{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:59:26Z","timestamp":1790164766332,"version":"4.1.0"},"reference-count":34,"publisher":"Royal Society of Chemistry (RSC)","issue":"42","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":237,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100017531","name":"Medical and Health Research Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2023KY241"],"award-info":[{"award-number":["2023KY241"]}],"id":[{"id":"10.13039\/501100017531","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017531","name":"Medical and Health Research Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2024KY1481"],"award-info":[{"award-number":["2024KY1481"]}],"id":[{"id":"10.13039\/501100017531","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017531","name":"Medical and Health Research Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2025KY1296"],"award-info":[{"award-number":["2025KY1296"]}],"id":[{"id":"10.13039\/501100017531","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007834","name":"Natural Science Foundation of Ningbo Municipality","doi-asserted-by":"publisher","award":["2023J213"],"award-info":[{"award-number":["2023J213"]}],"id":[{"id":"10.13039\/100007834","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004387","name":"Ningbo University","doi-asserted-by":"publisher","award":["JYXM2024122"],"award-info":[{"award-number":["JYXM2024122"]}],"id":[{"id":"10.13039\/501100004387","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004387","name":"Ningbo University","doi-asserted-by":"publisher","award":["JYXM2026028"],"award-info":[{"award-number":["JYXM2026028"]}],"id":[{"id":"10.13039\/501100004387","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>Novel biodegradable PBC-betamethasone film for efficient TM perforation repair.<\/jats:p>","DOI":"10.1039\/d6ra03917k","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T10:19:06Z","timestamp":1787739546000},"page":"50595-50612","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Betamethasone-loaded poly(1,4-butylene carbonate) film: a potential material for repairing tympanic membrane perforations"],"prefix":"10.1039","volume":"16","author":[{"given":"Linrong","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, The Affiliated Lihuili Hospital of Ningbo University, Ningbo 315100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiming","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bio-based Polymeric Materials Technology and Application of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangyu","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, The Affiliated Lihuili Hospital of Ningbo University, Ningbo 315100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaoke","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ningbo No. 2 Hospital, Wenzhou Medical University, Ningbo, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, The Affiliated Lihuili Hospital of Ningbo University, Ningbo 315100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, The Affiliated Lihuili Hospital of Ningbo University, Ningbo 315100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caohong","family":"Chen","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bio-based Polymeric Materials Technology and Application of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinggang","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bio-based Polymeric Materials Technology and Application of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6383-4200","authenticated-orcid":false,"given":"Junjun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Emergency Surgery, Ningbo Hospital of Integrated Traditional Chinese and Western Medicine, Ningbo 315100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6RA03917K\/cit1\/1","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1177\/0003489419901139","volume":"129","author":"Yang","year":"2020","journal-title":"Ann. Otol., Rhinol., Laryngol."},{"key":"D6RA03917K\/cit2\/1","doi-asserted-by":"publisher","first-page":"103408","DOI":"10.1016\/j.amjoto.2022.103408","volume":"43","author":"Zhao","year":"2022","journal-title":"Am. J. Otolaryngol."},{"key":"D6RA03917K\/cit3\/1","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1089\/ten.TEB.2020.0176","volume":"27","author":"Aleemardani","year":"2021","journal-title":"Tissue Eng., Part B"},{"key":"D6RA03917K\/cit4\/1","doi-asserted-by":"publisher","first-page":"032004","DOI":"10.1088\/1748-605X\/abcf5d","volume":"16","author":"Hussain","year":"2021","journal-title":"Biomed. Mater."},{"key":"D6RA03917K\/cit5\/1","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1002\/lary.28914","volume":"131","author":"Ghanad","year":"2021","journal-title":"Laryngoscope"},{"key":"D6RA03917K\/cit6\/1","doi-asserted-by":"publisher","first-page":"110964","DOI":"10.1016\/j.ijporl.2021.110964","volume":"151","author":"Mokoyan","year":"2021","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"D6RA03917K\/cit7\/1","doi-asserted-by":"publisher","first-page":"121430","DOI":"10.1016\/j.biomaterials.2022.121430","volume":"282","author":"Schilling","year":"2022","journal-title":"Biomaterials"},{"key":"D6RA03917K\/cit8\/1","doi-asserted-by":"publisher","first-page":"e2100085","DOI":"10.1002\/mabi.202100085","volume":"21","author":"Amsden","year":"2021","journal-title":"Macromol. Biosci."},{"key":"D6RA03917K\/cit9\/1","doi-asserted-by":"publisher","first-page":"15417","DOI":"10.3390\/ijms242015417","volume":"24","author":"Stickdorn","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"D6RA03917K\/cit10\/1","doi-asserted-by":"publisher","first-page":"e31789","DOI":"10.1016\/j.heliyon.2024.e31789","volume":"10","author":"Lv","year":"2024","journal-title":"Heliyon"},{"key":"D6RA03917K\/cit11\/1","doi-asserted-by":"publisher","first-page":"103408","DOI":"10.1016\/j.amjoto.2024.104258","volume":"43","author":"Wang","year":"2024","journal-title":"Am. J. Otolaryngol."},{"key":"D6RA03917K\/cit12\/1","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1002\/lio2.670","volume":"6","author":"Faramarzi","year":"2021","journal-title":"Laryngoscope Invest. Otolaryngol."},{"key":"D6RA03917K\/cit13\/1","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s00405-002-0494-6","volume":"260","author":"Bahadir","year":"2003","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"D6RA03917K\/cit14\/1","doi-asserted-by":"publisher","first-page":"337","DOI":"10.22038\/ijorl.2019.39914.2343","volume":"32","author":"Barati","year":"2020","journal-title":"Iran. J. Otorhinolaryngol."},{"key":"D6RA03917K\/cit15\/1","doi-asserted-by":"publisher","first-page":"102955","DOI":"10.1016\/j.amjoto.2021.102955","volume":"42","author":"Abdullah","year":"2021","journal-title":"Am. J. Otolaryngol."},{"key":"D6RA03917K\/cit16\/1","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.3390\/ph16091322","volume":"16","author":"Matos","year":"2023","journal-title":"Pharmaceuticals"},{"key":"D6RA03917K\/cit17\/1","doi-asserted-by":"publisher","first-page":"1348172","DOI":"10.3389\/fphar.2024.1348172","volume":"15","author":"Moatti","year":"2024","journal-title":"Front. Pharmacol"},{"key":"D6RA03917K\/cit18\/1","doi-asserted-by":"publisher","first-page":"4725","DOI":"10.3390\/ma14164725","volume":"14","author":"Flak","year":"2021","journal-title":"Materials"},{"key":"D6RA03917K\/cit19\/1","doi-asserted-by":"publisher","first-page":"184","DOI":"10.2174\/156720109787846243","volume":"6","author":"Rafienia","year":"2009","journal-title":"Curr. Drug Delivery"},{"key":"D6RA03917K\/cit20\/1","doi-asserted-by":"publisher","first-page":"2736","DOI":"10.3390\/polym12112736","volume":"12","author":"Hirai","year":"2020","journal-title":"Polymers"},{"key":"D6RA03917K\/cit21\/1","doi-asserted-by":"publisher","first-page":"1614","DOI":"10.1021\/acs.langmuir.6b04143","volume":"33","author":"Gallardo","year":"2017","journal-title":"Langmuir"},{"key":"D6RA03917K\/cit22\/1","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1002\/jbm.a.32119","volume":"90","author":"Kim","year":"2009","journal-title":"J. Biomed. Mater. Res., Part A"},{"key":"D6RA03917K\/cit23\/1","doi-asserted-by":"publisher","first-page":"118480","DOI":"10.1002\/jbm.a.32119","volume":"567","author":"Ajmal","year":"2019","journal-title":"Int. J. Pharm."},{"key":"D6RA03917K\/cit24\/1","doi-asserted-by":"publisher","first-page":"292","DOI":"10.3390\/polym13020292","volume":"13","author":"Arbeiter","year":"2021","journal-title":"Polymers"},{"key":"D6RA03917K\/cit25\/1","doi-asserted-by":"publisher","first-page":"S153","DOI":"10.1055\/S-0039-1686513","volume":"98","author":"Stoppe","year":"2019","journal-title":"Laryngo-Rhino-Otologie"},{"key":"D6RA03917K\/cit26\/1","doi-asserted-by":"publisher","first-page":"5722","DOI":"10.1021\/acs.biomac.3c00691","volume":"24","author":"Hu","year":"2023","journal-title":"Biomacromolecules"},{"key":"D6RA03917K\/cit27\/1","doi-asserted-by":"publisher","first-page":"2288","DOI":"10.1039\/c9bm00440h","volume":"7","author":"Fukushima","year":"2019","journal-title":"Biomater. Sci."},{"key":"D6RA03917K\/cit28\/1","doi-asserted-by":"publisher","first-page":"5722","DOI":"10.1021\/acs.biomac.3c00691","volume":"24","author":"Hu","year":"2023","journal-title":"Biomacromolecules"},{"key":"D6RA03917K\/cit29\/1","doi-asserted-by":"publisher","first-page":"145478","DOI":"10.1016\/j.ijbiomac.2025.145478","volume":"320","author":"Xiao","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"D6RA03917K\/cit30\/1","doi-asserted-by":"publisher","first-page":"107868","DOI":"10.1016\/j.cmpb.2023.107868","volume":"243","author":"Wang","year":"2024","journal-title":"Comput. Methods Programs Biomed."},{"key":"D6RA03917K\/cit31\/1","doi-asserted-by":"publisher","first-page":"248","DOI":"10.3390\/polym16020248","volume":"16","author":"Svistushkin","year":"2024","journal-title":"Polymers"},{"key":"D6RA03917K\/cit32\/1","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1177\/0194599820938345","volume":"164","author":"Yao","year":"2021","journal-title":"Otolaryngol., Head Neck Surg."},{"key":"D6RA03917K\/cit33\/1","doi-asserted-by":"publisher","first-page":"e497","DOI":"10.1097\/MAO.0000000000003468","volume":"43","author":"Shahal","year":"2022","journal-title":"Otol. Neurotol."},{"key":"D6RA03917K\/cit34\/1","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.actbio.2024.09.019","volume":"188","author":"Lee","year":"2024","journal-title":"Acta Biomater."}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/RA\/article-pdf\/doi\/10.1039\/D6RA03917K\/0\/D6RA03917K.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:00:50Z","timestamp":1790161250000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/RA\/article-lookup\/doi\/10.1039\/D6RA03917K"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":34,"journal-issue":{"issue":"42","published-print":{"date-parts":[[2026,9,23]]}},"URL":"https:\/\/doi.org\/10.1039\/d6ra03917k","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D6RA03917K\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA03917K\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA03917K\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA03917K\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA03917K\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA03917K\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA03917K\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA03917K\/v3\/decision1","asserted-by":"object"}]},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}