{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T19:29:21Z","timestamp":1786562961684,"version":"build-2736575974"},"reference-count":37,"publisher":"Royal Society of Chemistry (RSC)","issue":"37","license":[{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"vor","delay-in-days":194,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>\n                    This study presents a dual-precision liposomal platform (Tot-Lip) for acne vulgaris, integrating HA\u2011CD44 targeting and\n                    <jats:italic>C. acnes<\/jats:italic>\n                    lipase\u2011responsive release.\n                  <\/jats:p>","DOI":"10.1039\/d6ra01613h","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:32:53Z","timestamp":1784043173000},"page":"40388-40396","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Totarol loaded lipase-responsive liposomes for anti Gram-positive bacterium infection"],"prefix":"10.1039","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-9041-9867","authenticated-orcid":false,"given":"Ziwu","family":"Zhang","sequence":"first","affiliation":[{"name":"Ke Ying Guangzhou Cosmetics Co., Ltd, Research Institute of Keying Group, 73 Fenghuang South Road, Huadu District, Guangzhou 510800, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Huang","sequence":"additional","affiliation":[{"name":"Ke Ying Guangzhou Cosmetics Co., Ltd, Research Institute of Keying Group, 73 Fenghuang South Road, Huadu District, Guangzhou 510800, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Wu","sequence":"additional","affiliation":[{"name":"Ke Ying Guangzhou Cosmetics Co., Ltd, Research Institute of Keying Group, 73 Fenghuang South Road, Huadu District, Guangzhou 510800, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhao","family":"Xiang","sequence":"additional","affiliation":[{"name":"Ke Ying Guangzhou Cosmetics Co., Ltd, Research Institute of Keying Group, 73 Fenghuang South Road, Huadu District, Guangzhou 510800, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Lin","sequence":"additional","affiliation":[{"name":"Ke Ying Guangzhou Cosmetics Co., Ltd, Research Institute of Keying Group, 73 Fenghuang South Road, Huadu District, Guangzhou 510800, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Ji","sequence":"additional","affiliation":[{"name":"Ke Ying Guangzhou Cosmetics Co., Ltd, Research Institute of Keying Group, 73 Fenghuang South Road, Huadu District, Guangzhou 510800, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6RA01613H\/cit1\/1","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/1471-2334-14-92","volume":"14","author":"Vazquez-Guillamet","year":"2014","journal-title":"BMC Infect. Dis."},{"key":"D6RA01613H\/cit2\/1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1146\/annurev-micro-112123-100908","volume":"78","author":"Chang","year":"2024","journal-title":"Annu. Rev. Microbiol."},{"key":"D6RA01613H\/cit3\/1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/nrmicro.2017.157","volume":"16","author":"Byrd","year":"2018","journal-title":"Nat. Rev. Microbiol."},{"key":"D6RA01613H\/cit4\/1","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1038\/s42003-022-03897-6","volume":"5","author":"Ahle","year":"2022","journal-title":"Commun. Biol."},{"key":"D6RA01613H\/cit5\/1","first-page":"10","author":"Sharma","year":"2025","journal-title":"Curr. Pharm. Biotechnol."},{"key":"D6RA01613H\/cit6\/1","doi-asserted-by":"crossref","first-page":"e242","DOI":"10.1002\/cbdv.202500242","volume":"22","author":"Hussien","year":"2025","journal-title":"Chem. Biodivers."},{"key":"D6RA01613H\/cit7\/1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3390\/md22080347","volume":"22","author":"Liu","year":"2024","journal-title":"Mar. Drugs"},{"key":"D6RA01613H\/cit8\/1","doi-asserted-by":"crossref","first-page":"e20230237","DOI":"10.1590\/0001-3765202420230237","volume":"96","author":"Bandeira","year":"2024","journal-title":"An. Acad. Bras. Cienc."},{"key":"D6RA01613H\/cit9\/1","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1248\/cpb.56.1691","volume":"56","author":"Sato","year":"2008","journal-title":"Chem. Pharm. Bull."},{"key":"D6RA01613H\/cit10\/1","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1139\/cjm-2024-0014","volume":"70","author":"Hyeon","year":"2024","journal-title":"Can. J. Microbiol."},{"key":"D6RA01613H\/cit11\/1","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1002\/adsc.200700005","volume":"349","author":"Ncanana","year":"2007","journal-title":"Adv. Synth. Catal."},{"key":"D6RA01613H\/cit12\/1","doi-asserted-by":"crossref","first-page":"288","DOI":"10.3390\/pharmaceutics12030288","volume":"12","author":"Haider","year":"2020","journal-title":"Pharmaceutics"},{"key":"D6RA01613H\/cit13\/1","doi-asserted-by":"crossref","first-page":"e02847","DOI":"10.1002\/slct.202502847","volume":"10","author":"Shinde","year":"2025","journal-title":"ChemistrySelect"},{"key":"D6RA01613H\/cit14\/1","doi-asserted-by":"crossref","first-page":"113850","DOI":"10.1016\/j.addr.2021.113850","volume":"176","author":"Okeyo","year":"2021","journal-title":"Adv. Drug Delivery Rev."},{"key":"D6RA01613H\/cit15\/1","doi-asserted-by":"crossref","first-page":"e2400031","DOI":"10.1002\/adhm.202400031","volume":"13","author":"Yuan","year":"2024","journal-title":"Adv. Healthcare Mater."},{"key":"D6RA01613H\/cit16\/1","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1080\/17425247.2025.2556013","volume":"22","author":"Mustafa","year":"2025","journal-title":"Expet Opin. Drug Deliv."},{"key":"D6RA01613H\/cit17\/1","doi-asserted-by":"crossref","first-page":"e2410566","DOI":"10.1002\/smll.202410566","volume":"21","author":"Chen","year":"2025","journal-title":"Small"},{"key":"D6RA01613H\/cit18\/1","doi-asserted-by":"crossref","first-page":"e2082434177","DOI":"10.1073\/pnas.2212533119","volume":"119","author":"Goh","year":"2022","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6RA01613H\/cit19\/1","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/1523-1747.ep12259178","volume":"54","author":"Downing","year":"1970","journal-title":"J. Invest. Dermatol."},{"key":"D6RA01613H\/cit20\/1","doi-asserted-by":"crossref","first-page":"4621","DOI":"10.1038\/s41598-025-88697-8","volume":"15","author":"Seo","year":"2025","journal-title":"Sci. Rep."},{"key":"D6RA01613H\/cit21\/1","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.jid.2022.11.012","volume":"143","author":"Tsao","year":"2023","journal-title":"J. Invest. Dermatol."},{"key":"D6RA01613H\/cit22\/1","first-page":"157","volume":"29","author":"Higaki","year":"2003","journal-title":"Drugs Exp. Clin. Res."},{"key":"D6RA01613H\/cit23\/1","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1017\/S1431927610093645","volume":"16","author":"Bello","year":"2010","journal-title":"Microsc. Microanal."},{"key":"D6RA01613H\/cit24\/1","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1128\/jb.89.4.949-953.1965","volume":"89","author":"Shah","year":"1965","journal-title":"J. Bacteriol."},{"issue":"1","key":"D6RA01613H\/cit25\/1","doi-asserted-by":"publisher","first-page":"e00750","DOI":"10.1128\/IAI.00750-19","volume":"88","author":"Dong","year":"2019","journal-title":"Infect. Immun."},{"key":"D6RA01613H\/cit26\/1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/arch.21442","volume":"97","author":"Zhou","year":"2018","journal-title":"Arch. Insect Biochem. Physiol."},{"key":"D6RA01613H\/cit27\/1","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1194\/jlr.D074385","volume":"58","author":"Ham","year":"2017","journal-title":"J. Lipid Res."},{"key":"D6RA01613H\/cit28\/1","doi-asserted-by":"crossref","first-page":"8597","DOI":"10.1002\/chem.202000529","volume":"26","author":"Lou","year":"2020","journal-title":"Chem.\u2013Eur. J."},{"key":"D6RA01613H\/cit29\/1","doi-asserted-by":"crossref","first-page":"104783","DOI":"10.1016\/j.chemphyslip.2019.104783","volume":"223","author":"Li","year":"2019","journal-title":"Chem. Phys. Lipids"},{"key":"D6RA01613H\/cit30\/1","first-page":"e207358","volume":"13","author":"Schultz","year":"2018","journal-title":"PLoS One"},{"key":"D6RA01613H\/cit31\/1","doi-asserted-by":"crossref","first-page":"104631","DOI":"10.1016\/j.jddst.2023.104631","volume":"86","author":"Luo","year":"2023","journal-title":"J. Drug Delivery Sci. Technol."},{"key":"D6RA01613H\/cit32\/1","doi-asserted-by":"crossref","first-page":"134690","DOI":"10.1016\/j.ijbiomac.2024.134690","volume":"278","author":"Barros","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D6RA01613H\/cit33\/1","doi-asserted-by":"crossref","first-page":"100063","DOI":"10.1016\/j.bioflm.2021.100063","volume":"4","author":"Coenye","year":"2021","journal-title":"Biofilm"},{"key":"D6RA01613H\/cit34\/1","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.3389\/fmicb.2019.01284","volume":"10","author":"Gannesen","year":"2019","journal-title":"Front. Microbiol."},{"key":"D6RA01613H\/cit35\/1","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.2147\/DDDT.S105367","volume":"10","author":"Reinbold","year":"2016","journal-title":"Drug Des., Dev. Ther."},{"key":"D6RA01613H\/cit36\/1","first-page":"924","volume":"55","author":"Shi","year":"2018","journal-title":"J. Agric Sci. Food Technol."},{"key":"D6RA01613H\/cit37\/1","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1055\/s-2006-957832","volume":"62","author":"Haraguchi","year":"1996","journal-title":"Planta Med."}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/RA\/article-pdf\/doi\/10.1039\/D6RA01613H\/0\/D6RA01613H.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T18:53:38Z","timestamp":1786560818000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/RA\/article-lookup\/doi\/10.1039\/D6RA01613H"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":37,"journal-issue":{"issue":"37","published-print":{"date-parts":[[2026,8,12]]}},"URL":"https:\/\/doi.org\/10.1039\/d6ra01613h","relation":{},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}