{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:13:55Z","timestamp":1790162035322,"version":"4.1.0"},"reference-count":89,"publisher":"Royal Society of Chemistry (RSC)","issue":"42","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":239,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100010322","name":"Pakistan Academy of Sciences","doi-asserted-by":"publisher","award":["PAS Project No. 111"],"award-info":[{"award-number":["PAS Project No. 111"]}],"id":[{"id":"10.13039\/501100010322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004681","name":"Higher Education Commission, Pakistan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004681","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>Synthesized quinoline-based thiourea molecules were identified as potent inhibitors of \u03b1-amylase, \u03b1-glucosidase, AChE, and BChE, with some compounds outperforming acarbose and donepezil. Compounds were also found as potential antioxidants.<\/jats:p>","DOI":"10.1039\/d6ra03204d","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:34:05Z","timestamp":1787906045000},"page":"50974-51001","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Design and synthesis of quinoline-derived thioureas as potential antihyperglycemic, anti-Alzheimer, and antioxidant agents"],"prefix":"10.1039","volume":"16","author":[{"given":"Faiza","family":"Seraj","sequence":"first","affiliation":[{"name":"H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Maqbool","sequence":"additional","affiliation":[{"name":"H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fayaz","family":"Ali","sequence":"additional","affiliation":[{"name":"H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sridevi","family":"Chigurupati","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Buraydah, 52571, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syeda Sumayya","family":"Tariq","sequence":"additional","affiliation":[{"name":"Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1871-9112","authenticated-orcid":false,"given":"Uzma","family":"Salar","sequence":"additional","affiliation":[{"name":"Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8530-8711","authenticated-orcid":false,"given":"Zaheer","family":"Ul-Haq","sequence":"additional","affiliation":[{"name":"Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasudevan","family":"Mani","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, 51452, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shatha Ghazi","family":"Felemban","sequence":"additional","affiliation":[{"name":"Medical Laboratory Sciences Department-MLS Program, Fakeeh College for Medical Sciences, Fakeeh Care Group, Jeddah, 21461, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9276-2929","authenticated-orcid":false,"given":"Khalid Mohammed","family":"Khan","sequence":"additional","affiliation":[{"name":"H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan"},{"name":"Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P. O. Box 31441, Dammam, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6RA03204D\/cit1\/1","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1080\/17568919.2024.2419359","volume":"16","author":"Seraj","year":"2024","journal-title":"Future Med. Chem."},{"key":"D6RA03204D\/cit2\/1","first-page":"1","author":"Kaul","year":"2012","journal-title":"Adv. Exp. Med. Biol."},{"key":"D6RA03204D\/cit3\/1","doi-asserted-by":"crossref","first-page":"111677","DOI":"10.1016\/j.ejmech.2019.111677","volume":"183","author":"Hameed","year":"2019","journal-title":"Eur. J. Med. Chem."},{"key":"D6RA03204D\/cit4\/1","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.7150\/ijms.10001","volume":"11","author":"Wu","year":"2014","journal-title":"Int. J. Med. Sci."},{"key":"D6RA03204D\/cit5\/1","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1038\/nrneph.2017.138","volume":"13","author":"Smith","year":"2017","journal-title":"Nat. Rev. Nephrol."},{"key":"D6RA03204D\/cit6\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nrdp.2017.16","volume":"3","author":"Katsarou","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"D6RA03204D\/cit7\/1","doi-asserted-by":"crossref","first-page":"889","DOI":"10.4239\/wjd.v5.i6.889","volume":"5","author":"Barbagallo","year":"2014","journal-title":"World J. Diabetes"},{"key":"D6RA03204D\/cit8\/1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.2147\/DMSO.S9089","volume":"3","author":"Badawi","year":"2010","journal-title":"Diabetes, Metab. Syndr. Obes.: Targets Ther."},{"key":"D6RA03204D\/cit9\/1","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1111\/cbdd.13909","volume":"98","author":"Kaur","year":"2021","journal-title":"Chem. Biol. Drug Des."},{"key":"D6RA03204D\/cit10\/1","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1196\/annals.1384.008","volume":"1098","author":"Granger","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"D6RA03204D\/cit11\/1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.beem.2016.06.005","volume":"30","author":"Samson","year":"2016","journal-title":"Best Pract. Res., Clin. Endocrinol. Metab."},{"key":"D6RA03204D\/cit12\/1","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1007\/s11101-021-09773-1","volume":"21","author":"Dirir","year":"2022","journal-title":"Phytochem. Rev."},{"key":"D6RA03204D\/cit13\/1","doi-asserted-by":"crossref","first-page":"729","DOI":"10.7326\/M15-0381","volume":"163","author":"Kelley","year":"2015","journal-title":"Ann. Intern. Med."},{"key":"D6RA03204D\/cit14\/1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.14283\/jpad.2021.23","volume":"8","author":"Porsteinsson","year":"2021","journal-title":"J. Prev. Alzheimers Dis."},{"key":"D6RA03204D\/cit15\/1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.4155\/ppa-2023-0020","volume":"12","author":"Saleem","year":"2023","journal-title":"Pharm. Pat. Anal."},{"key":"D6RA03204D\/cit16\/1","doi-asserted-by":"crossref","first-page":"115522","DOI":"10.1016\/j.bcp.2023.115522","volume":"211","author":"Monteiro","year":"2023","journal-title":"Biochem. Pharmacol."},{"key":"D6RA03204D\/cit17\/1","doi-asserted-by":"crossref","first-page":"4377","DOI":"10.2174\/138161206778792985","volume":"12","author":"Castro","year":"2006","journal-title":"Curr. Pharm. Des."},{"key":"D6RA03204D\/cit18\/1","doi-asserted-by":"crossref","first-page":"4913","DOI":"10.1073\/pnas.83.13.4913","volume":"83","author":"Grundke-Iqbal","year":"1986","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6RA03204D\/cit19\/1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.4161\/cam.3.1.7402","volume":"3","author":"Gella","year":"2009","journal-title":"Cell Adhes. Migr."},{"key":"D6RA03204D\/cit20\/1","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.ejmech.2013.02.014","volume":"63","author":"He","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"D6RA03204D\/cit21\/1","first-page":"155","volume":"69","author":"Ansari","year":"2010","journal-title":"Exp. Neurol."},{"key":"D6RA03204D\/cit22\/1","doi-asserted-by":"crossref","first-page":"4309","DOI":"10.1021\/jm300106z","volume":"55","author":"Chen","year":"2012","journal-title":"J. Med. Chem."},{"key":"D6RA03204D\/cit23\/1","doi-asserted-by":"crossref","first-page":"113320","DOI":"10.1016\/j.ejmech.2021.113320","volume":"216","author":"Srivastava","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"D6RA03204D\/cit24\/1","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1080\/14756366.2019.1644329","volume":"34","author":"Atatreh","year":"2019","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D6RA03204D\/cit25\/1","first-page":"26731","volume":"15","author":"Nordberg","year":"2013","journal-title":"Prim. Care Companion CNS Disord."},{"key":"D6RA03204D\/cit26\/1","doi-asserted-by":"crossref","first-page":"21695","DOI":"10.1038\/s41598-020-78782-5","volume":"10","author":"Heo","year":"2020","journal-title":"Sci. Rep."},{"key":"D6RA03204D\/cit27\/1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1017\/S1041610203008676","volume":"14","author":"Greig","year":"2002","journal-title":"Int. Psychogeriatr."},{"key":"D6RA03204D\/cit28\/1","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1039\/C7MD00199A","volume":"8","author":"Liu","year":"2017","journal-title":"MedChemComm"},{"key":"D6RA03204D\/cit29\/1","doi-asserted-by":"crossref","first-page":"42660","DOI":"10.1039\/C6RA00302H","volume":"6","author":"Kumar","year":"2016","journal-title":"RSC Adv."},{"key":"D6RA03204D\/cit30\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejmech.2010.08.054","volume":"46","author":"Tomassoli","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"D6RA03204D\/cit31\/1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.4103\/0973-7847.70902","volume":"4","author":"Lobo","year":"2010","journal-title":"Pharmacogn. Rev."},{"key":"D6RA03204D\/cit32\/1","doi-asserted-by":"crossref","first-page":"8416763","DOI":"10.1155\/2017\/8416763","volume":"1","author":"Pizzino","year":"2017","journal-title":"Oxid. Med. Cell. Longev."},{"key":"D6RA03204D\/cit33\/1","doi-asserted-by":"crossref","first-page":"117329","DOI":"10.1016\/j.lfs.2020.117329","volume":"244","author":"Ashrafizadeh","year":"2020","journal-title":"Life Sci."},{"key":"D6RA03204D\/cit34\/1","doi-asserted-by":"crossref","first-page":"763","DOI":"10.3233\/JAD-2009-1013","volume":"16","author":"Reddy","year":"2009","journal-title":"J. Alzheimers Dis."},{"key":"D6RA03204D\/cit35\/1","doi-asserted-by":"crossref","first-page":"14450","DOI":"10.3390\/ijms241914450","volume":"24","author":"Veselov","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"D6RA03204D\/cit36\/1","doi-asserted-by":"crossref","first-page":"2400325","DOI":"10.1002\/ardp.202400325","volume":"357","author":"Maqbool","year":"2024","journal-title":"Arch. Pharm."},{"key":"D6RA03204D\/cit37\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jsps.2012.03.002","volume":"21","author":"Marella","year":"2013","journal-title":"Saudi Pharm. J."},{"key":"D6RA03204D\/cit38\/1","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1007\/s00044-023-03121-y","volume":"32","author":"Shehab","year":"2023","journal-title":"Med. Chem. Res."},{"key":"D6RA03204D\/cit39\/1","doi-asserted-by":"crossref","first-page":"18594","DOI":"10.1039\/D2RA02896D","volume":"12","author":"Ajani","year":"2022","journal-title":"RSC Adv."},{"key":"D6RA03204D\/cit40\/1","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.4155\/fmc-2023-0168","volume":"15","author":"Seraj","year":"2023","journal-title":"Future Med. Chem."},{"key":"D6RA03204D\/cit41\/1","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.ejmech.2017.10.046","volume":"143","author":"El Shehry","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"D6RA03204D\/cit42\/1","doi-asserted-by":"crossref","first-page":"102968","DOI":"10.1016\/j.bioorg.2019.102968","volume":"88","author":"Khan","year":"2019","journal-title":"Bioorg. Chem."},{"key":"D6RA03204D\/cit43\/1","doi-asserted-by":"crossref","first-page":"127172","DOI":"10.1016\/j.bmcl.2020.127172","volume":"30","author":"Calvert","year":"2020","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D6RA03204D\/cit44\/1","doi-asserted-by":"crossref","first-page":"e07484","DOI":"10.1016\/j.heliyon.2021.e07484","volume":"7","author":"Velmurugan","year":"2021","journal-title":"Heliyon"},{"key":"D6RA03204D\/cit45\/1","doi-asserted-by":"crossref","first-page":"3495","DOI":"10.1021\/acs.chemrev.0c00922","volume":"121","author":"Porras","year":"2020","journal-title":"Chem. Rev."},{"key":"D6RA03204D\/cit46\/1","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1007\/s10895-023-03416-8","volume":"34","author":"Dey","year":"2024","journal-title":"J. Fluoresc."},{"key":"D6RA03204D\/cit47\/1","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.2174\/1389557520999201214234735","volume":"21","author":"Tabassum","year":"2021","journal-title":"Mini Rev. Med. Chem."},{"key":"D6RA03204D\/cit48\/1","doi-asserted-by":"crossref","first-page":"115458","DOI":"10.1016\/j.ejmech.2023.115458","volume":"256","author":"Ravindar","year":"2023","journal-title":"Eur. J. Med. Chem."},{"key":"D6RA03204D\/cit49\/1","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.ejmech.2017.12.044","volume":"144","author":"Zhang","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"D6RA03204D\/cit50\/1","doi-asserted-by":"crossref","first-page":"653","DOI":"10.2174\/1570193X16666190213105146","volume":"16","author":"Kumari","year":"2019","journal-title":"Mini-Rev. Org. Chem."},{"key":"D6RA03204D\/cit51\/1","doi-asserted-by":"crossref","first-page":"3562","DOI":"10.3390\/molecules18033562","volume":"18","author":"Kocyigit-Kaymakcioglu","year":"2013","journal-title":"Molecules"},{"key":"D6RA03204D\/cit52\/1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/B978-0-12-817030-4.00023-1","volume-title":"Handbook of Electronic Waste Management","author":"Ramanayaka","year":"2020","unstructured":"S.Ramanayaka ,  S.Keerthanan , and  M.Vithanage ,  Handbook of Electronic Waste Management ,  2020 ,  pp. 19\u201354"},{"key":"D6RA03204D\/cit53\/1","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1515\/chem-2020-0139","volume":"18","author":"Naz","year":"2020","journal-title":"Open Chem."},{"key":"D6RA03204D\/cit54\/1","doi-asserted-by":"crossref","first-page":"4506","DOI":"10.3390\/molecules26154506","volume":"26","author":"Rahman","year":"2021","journal-title":"Molecules"},{"key":"D6RA03204D\/cit55\/1","doi-asserted-by":"crossref","first-page":"44212","DOI":"10.1038\/s41598-025-32012-y","volume":"15","author":"Saeed","year":"2025","journal-title":"Sci. Rep."},{"key":"D6RA03204D\/cit56\/1","doi-asserted-by":"crossref","first-page":"135173","DOI":"10.1016\/j.molstruc.2023.135173","volume":"1282","author":"Taha","year":"2023","journal-title":"J. Mol. Struct."},{"key":"D6RA03204D\/cit57\/1","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/slct.201803222","volume":"4","author":"Duarte","year":"2019","journal-title":"ChemistrySelect"},{"key":"D6RA03204D\/cit58\/1","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1007\/s13738-018-01580-4","volume":"16","author":"Kumar","year":"2019","journal-title":"J. Iran. Chem. Soc."},{"key":"D6RA03204D\/cit59\/1","doi-asserted-by":"crossref","first-page":"5521","DOI":"10.1080\/10406638.2021.1939069","volume":"42","author":"Lohitha","year":"2022","journal-title":"Polycyclic Aromat. Compd."},{"key":"D6RA03204D\/cit60\/1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3998\/ark.5550190.0011.b22","volume":"11","author":"Chakrabarty","year":"2010","journal-title":"Arkivoc"},{"key":"D6RA03204D\/cit61\/1","doi-asserted-by":"crossref","first-page":"3166","DOI":"10.1007\/s00044-015-1369-x","volume":"24","author":"Taha","year":"2015","journal-title":"Med. Chem. Res."},{"key":"D6RA03204D\/cit62\/1","doi-asserted-by":"crossref","first-page":"2387415","DOI":"10.1080\/14756366.2024.2387415","volume":"39","author":"Xu","year":"2024","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D6RA03204D\/cit63\/1","doi-asserted-by":"crossref","first-page":"26768","DOI":"10.1039\/C9RA04540F","volume":"9","author":"Ding","year":"2019","journal-title":"RSC Adv."},{"key":"D6RA03204D\/cit64\/1","doi-asserted-by":"crossref","first-page":"3380","DOI":"10.3390\/ijms22073380","volume":"22","author":"Munteanu","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"D6RA03204D\/cit65\/1","doi-asserted-by":"crossref","first-page":"6843","DOI":"10.1074\/jbc.M115.708495","volume":"291","author":"Ram\u00edrez-Escudero","year":"2016","journal-title":"J. Biol. Chem."},{"key":"D6RA03204D\/cit66\/1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ejmech.2018.09.052","volume":"159","author":"Yousuf","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"D6RA03204D\/cit67\/1","doi-asserted-by":"crossref","first-page":"103195","DOI":"10.1016\/j.bioorg.2019.103195","volume":"94","author":"Rafique","year":"2020","journal-title":"Bioorg. Chem."},{"key":"D6RA03204D\/cit68\/1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.2174\/0929867003375191","volume":"7","author":"Sugimoto","year":"2000","journal-title":"Curr. Med. Chem."},{"key":"D6RA03204D\/cit69\/1","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1248\/bpb.18.1145","volume":"18","author":"Nochi","year":"1995","journal-title":"Biol. Pharm. Bull."},{"key":"D6RA03204D\/cit70\/1","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/S0006-3495(91)82138-5","volume":"60","author":"Franke","year":"1991","journal-title":"Biophys. J."},{"key":"D6RA03204D\/cit71\/1","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1007\/s11696-022-02648-5","volume":"77","author":"Haq","year":"2023","journal-title":"Chem. Pap."},{"key":"D6RA03204D\/cit72\/1","doi-asserted-by":"crossref","first-page":"105073","DOI":"10.1016\/j.bioorg.2021.105073","volume":"114","author":"Aroua","year":"2021","journal-title":"Bioorg. Chem."},{"key":"D6RA03204D\/cit73\/1","first-page":"063","volume":"11","author":"Chigurupati","year":"2021","journal-title":"J. Appl. Pharm. Sci."},{"key":"D6RA03204D\/cit74\/1","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3390\/pharmaceutics15020457","volume":"15","author":"Aroua","year":"2023","journal-title":"Pharmaceutics"},{"key":"D6RA03204D\/cit75\/1","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.4155\/fmc-2022-0103","volume":"14","author":"Hameed","year":"2022","journal-title":"Future Med. Chem."},{"key":"D6RA03204D\/cit76\/1","doi-asserted-by":"crossref","first-page":"103651","DOI":"10.1016\/j.arabjc.2021.103651","volume":"15","author":"Saleem","year":"2022","journal-title":"Arab. J. Chem."},{"key":"D6RA03204D\/cit77\/1","first-page":"102","volume":"59","author":"Chigurupati","year":"2021","journal-title":"Indian J. Exp. Biol."},{"key":"D6RA03204D\/cit78\/1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.bioorg.2016.05.002","volume":"67","author":"Chigurupati","year":"2016","journal-title":"Bioorg. Chem."},{"key":"D6RA03204D\/cit79\/1","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s00044-017-2104-6","volume":"27","author":"Chigurupati","year":"2018","journal-title":"Med. Chem. Res."},{"key":"D6RA03204D\/cit80\/1","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1134\/S1068162022060061","volume":"48","author":"Ali","year":"2022","journal-title":"Russ. J. Bioorg. Chem."},{"key":"D6RA03204D\/cit81\/1","doi-asserted-by":"crossref","first-page":"5579","DOI":"10.1016\/j.sjbs.2021.05.072","volume":"28","author":"Chigurupati","year":"2021","journal-title":"Saudi J. Biol. Sci."},{"key":"D6RA03204D\/cit82\/1","doi-asserted-by":"crossref","first-page":"825","DOI":"10.2298\/JSC211106005B","volume":"88","author":"Babatunde","year":"2023","journal-title":"J. Serb. Chem. Soc."},{"key":"D6RA03204D\/cit83\/1","first-page":"325","volume":"25","author":"Sridevi","year":"2009","journal-title":"Orient. J. Chem."},{"key":"D6RA03204D\/cit84\/1","first-page":"775","volume":"27","author":"Chigurupati","year":"2020","journal-title":"Int. Food Res. J."},{"key":"D6RA03204D\/cit85\/1","doi-asserted-by":"crossref","first-page":"22726","DOI":"10.1021\/acsomega.1c03056","volume":"6","author":"Akande","year":"2021","journal-title":"ACS Omega"},{"key":"D6RA03204D\/cit86\/1","doi-asserted-by":"crossref","first-page":"3857","DOI":"10.1007\/s11030-024-10813-z","volume":"29","author":"Egu","year":"2025","journal-title":"Mol. Divers."},{"key":"D6RA03204D\/cit88\/1","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1002\/(SICI)1096-987X(199604)17:5\/6<490::AID-JCC1>3.0.CO;2-P","volume":"17","author":"Halgren","year":"1996","journal-title":"J. Comput. Chem."},{"key":"D6RA03204D\/cit89\/1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0023-6438(95)80008-5","volume":"28","author":"Brand-Williams","year":"1995","journal-title":"LWT\u2013Food Sci. Technol."},{"key":"D6RA03204D\/cit90\/1","first-page":"7167691","volume":"1","author":"Sulimov","year":"2017","journal-title":"Adv. Bioinform."}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/RA\/article-pdf\/doi\/10.1039\/D6RA03204D\/0\/D6RA03204D.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T10:48:43Z","timestamp":1790160523000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/RA\/article-lookup\/doi\/10.1039\/D6RA03204D"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":89,"journal-issue":{"issue":"42","published-print":{"date-parts":[[2026,9,23]]}},"URL":"https:\/\/doi.org\/10.1039\/d6ra03204d","relation":{},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}