039\/C3NP70092E","volume":"31","author":"Rohena","year":"2014","journal-title":"Nat. Prod. Rep."},{"key":"D6OB00954A\/cit9\/1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1158\/1535-7163.MCT-13-0791","volume":"13","author":"Mukhtar","year":"2014","journal-title":"Mol. Cancer Ther."},{"key":"D6OB00954A\/cit10\/1","doi-asserted-by":"crossref","first-page":"956","DOI":"10.7150\/thno.38288","volume":"10","author":"Dasgupta","year":"2020","journal-title":"Theranostics"},{"key":"D6OB00954A\/cit11\/1","doi-asserted-by":"crossref","first-page":"37398","DOI":"10.1021\/jacs.5c11249","volume":"147","author":"Bose","year":"2025","journal-title":"J. Am. Chem. Soc."},{"key":"D6OB00954A\/cit12\/1","doi-asserted-by":"crossref","first-page":"2403243","DOI":"10.1002\/adhm.202403243","volume":"14","author":"Sarkar","year":"2025","journal-title":"Adv. Healthcare Mater."},{"key":"D6OB00954A\/cit13\/1","doi-asserted-by":"crossref","first-page":"10393","DOI":"10.1021\/acsnano.3c01064","volume":"17","author":"Kandoth","year":"2023","journal-title":"ACS Nano"},{"key":"D6OB00954A\/cit14\/1","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1039\/D0QM00684J","volume":"5","author":"Sreedharan","year":"2021","journal-title":"Mater. Chem. Front."},{"key":"D6OB00954A\/cit15\/1","doi-asserted-by":"crossref","first-page":"671","DOI":"10.3109\/1354750X.2012.715672","volume":"17","author":"Gamcsik","year":"2012","journal-title":"Biomarkers"},{"key":"D6OB00954A\/cit16\/1","doi-asserted-by":"crossref","first-page":"11718","DOI":"10.1021\/acs.chemrev.9b00379","volume":"119","author":"Singh","year":"2019","journal-title":"Chem. Rev."},{"key":"D6OB00954A\/cit17\/1","doi-asserted-by":"crossref","first-page":"6604","DOI":"10.1039\/c3ob41284a","volume":"11","author":"Das","year":"2013","journal-title":"Org. Biomol. Chem."},{"key":"D6OB00954A\/cit18\/1","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1021\/acs.bioconjchem.6b00324","volume":"27","author":"Pal","year":"2016","journal-title":"Bioconjugate Chem."},{"key":"D6OB00954A\/cit19\/1","doi-asserted-by":"crossref","first-page":"7052","DOI":"10.1021\/acs.macromol.7b01318","volume":"50","author":"Fuoco","year":"2017","journal-title":"Macromolecules"},{"key":"D6OB00954A\/cit20\/1","doi-asserted-by":"crossref","first-page":"2316145","DOI":"10.1002\/adfm.202316145","volume":"34","author":"Song","year":"2024","journal-title":"Adv. Funct. Mater."},{"key":"D6OB00954A\/cit21\/1","doi-asserted-by":"crossref","first-page":"27139","DOI":"10.1021\/acsami.4c03611","volume":"16","author":"Fu","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D6OB00954A\/cit22\/1","doi-asserted-by":"crossref","first-page":"113517","DOI":"10.1016\/j.eurpolymj.2024.113517","volume":"221","author":"Godzina","year":"2024","journal-title":"Eur. Polym. J."},{"key":"D6OB00954A\/cit23\/1","doi-asserted-by":"crossref","first-page":"16932","DOI":"10.1039\/C5CC07450A","volume":"51","author":"Ali","year":"2015","journal-title":"Chem. Commun."},{"key":"D6OB00954A\/cit24\/1","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1039\/c3sc50282a","volume":"4","author":"Suresh","year":"2013","journal-title":"Chem. Sci."},{"key":"D6OB00954A\/cit25\/1","doi-asserted-by":"crossref","first-page":"4854","DOI":"10.1039\/c3dt53056f","volume":"43","author":"Misra","year":"2014","journal-title":"Dalton Trans."},{"key":"D6OB00954A\/cit26\/1","doi-asserted-by":"crossref","first-page":"e1700093","DOI":"10.1002\/hlca.201700093","volume":"100","author":"Prlj","year":"2017","journal-title":"Helv. Chim. Acta"},{"key":"D6OB00954A\/cit27\/1","doi-asserted-by":"crossref","first-page":"11257","DOI":"10.1002\/chem.202101628","volume":"27","author":"Zhang","year":"2021","journal-title":"Chem. \u2013 Eur. J."},{"key":"D6OB00954A\/cit28\/1","unstructured":"Volume of MCF-7 (breast cancer) cell - Human Homo sapiens \u2013 BNID 115154,  https:\/\/bionumbers.hms.harvard.edu\/bionumber.aspx , accessed 15 October 2025"},{"key":"D6OB00954A\/cit29\/1","doi-asserted-by":"publisher","DOI":"10.1515\/1553-3840.1644","volume":"9","author":"Radhika","year":"2012","journal-title":"J. Complementary Integr. Med."}],"updated-by":[{"DOI":"10.1039\/d6ob90117d","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000}}],"container-title":["Organic &amp; Biomolecular Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/OB\/article-pdf\/doi\/10.1039\/D6OB00954A\/0\/D6OB00954A.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T15:21:24Z","timestamp":1788362484000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/OB\/article-lookup\/doi\/10.1039\/D6OB00954A"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":29,"journal-issue":{"issue":"34","published-print":{"date-parts":[[2026,9,2]]}},"URL":"https:\/\/doi.org\/10.1039\/d6ob00954a","relation":{},"ISSN":["1477-0520","1477-0539"],"issn-type":[{"value":"1477-0520","type":"print"},{"value":"1477-0539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}