{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:01:02Z","timestamp":1791392462157,"version":"4.3.3"},"reference-count":46,"publisher":"Royal Society of Chemistry (RSC)","issue":"44","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":263,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100008758","name":"Council of Science and Technology, U.P.","doi-asserted-by":"publisher","award":["ID: 4102"],"award-info":[{"award-number":["ID: 4102"]}],"id":[{"id":"10.13039\/501100008758","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002742","name":"Banaras Hindu University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002742","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001501","name":"University Grants Commission","doi-asserted-by":"publisher","award":["211610077377"],"award-info":[{"award-number":["211610077377"]}],"id":[{"id":"10.13039\/501100001501","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001501","name":"University Grants Commission","doi-asserted-by":"publisher","award":["221610005833"],"award-info":[{"award-number":["221610005833"]}],"id":[{"id":"10.13039\/501100001501","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>Identification of putative serum biomarkers associated with the asymptomatic stage of bancroftian filariasis utilizing biochemical characterisation combined with untargeted metabolomics.<\/jats:p>","DOI":"10.1039\/d6ra05988k","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T06:45:23Z","timestamp":1789973123000},"page":"55882-55901","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Haematological and biochemical profiling combined with HRAMS-based metabolomics reveals the potential biomarkers of\n                    <i>Wuchereria bancrofti<\/i>\n                    asymptomatic infections: towards early interventions and diagnostics"],"prefix":"10.1039","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7632-3527","authenticated-orcid":false,"given":"Tripti","family":"Singh","sequence":"first","affiliation":[{"name":"Dept of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, U.P., India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8470-8352","authenticated-orcid":false,"given":"Shivani","family":"Sharma","sequence":"additional","affiliation":[{"name":"Dept of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, U.P., India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0088-324X","authenticated-orcid":false,"given":"Sunil","family":"Kumar","sequence":"additional","affiliation":[{"name":"Dept of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, U.P., India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Medical Health and Family Welfare, Malaria and Vector-Borne Disease, Filaria Control Unit, Varanasi, UP, 221005, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7251-3097","authenticated-orcid":false,"given":"HariOm","family":"Singh","sequence":"additional","affiliation":[{"name":"BSL-4 Laboratory, National Institute of Virology (NIV), Pune, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3254-7257","authenticated-orcid":false,"given":"Anchal","family":"Singh","sequence":"additional","affiliation":[{"name":"Dept of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, U.P., India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6RA05988K\/cit1\/1","doi-asserted-by":"crossref","first-page":"22542","DOI":"10.1039\/D2RA03287B","volume":"12","author":"Kumar","year":"2022","journal-title":"RSC Adv."},{"key":"D6RA05988K\/cit2\/1","unstructured":"Lymphatic Filariasis (Elephantiasis) ,  https:\/\/www.who.int\/health-topics\/lymphatic-filariasis#tab=tab_1 , accessed 13-08-2026, 2026"},{"key":"D6RA05988K\/cit3\/1","doi-asserted-by":"crossref","first-page":"e1186","DOI":"10.1016\/S2214-109X(20)30286-2","volume":"8","author":"Cromwell","year":"2020","journal-title":"Lancet Global Health"},{"key":"D6RA05988K\/cit4\/1","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1093\/cid\/ciz671","volume":"70","author":"Mathew","year":"2020","journal-title":"Clin. Infect. Dis."},{"key":"D6RA05988K\/cit5\/1","doi-asserted-by":"crossref","first-page":"5893","DOI":"10.1039\/D3RA08702F","volume":"14","author":"Mishra","year":"2024","journal-title":"RSC Adv."},{"key":"D6RA05988K\/cit6\/1","first-page":"23","volume-title":"Tropical Medicine and Infectious Disease","volume":"10","author":"Graves","year":"2025","unstructured":"P. M.Graves ,  J. L.Scott ,  A.Berg Soto ,  A. Y.Widi ,  M.Whittaker ,  C. L.Lau  and  K. Y.Won ,  Tropical Medicine and Infectious Disease ,  2025 , vol.  10 ,  p. 23"},{"key":"D6RA05988K\/cit7\/1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1093\/clinids\/5.1.148","volume":"5","author":"Chernin","year":"1983","journal-title":"Rev. Infect. Dis."},{"key":"D6RA05988K\/cit8\/1","doi-asserted-by":"crossref","first-page":"208","DOI":"10.4103\/0972-9062.166256","volume":"52","author":"Khan","year":"2015","journal-title":"J. Vector Borne Dis."},{"key":"D6RA05988K\/cit9\/1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1098\/rspb.1967.0079","volume":"169","author":"Hawking","year":"1967","journal-title":"Proc. R. Soc. London, Ser. B"},{"key":"D6RA05988K\/cit10\/1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3390\/immuno5040057","volume":"5","author":"Singh","year":"2025","journal-title":"Immuno"},{"key":"D6RA05988K\/cit11\/1","first-page":"75","volume":"43","author":"Rawlins","year":"1994","journal-title":"West Indian Med. J."},{"key":"D6RA05988K\/cit12\/1","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1186\/s12879-015-1317-x","volume":"15","author":"Gounoue-Kamkumo","year":"2015","journal-title":"BMC Infect. Dis."},{"key":"D6RA05988K\/cit13\/1","doi-asserted-by":"crossref","first-page":"594687","DOI":"10.1155\/2010\/594687","volume":"2010","author":"Joseph","year":"2010","journal-title":"J. Parasitol. Res."},{"key":"D6RA05988K\/cit14\/1","doi-asserted-by":"crossref","first-page":"106278","DOI":"10.1016\/j.actatropica.2021.106278","volume":"227","author":"Djuardi","year":"2022","journal-title":"Acta Trop."},{"key":"D6RA05988K\/cit15\/1","doi-asserted-by":"crossref","first-page":"910177","DOI":"10.3389\/fcimb.2022.910177","volume":"12","author":"Chienwichai","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"D6RA05988K\/cit16\/1","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1186\/s12879-024-10272-9","volume":"24","author":"Kumar","year":"2024","journal-title":"BMC Infect. Dis."},{"key":"D6RA05988K\/cit17\/1","doi-asserted-by":"crossref","first-page":"e0270635","DOI":"10.1371\/journal.pone.0270635","volume":"17","author":"Kumar","year":"2022","journal-title":"PLoS One"},{"key":"D6RA05988K\/cit18\/1","doi-asserted-by":"crossref","first-page":"113641","DOI":"10.1016\/j.biopha.2022.113641","volume":"155","author":"Zhang","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"D6RA05988K\/cit19\/1","doi-asserted-by":"crossref","first-page":"e14175","DOI":"10.1371\/journal.pone.0014175","volume":"5","author":"Thysell","year":"2010","journal-title":"PLoS One"},{"key":"D6RA05988K\/cit20\/1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s11306-005-4810-1","volume":"1","author":"Rozen","year":"2005","journal-title":"Metabolomics"},{"key":"D6RA05988K\/cit21\/1","doi-asserted-by":"crossref","first-page":"120178","DOI":"10.1016\/j.jep.2025.120178","volume":"352","author":"Zhang","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"D6RA05988K\/cit22\/1","doi-asserted-by":"crossref","first-page":"156568","DOI":"10.1016\/j.metabol.2026.156568","author":"Chen","year":"2026","journal-title":"Metabolism"},{"key":"D6RA05988K\/cit23\/1","doi-asserted-by":"crossref","first-page":"1617207","DOI":"10.3389\/fonc.2025.1617207","volume":"15","author":"Hua","year":"2025","journal-title":"Front. Oncol."},{"key":"D6RA05988K\/cit24\/1","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1186\/s13071-024-06599-6","volume":"17","author":"Wu","year":"2024","journal-title":"Parasites Vectors"},{"key":"D6RA05988K\/cit25\/1","doi-asserted-by":"crossref","first-page":"e0011119","DOI":"10.1371\/journal.pntd.0011119","volume":"17","author":"Chienwichai","year":"2023","journal-title":"PLoS Neglected Trop. Dis."},{"key":"D6RA05988K\/cit26\/1","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.3389\/fmicb.2020.01517","volume":"11","author":"Huang","year":"2020","journal-title":"Front. Microbiol."},{"key":"D6RA05988K\/cit27\/1","doi-asserted-by":"crossref","first-page":"e0005631","DOI":"10.1371\/journal.pntd.0005631","volume":"11","author":"Kar","year":"2017","journal-title":"PLoS Neglected Trop. Dis."},{"key":"D6RA05988K\/cit28\/1","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/S2222-1808(16)61113-1","volume":"6","author":"Mandal","year":"2016","journal-title":"Asian Pac. J. Trop. Dis."},{"key":"D6RA05988K\/cit29\/1","doi-asserted-by":"crossref","first-page":"116031","DOI":"10.1016\/j.biopha.2023.116031","volume":"170","author":"Fu","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"D6RA05988K\/cit30\/1","doi-asserted-by":"crossref","first-page":"13572","DOI":"10.1039\/D5RA09094F","volume":"16","author":"Wang","year":"2026","journal-title":"RSC Adv."},{"key":"D6RA05988K\/cit31\/1","doi-asserted-by":"crossref","first-page":"902494","DOI":"10.3389\/fimmu.2022.902494","volume":"13","author":"Miyake","year":"2022","journal-title":"Front. Immunol."},{"key":"D6RA05988K\/cit32\/1","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/978-1-0716-0696-4_9","volume-title":"Basophils and Mast Cells: Methods and Protocols","author":"Borzova","year":"2020","unstructured":"E.Borzova , in  Basophils and Mast Cells: Methods and Protocols ,  Springer ,  2020 ,  pp. 109\u2013124"},{"key":"D6RA05988K\/cit33\/1","first-page":"801","volume-title":"Williams hematology","author":"Galli","year":"2005","unstructured":"S. J.Galli ,  D. D.Metcalfe ,  D.Arber  and  A.Dvorak ,  Williams hematology ,  2005 ,  pp. 801\u2013816"},{"key":"D6RA05988K\/cit34\/1","doi-asserted-by":"crossref","first-page":"7426","DOI":"10.4049\/jimmunol.0903864","volume":"185","author":"Torrero","year":"2010","journal-title":"J. Immunol."},{"key":"D6RA05988K\/cit35\/1","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.0954-6820.1963.tb07918.x","volume":"174","author":"Juhlin","year":"1963","journal-title":"Acta Med. Scand."},{"key":"D6RA05988K\/cit36\/1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1097\/MPG.0b013e3181a96489","volume":"50","author":"Lima","year":"2010","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"D6RA05988K\/cit37\/1","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.neuint.2007.08.022","volume":"52","author":"Schumacher","year":"2008","journal-title":"Neurochem. Int."},{"key":"D6RA05988K\/cit38\/1","doi-asserted-by":"crossref","first-page":"967","DOI":"10.3390\/antiox10060967","volume":"10","author":"Ten\u00f3rio","year":"2021","journal-title":"Antioxidants"},{"key":"D6RA05988K\/cit39\/1","doi-asserted-by":"crossref","first-page":"12079","DOI":"10.3390\/ijms232012079","volume":"23","author":"Spick","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"D6RA05988K\/cit40\/1","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1186\/s12967-022-03717-9","volume":"20","author":"Li","year":"2022","journal-title":"J. Transl. Med."},{"key":"D6RA05988K\/cit41\/1","doi-asserted-by":"crossref","first-page":"101165","DOI":"10.1016\/j.plipres.2022.101165","volume":"86","author":"Dyall","year":"2022","journal-title":"Prog. Lipid Res."},{"key":"D6RA05988K\/cit42\/1","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/0014-4894(90)90076-O","volume":"71","author":"Liu","year":"1990","journal-title":"Exp. Parasitol."},{"key":"D6RA05988K\/cit43\/1","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.tcb.2024.01.011","volume":"34","author":"Jang","year":"2024","journal-title":"Trends Cell Biol."},{"key":"D6RA05988K\/cit44\/1","doi-asserted-by":"crossref","first-page":"1166S","DOI":"10.3945\/ajcn.112.034637","volume":"96","author":"Ross","year":"2012","journal-title":"Am. J. Clin. Nutr."},{"key":"D6RA05988K\/cit45\/1","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S1471-4906(01)02154-8","volume":"23","author":"Harris","year":"2002","journal-title":"Trends Immunol."},{"key":"D6RA05988K\/cit46\/1","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1002\/eji.202048909","volume":"51","author":"Oyesola","year":"2021","journal-title":"Eur. J. Immunol."}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/RA\/article-pdf\/doi\/10.1039\/D6RA05988K\/0\/D6RA05988K.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:42:10Z","timestamp":1791391330000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/RA\/article-lookup\/doi\/10.1039\/D6RA05988K"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":46,"journal-issue":{"issue":"44","published-print":{"date-parts":[[2026,10,7]]}},"URL":"https:\/\/doi.org\/10.1039\/d6ra05988k","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D6RA05988K\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA05988K\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA05988K\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA05988K\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA05988K\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6RA05988K\/v1\/decision1","asserted-by":"object"}]},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}