{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T12:35:07Z","timestamp":1793277307392,"version":"4.5.0"},"reference-count":49,"publisher":"Royal Society of Chemistry (RSC)","issue":"47","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":286,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100005010","name":"Associazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","award":["IG2025"],"award-info":[{"award-number":["IG2025"]}],"id":[{"id":"10.13039\/501100005010","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004271","name":"Sapienza Universit\u00e0 di Roma","doi-asserted-by":"publisher","award":["RM124190F0042AFB"],"award-info":[{"award-number":["RM124190F0042AFB"]}],"id":[{"id":"10.13039\/501100004271","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004271","name":"Sapienza Universit\u00e0 di Roma","doi-asserted-by":"publisher","award":["RM125199C2EC82C7"],"award-info":[{"award-number":["RM125199C2EC82C7"]}],"id":[{"id":"10.13039\/501100004271","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004271","name":"Sapienza Universit\u00e0 di Roma","doi-asserted-by":"publisher","award":["AR22419078894D"],"award-info":[{"award-number":["AR22419078894D"]}],"id":[{"id":"10.13039\/501100004271","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>Small-sized hydrophilic gold nanoparticles (AuNPs) loaded with trastuzumab: interfacial interactions and photothermal study.<\/jats:p>","DOI":"10.1039\/d6ra07147c","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T15:57:40Z","timestamp":1791993460000},"page":"62953-62961","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mixed-thiol functionalised gold nanoparticles for trastuzumab delivery: chemical interaction and photothermal therapeutic potential"],"prefix":"10.1039","volume":"16","author":[{"given":"Tommaso A.","family":"Salamone","sequence":"first","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, 00189, Italy"},{"name":"Department of Chemistry, Sapienza University of Rome, Rome, 00185, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosanna","family":"Mosetti","sequence":"additional","affiliation":[{"name":"Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, 00161 Rome, Italy"},{"name":"Department of Physics, Sapienza University of Rome, Rome, 00185, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"D'Arco","sequence":"additional","affiliation":[{"name":"Department of Physics, Sapienza University of Rome, Rome, 00185, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Lupi","sequence":"additional","affiliation":[{"name":"Department of Physics, Sapienza University of Rome, Rome, 00185, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Petronella","sequence":"additional","affiliation":[{"name":"National Research Council, Department of Chemical Sciences and Materials Technologies, Institute of Crystallography, Montelibretti, 00010, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Avitabile","sequence":"additional","affiliation":[{"name":"Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, 04100, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flaminia","family":"Pompeo","sequence":"additional","affiliation":[{"name":"Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, 04100, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2183-6910","authenticated-orcid":false,"given":"Luciano","family":"De Sio","sequence":"additional","affiliation":[{"name":"Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, 04100, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Marotta","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, 00189, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stella","family":"Mrmi\u0107","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, 00189, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Pennacchi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Sapienza University of Rome, Rome, 00185, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5549-9406","authenticated-orcid":false,"given":"Sara","family":"Cerra","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Sapienza University of Rome, Rome, 00185, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souren","family":"Grigorian","sequence":"additional","affiliation":[{"name":"Institute of Physics, University of Siegen, Siegen, D-57068, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Paulus","sequence":"additional","affiliation":[{"name":"Fakult\u00e4t Physik\/DELTA, Technische Universit\u00e4t Dortmund, 44221 Dortmund, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Alimandi","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, 00189, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pankaj","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine, Sapienza University of Rome, Rome, 00161, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni","family":"Anastasiadou","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, 00189, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5172-0636","authenticated-orcid":false,"given":"Ilaria","family":"Fratoddi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Sapienza University of Rome, Rome, 00185, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6RA07147C\/cit1\/1","doi-asserted-by":"publisher","first-page":"33999","DOI":"10.1021\/acsomega.5c03162","volume":"10","author":"Sati","year":"2025","journal-title":"ACS Omega"},{"key":"D6RA07147C\/cit2\/1","doi-asserted-by":"publisher","first-page":"100194","DOI":"10.1016\/j.onano.2023.100194","volume":"15","author":"Singh","year":"2024","journal-title":"OpenNano"},{"key":"D6RA07147C\/cit3\/1","doi-asserted-by":"publisher","first-page":"3255","DOI":"10.1039\/D5NA00111K","volume":"7","author":"Abdussalam-Mohammed","year":"2025","journal-title":"Nanoscale Adv."},{"key":"D6RA07147C\/cit4\/1","doi-asserted-by":"publisher","first-page":"6865","DOI":"10.1021\/acs.chemmater.3c01162","volume":"35","author":"Porcheron","year":"2023","journal-title":"Chem. Mater."},{"key":"D6RA07147C\/cit5\/1","doi-asserted-by":"publisher","first-page":"128553","DOI":"10.1016\/j.molliq.2025.128553","volume":"437","author":"Pis\u00e1r\u010dik","year":"2025","journal-title":"J. Mol. Liq."},{"key":"D6RA07147C\/cit6\/1","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1111\/php.13010","volume":"94","author":"Bard","year":"2018","journal-title":"Photochem. Photobiol."},{"key":"D6RA07147C\/cit7\/1","doi-asserted-by":"publisher","first-page":"115481","DOI":"10.1016\/j.addr.2024.115481","volume":"216","author":"Dykman","year":"2025","journal-title":"Adv. Drug Delivery Rev."},{"key":"D6RA07147C\/cit8\/1","doi-asserted-by":"publisher","first-page":"2100282","DOI":"10.1002\/ppsc.202100282","volume":"39","author":"Venditti","year":"2022","journal-title":"Part. Part. Syst. Charact."},{"key":"D6RA07147C\/cit9\/1","doi-asserted-by":"publisher","first-page":"4713","DOI":"10.1038\/s41598-022-08185-1","volume":"12","author":"Chaudhari","year":"2022","journal-title":"Sci. Rep."},{"key":"D6RA07147C\/cit10\/1","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.addr.2020.06.005","volume":"157","author":"Fang","year":"2020","journal-title":"Adv. Drug Delivery Rev."},{"key":"D6RA07147C\/cit11\/1","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.addr.2012.05.012","volume":"65","author":"Doane","year":"2013","journal-title":"Adv. Drug Delivery Rev."},{"key":"D6RA07147C\/cit12\/1","doi-asserted-by":"publisher","first-page":"2349","DOI":"10.3390\/pharmaceutics15092349","volume":"15","author":"Kumar","year":"2023","journal-title":"Pharmaceutics"},{"key":"D6RA07147C\/cit13\/1","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1016\/j.xphs.2022.12.001","volume":"112","author":"Fitzgerald","year":"2023","journal-title":"J. Pharm. Sci."},{"key":"D6RA07147C\/cit14\/1","doi-asserted-by":"publisher","first-page":"319","DOI":"10.3390\/pharmaceutics15020319","volume":"15","author":"Pontico","year":"2023","journal-title":"Pharmaceutics"},{"key":"D6RA07147C\/cit15\/1","doi-asserted-by":"publisher","first-page":"213272","DOI":"10.1016\/j.bioadv.2022.213272","volume":"145","author":"Vischio","year":"2023","journal-title":"Biomater. Adv."},{"key":"D6RA07147C\/cit16\/1","doi-asserted-by":"publisher","first-page":"3900","DOI":"10.1021\/am400590m","volume":"5","author":"Niikura","year":"2013","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D6RA07147C\/cit17\/1","doi-asserted-by":"publisher","first-page":"6395","DOI":"10.1021\/nn1016346","volume":"4","author":"Poon","year":"2010","journal-title":"ACS Nano"},{"key":"D6RA07147C\/cit18\/1","doi-asserted-by":"publisher","first-page":"e58604","DOI":"10.1371\/journal.pone.0058604","volume":"8","author":"Heinemann","year":"2013","journal-title":"PLoS One"},{"key":"D6RA07147C\/cit19\/1","doi-asserted-by":"publisher","first-page":"787","DOI":"10.3390\/ijms24010787","volume":"24","author":"Namiot","year":"2023","journal-title":"IJMS"},{"key":"D6RA07147C\/cit20\/1","doi-asserted-by":"publisher","first-page":"359","DOI":"10.3390\/vaccines9040359","volume":"9","author":"Thi","year":"2021","journal-title":"Vaccines"},{"key":"D6RA07147C\/cit21\/1","doi-asserted-by":"publisher","first-page":"101559","DOI":"10.1016\/j.rechem.2024.101559","volume":"8","author":"Hossain","year":"2024","journal-title":"Results Chem."},{"key":"D6RA07147C\/cit22\/1","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1186\/s12951-022-01650-z","volume":"20","author":"Sharma","year":"2022","journal-title":"J. Nanobiotechnol."},{"key":"D6RA07147C\/cit23\/1","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.jcis.2023.06.078","volume":"649","author":"Salamone","year":"2023","journal-title":"J. Colloid Interface Sci."},{"key":"D6RA07147C\/cit24\/1","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s12645-025-00330-5","volume":"16","author":"Salamone","year":"2025","journal-title":"Cancer Nanotechnol."},{"key":"D6RA07147C\/cit25\/1","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1039\/D1TB02288A","volume":"10","author":"Yang","year":"2022","journal-title":"J. Mater. Chem. B"},{"key":"D6RA07147C\/cit26\/1","doi-asserted-by":"publisher","first-page":"2400823","DOI":"10.1002\/advs.202400823","volume":"11","author":"Mancini","year":"2024","journal-title":"Adv. Sci."},{"key":"D6RA07147C\/cit27\/1","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s00249-025-01782-8","volume":"55","author":"Mosetti","year":"2025","journal-title":"Eur. Biophys. J."},{"key":"D6RA07147C\/cit28\/1","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1002\/jrs.1238","volume":"35","author":"Long","year":"2004","journal-title":"J. Raman Spectrosc."},{"key":"D6RA07147C\/cit29\/1","doi-asserted-by":"publisher","DOI":"10.1002\/0470011149","volume-title":"Infrared Spectroscopy: Fundamentals and Applications","author":"Stuart","year":"2004","unstructured":"B. H.Stuart ,  Infrared Spectroscopy: Fundamentals and Applications ,  Wiley , 1st edn,  2004 ,  10.1002\/0470011149"},{"key":"D6RA07147C\/cit30\/1","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1038\/nprot.2015.024","volume":"10","author":"Yang","year":"2015","journal-title":"Nat. Protoc."},{"key":"D6RA07147C\/cit31\/1","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.3390\/nano11051103","volume":"11","author":"Piccirilli","year":"2021","journal-title":"Nanomaterials"},{"key":"D6RA07147C\/cit32\/1","doi-asserted-by":"publisher","first-page":"012031","DOI":"10.1088\/1742-6596\/2380\/1\/012031","volume":"2380","author":"Dargasz","year":"2022","journal-title":"J. Phys.: Conf. Ser."},{"key":"D6RA07147C\/cit33\/1","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.3390\/nano10071307","volume":"10","author":"Knights","year":"2020","journal-title":"Nanomaterials"},{"key":"D6RA07147C\/cit34\/1","doi-asserted-by":"publisher","first-page":"3055","DOI":"10.1002\/adma.201204623","volume":"25","author":"Wang","year":"2013","journal-title":"Adv. Mater."},{"key":"D6RA07147C\/cit35\/1","doi-asserted-by":"publisher","first-page":"2546","DOI":"10.3390\/jcm14082546","volume":"14","author":"Zawodny","year":"2025","journal-title":"J. Clin. Med."},{"key":"D6RA07147C\/cit36\/1","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1007\/s10103-025-04519-3","volume":"40","author":"Haji Mohammadi","year":"2025","journal-title":"Lasers Med. Sci."},{"issue":"6","key":"D6RA07147C\/cit37\/1","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1002\/lsm.22793","volume":"50","author":"Xing","year":"2018","journal-title":"Lasers Surg. Med."},{"key":"D6RA07147C\/cit38\/1","doi-asserted-by":"publisher","first-page":"44","DOI":"10.3390\/cosmetics10020044","volume":"10","author":"Cannarozzo","year":"2023","journal-title":"Cosmetics"},{"key":"D6RA07147C\/cit39\/1","doi-asserted-by":"publisher","first-page":"27073","DOI":"10.1021\/jp409067h","volume":"117","author":"Jiang","year":"2013","journal-title":"J. Phys. Chem. C"},{"key":"D6RA07147C\/cit40\/1","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1039\/C8AN01181H","volume":"144","author":"Nilam","year":"2019","journal-title":"Analyst"},{"key":"D6RA07147C\/cit41\/1","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1021\/nn306024a","volume":"7","author":"Hinterwirth","year":"2013","journal-title":"ACS Nano"},{"key":"D6RA07147C\/cit42\/1","doi-asserted-by":"publisher","first-page":"084701","DOI":"10.1063\/5.0078457","volume":"156","author":"Lombard","year":"2022","journal-title":"J. Chem. Phys."},{"key":"D6RA07147C\/cit43\/1","doi-asserted-by":"publisher","first-page":"034036","DOI":"10.1103\/PhysRevApplied.13.034036","volume":"13","author":"Alkurdi","year":"2020","journal-title":"Phys. Rev. Appl."},{"key":"D6RA07147C\/cit44\/1","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.1021\/nn506379m","volume":"9","author":"Park","year":"2015","journal-title":"ACS Nano"},{"key":"D6RA07147C\/cit45\/1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1007\/s10967-019-06450-8","volume":"320","author":"Sterjova","year":"2019","journal-title":"J. Radioanal. Nucl. Chem."},{"key":"D6RA07147C\/cit46\/1","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/j.bbabio.2007.06.004","volume":"1767","author":"Barth","year":"2007","journal-title":"Biochim. Biophys. Acta, Bioenerg."},{"key":"D6RA07147C\/cit47\/1","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.aca.2017.07.045","volume":"990","author":"Bibikova","year":"2017","journal-title":"Anal. Chim. Acta"},{"key":"D6RA07147C\/cit48\/1","doi-asserted-by":"publisher","first-page":"220","DOI":"10.2174\/138920113805219322","volume":"14","author":"Pabari","year":"2013","journal-title":"Curr. Pharm. Biotechnol."},{"key":"D6RA07147C\/cit49\/1","doi-asserted-by":"publisher","first-page":"8253","DOI":"10.1021\/acsomega.8b00591","volume":"3","author":"Tripathi","year":"2018","journal-title":"ACS Omega"}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/RA\/article-pdf\/doi\/10.1039\/D6RA07147C\/0\/D6RA07147C.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T12:03:38Z","timestamp":1793275418000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/RA\/article-lookup\/doi\/10.1039\/D6RA07147C"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":49,"journal-issue":{"issue":"47","published-print":{"date-parts":[[2026,10,29]]}},"URL":"https:\/\/doi.org\/10.1039\/d6ra07147c","relation":{},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}