{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T10:53:03Z","timestamp":1790938383402,"version":"4.1.0"},"reference-count":74,"publisher":"Royal Society of Chemistry (RSC)","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":266,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003977","name":"Israel Science Foundation","doi-asserted-by":"publisher","award":["1805\/22"],"award-info":[{"award-number":["1805\/22"]}],"id":[{"id":"10.13039\/501100003977","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Sci."],"abstract":"<jats:p>A new molecular mechanism explains how phosphorylation and acidosis act together to drive Tau aggregation. Ser352 phosphorylation forms Tau condensates at pH 7.1, while a pH drop triggers their irreversible transition into amyloid filaments.<\/jats:p>","DOI":"10.1039\/d6sc04370d","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:22:33Z","timestamp":1790238153000},"update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Site-specific phosphorylation of Ser352 drives aggregation of Tau R4 under acidosis conditions"],"prefix":"10.1039","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6169-9059","authenticated-orcid":false,"given":"Shachar Guy","family":"Bressler","sequence":"first","affiliation":[{"name":"The Institute of Chemistry, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, 91904, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmia","family":"Blacher","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Ben-Gurion University of the Negev, P.O. Box 653, Be'er Sheva 8410501, Israel"},{"name":"Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, Be\u00e9r-Sheva 8410501, Israel"},{"name":"The School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Be\u00e9r-Sheva 8410501, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0272-0047","authenticated-orcid":false,"given":"Karina Abramov","family":"Harpaz","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Ben-Gurion University of the Negev, P.O. Box 653, Be'er Sheva 8410501, Israel"},{"name":"Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, Be\u00e9r-Sheva 8410501, Israel"},{"name":"The School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Be\u00e9r-Sheva 8410501, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Grunhaus","sequence":"additional","affiliation":[{"name":"The Institute of Chemistry, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, 91904, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1807-2972","authenticated-orcid":false,"given":"Stefan G. D.","family":"R\u00fcdiger","sequence":"additional","affiliation":[{"name":"Protein Chemistry of Disease, Department of Chemistry, Utrecht University, Padualaan 8, 3584CH, Utrecht, The Netherlands"},{"name":"Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan, 8, 3584CH Utrecht, The Netherlands"},{"name":"Science for Life, Utrecht University, Padualaan 8, 3584CH Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1038-8104","authenticated-orcid":false,"given":"Mattan","family":"Hurevich","sequence":"additional","affiliation":[{"name":"The Institute of Chemistry, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, 91904, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah E.","family":"Shalev","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Engineering, Azrieli College of Engineering Jerusalem, Jerusalem 91035, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1163-9745","authenticated-orcid":false,"given":"Yifat","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Ben-Gurion University of the Negev, P.O. Box 653, Be'er Sheva 8410501, Israel"},{"name":"Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, Be\u00e9r-Sheva 8410501, Israel"},{"name":"The School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Be\u00e9r-Sheva 8410501, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1592-1278","authenticated-orcid":false,"given":"Assaf","family":"Friedler","sequence":"additional","affiliation":[{"name":"The Institute of Chemistry, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, 91904, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6SC04370D\/cit1\/1","doi-asserted-by":"crossref","first-page":"975","DOI":"10.3233\/JAD-160612","volume":"57","author":"Rajmohan","year":"2017","journal-title":"J. Alzheimer's Dis."},{"key":"D6SC04370D\/cit2\/1","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/s41580-024-00753-9","volume":"25","author":"Parra Bravo","year":"2024","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"D6SC04370D\/cit3\/1","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/s41593-022-01084-8","volume":"25","author":"Lee","year":"2022","journal-title":"Nat. Neurosci."},{"key":"D6SC04370D\/cit4\/1","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1007\/s00109-003-0464-5","volume":"81","author":"Stefani","year":"2003","journal-title":"J. Mol. Med."},{"key":"D6SC04370D\/cit5\/1","doi-asserted-by":"crossref","first-page":"17495","DOI":"10.1074\/jbc.M112.446070","volume":"288","author":"Basurto-Islas","year":"2013","journal-title":"J. Biol. Chem."},{"key":"D6SC04370D\/cit6\/1","doi-asserted-by":"crossref","first-page":"8762","DOI":"10.1038\/ncomms9762","volume":"6","author":"Zhang","year":"2015","journal-title":"Nat. Commun."},{"key":"D6SC04370D\/cit7\/1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.neurobiolaging.2020.12.007","volume":"101","author":"Decker","year":"2021","journal-title":"Neurobiol. Aging"},{"key":"D6SC04370D\/cit8\/1","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1111\/j.1471-4159.1990.tb04948.x","volume":"55","author":"Yates","year":"1990","journal-title":"J. Neurochem."},{"key":"D6SC04370D\/cit9\/1","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.neurobiolaging.2019.11.012","volume":"87","author":"Lyros","year":"2020","journal-title":"Neurobiol. Aging"},{"key":"D6SC04370D\/cit10\/1","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1186\/s12974-016-0747-8","volume":"13","author":"Tyrtyshnaia","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"D6SC04370D\/cit11\/1","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1365-2567.2009.03225.x","volume":"129","author":"Amor","year":"2010","journal-title":"Immunology"},{"key":"D6SC04370D\/cit12\/1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1113\/jphysiol.1988.sp016961","volume":"396","author":"Balestrino","year":"1988","journal-title":"J. Physiol."},{"key":"D6SC04370D\/cit13\/1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0022-2836(02)00775-1","volume":"322","author":"Hoyer","year":"2002","journal-title":"J. Mol. Biol."},{"key":"D6SC04370D\/cit14\/1","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/s42004-022-00786-1","volume":"5","author":"Wang","year":"2022","journal-title":"Commun. Chem."},{"key":"D6SC04370D\/cit15\/1","volume-title":"Structure of the nonhelical filament\nof the Alzheimer's disease tau core","volume":"120","author":"Duan","year":"2023","unstructured":"P.Duan ,  A. J.Dregni ,  N. E.Mammeri  and  M.Hong ,  Structure of the nonhelical filament\nof the Alzheimer's disease tau core ,  Proceedings of the National Academy of Sciences ,  2023 , vol.  120 , 120, p.  e2310067120"},{"key":"D6SC04370D\/cit16\/1","doi-asserted-by":"crossref","first-page":"e98049","DOI":"10.15252\/embj.201798049","volume":"37","author":"Wegmann","year":"2018","journal-title":"EMBO J."},{"key":"D6SC04370D\/cit17\/1","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1016\/j.cell.2012.02.022","volume":"148","author":"Eisenberg","year":"2012","journal-title":"Cell"},{"key":"D6SC04370D\/cit18\/1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/nrm3810","volume":"15","author":"Knowles","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"D6SC04370D\/cit19\/1","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1038\/s41467-022-30461-x","volume":"13","author":"Meng","year":"2022","journal-title":"Nat. Commun."},{"key":"D6SC04370D\/cit20\/1","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.tcb.2022.01.011","volume":"32","author":"Boyko","year":"2022","journal-title":"Trends Cell Biol."},{"key":"D6SC04370D\/cit21\/1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/s41467-017-00480-0","volume":"8","author":"Ambadipudi","year":"2017","journal-title":"Nat. Commun."},{"key":"D6SC04370D\/cit22\/1","doi-asserted-by":"crossref","first-page":"9284","DOI":"10.1039\/C9OB01874C","volume":"17","author":"Samarasimhareddy","year":"2019","journal-title":"Org. Biomol. Chem."},{"key":"D6SC04370D\/cit23\/1","doi-asserted-by":"crossref","first-page":"6478","DOI":"10.3390\/ijms24076478","volume":"24","author":"Bressler","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"D6SC04370D\/cit24\/1","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1002\/anie.201805238","volume":"58","author":"Ellmer","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"D6SC04370D\/cit25\/1","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1007\/s00702-004-0221-0","volume":"112","author":"Gong","year":"2005","journal-title":"J. Neural Transm."},{"key":"D6SC04370D\/cit26\/1","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1016\/j.cell.2020.10.029","volume":"183","author":"Wesseling","year":"2020","journal-title":"Cell"},{"key":"D6SC04370D\/cit27\/1","doi-asserted-by":"crossref","first-page":"6912","DOI":"10.1039\/D5OB00885A","volume":"23","author":"Bressler","year":"2025","journal-title":"Org. Biomol. Chem."},{"key":"D6SC04370D\/cit28\/1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nature23002","volume":"547","author":"Fitzpatrick","year":"2017","journal-title":"Nature"},{"key":"D6SC04370D\/cit29\/1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1042\/BST20250137","volume":"54","author":"Bressler","year":"2026","journal-title":"Biochem. Soc. Trans."},{"key":"D6SC04370D\/cit30\/1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ab.2005.05.038","volume":"343","author":"Xie","year":"2005","journal-title":"Anal. Biochem."},{"key":"D6SC04370D\/cit31\/1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1399-3011.1994.tb00160.x","volume":"44","author":"Hoffmann","year":"1994","journal-title":"Int. J. Pept. Protein Res."},{"key":"D6SC04370D\/cit32\/1","doi-asserted-by":"crossref","first-page":"5825","DOI":"10.1021\/bi00266a016","volume":"21","author":"Vogel","year":"1982","journal-title":"Biochemistry"},{"key":"D6SC04370D\/cit33\/1","doi-asserted-by":"crossref","first-page":"11054","DOI":"10.1074\/jbc.AC119.009198","volume":"294","author":"Boyko","year":"2019","journal-title":"J. Biol. Chem."},{"key":"D6SC04370D\/cit34\/1","doi-asserted-by":"crossref","first-page":"eabh1448","DOI":"10.1126\/sciadv.abh1448","volume":"7","author":"Meisl","year":"2021","journal-title":"Sci. Adv."},{"key":"D6SC04370D\/cit35\/1","doi-asserted-by":"crossref","first-page":"4707","DOI":"10.1016\/S0021-9258(17)30069-8","volume":"254","author":"Otvos","year":"1979","journal-title":"J. Biol. Chem."},{"key":"D6SC04370D\/cit36\/1","first-page":"411","volume":"3","author":"Zatina","year":"1986","journal-title":"J. Vasc. Surg."},{"key":"D6SC04370D\/cit37\/1","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1073\/pnas.78.4.2125","volume":"78","author":"Gillies","year":"1981","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6SC04370D\/cit38\/1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/pro.19","volume":"18","author":"Grimsley","year":"2009","journal-title":"Protein Sci."},{"key":"D6SC04370D\/cit39\/1","doi-asserted-by":"crossref","first-page":"7276","DOI":"10.1016\/S0021-9258(19)43389-9","volume":"248","author":"Moon","year":"1973","journal-title":"J. Biol. Chem."},{"key":"D6SC04370D\/cit40\/1","doi-asserted-by":"publisher","DOI":"10.1007\/s00249-026-01850-7","author":"Pantoja-Uceda","year":"2026","journal-title":"Eur. Biophys. J."},{"key":"D6SC04370D\/cit41\/1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/s41586-023-06788-w","volume":"625","author":"L\u00f6vestam","year":"2024","journal-title":"Nature"},{"issue":"41","key":"D6SC04370D\/cit42\/1","first-page":"e108882","volume":"41","author":"Hochmair","year":"2022","journal-title":"EMBO J."},{"key":"D6SC04370D\/cit43\/1","doi-asserted-by":"crossref","first-page":"e2111696118","DOI":"10.1073\/pnas.2111696118","volume":"118","author":"Tesei","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6SC04370D\/cit44\/1","doi-asserted-by":"crossref","first-page":"e43584","DOI":"10.7554\/eLife.43584","volume":"8","author":"Zhang","year":"2019","journal-title":"eLife"},{"key":"D6SC04370D\/cit45\/1","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/s42003-023-04847-6","volume":"6","author":"El Mammeri","year":"2023","journal-title":"Commun. Biol."},{"key":"D6SC04370D\/cit46\/1","volume-title":"Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation","volume":"119","author":"Abskharon","year":"2022","unstructured":"R.Abskharon ,  M. R.Sawaya ,  D. R.Boyer ,  Q.Cao ,  B. A.Nguyen ,  D.Cascio  and  D. S.Eisenberg ,  Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation ,  Proceedings of the National Academy of Sciences ,  2022 , vol.  119 , 119, p.  e2119952119"},{"key":"D6SC04370D\/cit47\/1","doi-asserted-by":"crossref","first-page":"166731","DOI":"10.1016\/j.jmb.2020.166731","volume":"433","author":"Lin","year":"2021","journal-title":"J. Mol. Biol."},{"key":"D6SC04370D\/cit48\/1","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1002\/pro.4101","volume":"30","author":"Najafi","year":"2021","journal-title":"Protein Sci."},{"key":"D6SC04370D\/cit49\/1","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1021\/acschemneuro.9b00627","volume":"11","author":"Lin","year":"2020","journal-title":"ACS Chem. Neurosci."},{"key":"D6SC04370D\/cit50\/1","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1002\/pro.4093","volume":"30","author":"Rai","year":"2021","journal-title":"Protein Sci."},{"key":"D6SC04370D\/cit51\/1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/s41593-024-01829-7","volume":"28","author":"Watamura","year":"2025","journal-title":"Nat. Neurosci."},{"key":"D6SC04370D\/cit52\/1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s00401-025-02967-3","volume":"150","author":"Le","year":"2025","journal-title":"Acta Neuropathol."},{"key":"D6SC04370D\/cit53\/1","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1021\/acs.oprd.2c00164","volume":"26","author":"Grunhaus","year":"2022","journal-title":"Org. Process Res. Dev."},{"key":"D6SC04370D\/cit54\/1","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1063\/1.432450","volume":"64","author":"Aue","year":"1976","journal-title":"J. Chem. Phys."},{"issue":"65","key":"D6SC04370D\/cit55\/1","first-page":"355","volume":"1985","author":"Bax","year":"1969","journal-title":"J. Magn. Reson."},{"key":"D6SC04370D\/cit56\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-291X(80)90695-6","volume":"95","author":"Kumar","year":"1980","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"D6SC04370D\/cit57\/1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1006\/jmre.1998.1405","volume":"132","author":"Liu","year":"1998","journal-title":"J. Magn. Reson."},{"key":"D6SC04370D\/cit58\/1","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1093\/bioinformatics\/btu830","volume":"31","author":"Lee","year":"2014","journal-title":"Bioinformatics"},{"key":"D6SC04370D\/cit59\/1","volume-title":"NMR of proteins and nucleic acids","author":"W\u00fcthrich","year":"1986","unstructured":"K.W\u00fcthrich ,  NMR of proteins and nucleic acids ,  Wiley ,  New York ,  1986"},{"key":"D6SC04370D\/cit60\/1","first-page":"14128","volume-title":"Hollow core of Alzheimer's A\u03b242 amyloid observed by cryoEM is relevant at physiological pH","volume":"107","author":"Miller","year":"2010","unstructured":"Y.Miller ,  B.Ma ,  C.-J.Tsai  and  R.Nussinov ,  Hollow core of Alzheimer's A\u03b242 amyloid observed by cryoEM is relevant at physiological pH ,  Proceedings of the National Academy of Sciences ,  2010 ,  107 ,  pp. 14128\u201314133"},{"key":"D6SC04370D\/cit61\/1","volume-title":"CRC handbook of chemistry and physics","author":"Rumble","year":"2017","unstructured":"J.Rumble ,  CRC handbook of chemistry and physics ,  CRC press ,  Boca Raton, FL , plus edition,  2017"},{"key":"D6SC04370D\/cit62\/1","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1002\/prot.20879","volume":"63","author":"Porter","year":"2006","journal-title":"Proteins: Struct., Funct., Bioinf."},{"key":"D6SC04370D\/cit63\/1","doi-asserted-by":"crossref","first-page":"106591","DOI":"10.1016\/j.bpc.2021.106591","volume":"274","author":"Mishra","year":"2021","journal-title":"Biophys. Chem."},{"key":"D6SC04370D\/cit64\/1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jmb.2009.03.039","volume":"389","author":"Harms","year":"2009","journal-title":"J. Mol. Biol."},{"key":"D6SC04370D\/cit65\/1","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1006\/jcph.1999.6201","volume":"151","author":"Kal\u00e9","year":"1999","journal-title":"J. Comput. Phys."},{"key":"D6SC04370D\/cit66\/1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/nmeth.4067","volume":"14","author":"Huang","year":"2017","journal-title":"Nat. Methods"},{"key":"D6SC04370D\/cit67\/1","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1063\/1.445869","volume":"79","author":"Jorgensen","year":"1983","journal-title":"J. Chem. Phys."},{"key":"D6SC04370D\/cit68\/1","doi-asserted-by":"crossref","first-page":"8910","DOI":"10.1063\/1.481505","volume":"112","author":"Mahoney","year":"2000","journal-title":"J. Chem. Phys."},{"key":"D6SC04370D\/cit69\/1","doi-asserted-by":"crossref","first-page":"4613","DOI":"10.1063\/1.470648","volume":"103","author":"Feller","year":"1995","journal-title":"J. Chem. Phys."},{"key":"D6SC04370D\/cit70\/1","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1016\/S0006-3495(95)80126-8","volume":"69","author":"Tu","year":"1995","journal-title":"Biophys. J."},{"key":"D6SC04370D\/cit71\/1","doi-asserted-by":"crossref","first-page":"10089","DOI":"10.1063\/1.464397","volume":"98","author":"Darden","year":"1993","journal-title":"J. Chem. Phys."},{"key":"D6SC04370D\/cit72\/1","doi-asserted-by":"crossref","first-page":"8577","DOI":"10.1063\/1.470117","volume":"103","author":"Essmann","year":"1995","journal-title":"J. Chem. Phys."},{"key":"D6SC04370D\/cit73\/1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0021-9991(77)90098-5","volume":"23","author":"Ryckaert","year":"1977","journal-title":"J. Comput. Phys."},{"key":"D6SC04370D\/cit74\/1","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1002\/bip.360221211","volume":"22","author":"Kabsch","year":"1983","journal-title":"Biopolymers"}],"container-title":["Chemical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/SC\/article-pdf\/doi\/10.1039\/D6SC04370D\/0\/D6SC04370D.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:53:46Z","timestamp":1790934826000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/SC\/article-lookup\/doi\/10.1039\/D6SC04370D"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":74,"URL":"https:\/\/doi.org\/10.1039\/d6sc04370d","relation":{},"ISSN":["2041-6520","2041-6539"],"issn-type":[{"value":"2041-6520","type":"print"},{"value":"2041-6539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}