{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T17:09:17Z","timestamp":1784135357447,"version":"3.55.0"},"reference-count":45,"publisher":"Royal Society of Chemistry (RSC)","issue":"27","license":[{"start":{"date-parts":[[2027,6,18]],"date-time":"2027-06-18T00:00:00Z","timestamp":1813276800000},"content-version":"am","delay-in-days":533,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100007301","name":"Kunming University of Science and Technology","doi-asserted-by":"publisher","award":["KKZ3202503083"],"award-info":[{"award-number":["KKZ3202503083"]}],"id":[{"id":"10.13039\/501100007301","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003996","name":"Kunming Medical University","doi-asserted-by":"publisher","award":["202501AY070001-150"],"award-info":[{"award-number":["202501AY070001-150"]}],"id":[{"id":"10.13039\/501100003996","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005273","name":"Natural Science Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["202501CF070180"],"award-info":[{"award-number":["202501CF070180"]}],"id":[{"id":"10.13039\/501100005273","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["J. Mater. Chem. B"],"abstract":"<jats:p>\n                    A dissolving microneedle (CEGP MNs) patch was fabricated using chitosan oligosaccharide (COS), gallic acid-modified \u03b5-poly-\n                    <jats:sc>l<\/jats:sc>\n                    -lysine (EPL\u2013GA) and polyvinyl alcohol (PVA) for acne therapy.\n                  <\/jats:p>","DOI":"10.1039\/d6tb00953k","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T06:04:13Z","timestamp":1781762653000},"page":"8580-8592","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dissolving microneedles loaded with chitosan oligosaccharides and gallic acid-modified \u03b5-poly-\n                    <scp>l<\/scp>\n                    -lysine for the combined antibacterial and anti-inflammatory therapy of acne vulgaris"],"prefix":"10.1039","volume":"14","author":[{"given":"Yan","family":"Du","sequence":"first","affiliation":[{"name":"Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Suining Central Hospital, Suining, 629000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genmeng","family":"Yang","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Drug Addiction Medicine, School of Forensic Medicine, Kunming Medical University, Kunming, 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruike","family":"Xu","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Drug Addiction Medicine, School of Forensic Medicine, Kunming Medical University, Kunming, 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqing","family":"Lin","sequence":"additional","affiliation":[{"name":"Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuo","family":"Wang","sequence":"additional","affiliation":[{"name":"Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yurong","family":"Sun","sequence":"additional","affiliation":[{"name":"Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongqiang","family":"Gao","sequence":"additional","affiliation":[{"name":"Hepatic Surgery, Affiliated Calmette Hospital of Kunming Medical University, Kunming, 650504, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuangpin","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Rehabilitation, Kunming Medical University, Kunming, 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6783-3461","authenticated-orcid":false,"given":"Hailei","family":"Wang","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital, Kunming Medical University, Kunming, 650118, China"},{"name":"Hepatic Surgery, Affiliated Calmette Hospital of Kunming Medical University, Kunming, 650504, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6TB00953K\/cit1\/1","doi-asserted-by":"crossref","first-page":"6913","DOI":"10.1111\/jocd.15352","volume":"21","author":"Tai","year":"2022","journal-title":"J. Cosmet. Dermatol."},{"key":"D6TB00953K\/cit2\/1","doi-asserted-by":"crossref","first-page":"eadf0854","DOI":"10.1126\/sciadv.adf0854","volume":"9","author":"Xiang","year":"2023","journal-title":"Adv. Sci."},{"key":"D6TB00953K\/cit3\/1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jmst.2024.12.099","volume":"233","author":"Zheng","year":"2025","journal-title":"J. Mater. Sci. Technol."},{"key":"D6TB00953K\/cit4\/1","doi-asserted-by":"crossref","first-page":"21595","DOI":"10.1021\/acsami.4c01790","volume":"16","author":"Wang","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D6TB00953K\/cit5\/1","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.3390\/nano10061095","volume":"10","author":"Hsiao","year":"2020","journal-title":"Nanomaterials"},{"key":"D6TB00953K\/cit6\/1","doi-asserted-by":"crossref","first-page":"112639","DOI":"10.1016\/j.matdes.2024.112639","volume":"238","author":"Zhang","year":"2024","journal-title":"Mater. Des."},{"key":"D6TB00953K\/cit7\/1","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1039\/D3BM01551C","volume":"12","author":"Wang","year":"2024","journal-title":"Biomater. Sci."},{"key":"D6TB00953K\/cit8\/1","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1021\/acsmaterialslett.3c01317","volume":"6","author":"Xue","year":"2024","journal-title":"Acs Mater. Lett."},{"key":"D6TB00953K\/cit9\/1","doi-asserted-by":"crossref","first-page":"103667","DOI":"10.1016\/j.jddst.2022.103667","volume":"75","author":"Xing","year":"2022","journal-title":"J. Drug Delivery Sci. Technol."},{"key":"D6TB00953K\/cit10\/1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.actbio.2020.08.023","volume":"115","author":"Zhang","year":"2020","journal-title":"Acta Biomater."},{"key":"D6TB00953K\/cit11\/1","doi-asserted-by":"crossref","first-page":"143480","DOI":"10.1016\/j.ijbiomac.2025.143480","volume":"310","author":"Li","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"D6TB00953K\/cit12\/1","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1021\/acsabm.3c01295","volume":"7","author":"Yu","year":"2024","journal-title":"ACS Appl. Bio Mater."},{"key":"D6TB00953K\/cit13\/1","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.ijbiomac.2019.01.192","volume":"129","author":"Naveed","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"D6TB00953K\/cit14\/1","doi-asserted-by":"crossref","first-page":"115221","DOI":"10.1016\/j.colsurfb.2025.115221","volume":"258","author":"Xu","year":"2026","journal-title":"Colloids Surf., B"},{"key":"D6TB00953K\/cit15\/1","doi-asserted-by":"crossref","first-page":"123102","DOI":"10.1016\/j.carbpol.2024.123102","volume":"351","author":"Lv","year":"2025","journal-title":"Carbohydr. Polym."},{"key":"D6TB00953K\/cit16\/1","doi-asserted-by":"crossref","first-page":"121546","DOI":"10.1016\/j.carbpol.2023.121546","volume":"324","author":"Yamabhai","year":"2024","journal-title":"Carbohydr. Polym."},{"key":"D6TB00953K\/cit17\/1","first-page":"260","volume":"32","author":"Yang","year":"2024","journal-title":"Bioact. Mater."},{"key":"D6TB00953K\/cit18\/1","doi-asserted-by":"crossref","first-page":"130461","DOI":"10.1016\/j.ijbiomac.2024.130461","volume":"264","author":"Shi","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D6TB00953K\/cit19\/1","doi-asserted-by":"crossref","first-page":"580593","DOI":"10.3389\/fimmu.2020.580593","volume":"11","author":"Lin","year":"2020","journal-title":"Front. Immunol."},{"key":"D6TB00953K\/cit20\/1","doi-asserted-by":"crossref","first-page":"113022","DOI":"10.1016\/j.eurpolymj.2024.113022","volume":"211","author":"Khalil","year":"2024","journal-title":"Eur. Polym. J."},{"key":"D6TB00953K\/cit21\/1","doi-asserted-by":"crossref","first-page":"3644","DOI":"10.1007\/s11694-023-01881-0","volume":"17","author":"Ermis","year":"2023","journal-title":"J. Food Meas. Charact."},{"key":"D6TB00953K\/cit22\/1","doi-asserted-by":"crossref","first-page":"2400958","DOI":"10.1002\/adhm.202400958","volume":"13","author":"Wu","year":"2024","journal-title":"Adv. Healthcare Mater."},{"key":"D6TB00953K\/cit23\/1","doi-asserted-by":"crossref","first-page":"2009442","DOI":"10.1002\/adfm.202009442","volume":"31","author":"Zhao","year":"2021","journal-title":"Adv. Funct. Mater."},{"key":"D6TB00953K\/cit24\/1","doi-asserted-by":"crossref","first-page":"160946","DOI":"10.1016\/j.cej.2025.160946","volume":"508","author":"Liu","year":"2025","journal-title":"Chem. Eng. J."},{"key":"D6TB00953K\/cit25\/1","doi-asserted-by":"crossref","first-page":"2414339","DOI":"10.1002\/advs.202414339","volume":"12","author":"Liu","year":"2025","journal-title":"Adv. Sci."},{"key":"D6TB00953K\/cit26\/1","doi-asserted-by":"crossref","first-page":"128629","DOI":"10.1016\/j.ijbiomac.2023.128629","volume":"257","author":"Li","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D6TB00953K\/cit27\/1","doi-asserted-by":"crossref","first-page":"124577","DOI":"10.1016\/j.carbpol.2025.124577","volume":"373","author":"Wang","year":"2026","journal-title":"Carbohydr. Polym."},{"key":"D6TB00953K\/cit28\/1","doi-asserted-by":"crossref","first-page":"2001196","DOI":"10.1002\/adfm.202001196","volume":"30","author":"Cheng","year":"2020","journal-title":"Adv. Funct. Mater."},{"key":"D6TB00953K\/cit29\/1","doi-asserted-by":"crossref","first-page":"135722","DOI":"10.1016\/j.ijbiomac.2024.135722","volume":"280","author":"Du","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D6TB00953K\/cit30\/1","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1111\/jocd.16279","volume":"23","author":"Zhou","year":"2024","journal-title":"J. Cosmet. Dermatol."},{"key":"D6TB00953K\/cit31\/1","doi-asserted-by":"crossref","first-page":"109496","DOI":"10.1016\/j.carres.2025.109496","volume":"553","author":"Khainskaya","year":"2025","journal-title":"Carbohydr. Res."},{"key":"D6TB00953K\/cit32\/1","doi-asserted-by":"crossref","first-page":"3159","DOI":"10.1038\/s41467-023-38597-0","volume":"14","author":"Li","year":"2023","journal-title":"Nat. Commun."},{"key":"D6TB00953K\/cit33\/1","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/s41551-018-0337-4","volume":"3","author":"Li","year":"2019","journal-title":"Nat. Biomed. Eng."},{"key":"D6TB00953K\/cit34\/1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ijpharm.2014.05.042","volume":"472","author":"Larraneta","year":"2014","journal-title":"Int. J. Pharm."},{"key":"D6TB00953K\/cit35\/1","doi-asserted-by":"crossref","first-page":"114797","DOI":"10.1016\/j.colsurfb.2025.114797","volume":"254","author":"Wang","year":"2025","journal-title":"Colloids Surf., B"},{"key":"D6TB00953K\/cit36\/1","doi-asserted-by":"crossref","first-page":"107557","DOI":"10.1016\/j.intimp.2021.107557","volume":"96","author":"Lim","year":"2021","journal-title":"Int. Immunopharmacol."},{"key":"D6TB00953K\/cit37\/1","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.1039\/C5FO00550G","volume":"6","author":"Huang","year":"2015","journal-title":"Food Funct."},{"key":"D6TB00953K\/cit38\/1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.tim.2023.06.010","volume":"32","author":"Tikhomirova","year":"2024","journal-title":"Trends Microbiol."},{"key":"D6TB00953K\/cit39\/1","doi-asserted-by":"crossref","first-page":"10064","DOI":"10.1073\/pnas.1901730116","volume":"116","author":"Hong","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6TB00953K\/cit40\/1","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1038\/s42003-024-07219-w","volume":"7","author":"Hunt","year":"2024","journal-title":"Commun. Biol."},{"key":"D6TB00953K\/cit41\/1","doi-asserted-by":"crossref","first-page":"2401369","DOI":"10.1002\/adma.202401369","volume":"36","author":"Zhao","year":"2024","journal-title":"Adv. Mater."},{"key":"D6TB00953K\/cit42\/1","doi-asserted-by":"crossref","first-page":"154855","DOI":"10.1016\/j.cej.2024.154855","volume":"497","author":"Yang","year":"2024","journal-title":"Chem. Eng. J."},{"key":"D6TB00953K\/cit43\/1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S1389-0344(02)00015-1","volume":"19","author":"Seyfert","year":"2002","journal-title":"Biomol. Eng."},{"key":"D6TB00953K\/cit44\/1","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1007\/s00403-025-04424-3","volume":"317","author":"Mao","year":"2025","journal-title":"Arch. Dermatol. Res."},{"key":"D6TB00953K\/cit45\/1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.addr.2018.09.010","volume":"146","author":"Veith","year":"2019","journal-title":"Adv. Drug Delivery Rev."}],"container-title":["Journal of Materials Chemistry B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/TB\/article-pdf\/doi\/10.1039\/D6TB00953K\/0\/D6TB00953K.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T16:49:13Z","timestamp":1784134153000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/TB\/article-lookup\/doi\/10.1039\/D6TB00953K"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":45,"journal-issue":{"issue":"27","published-print":{"date-parts":[[2026,7,15]]}},"URL":"https:\/\/doi.org\/10.1039\/d6tb00953k","relation":{},"ISSN":["2050-750X","2050-7518"],"issn-type":[{"value":"2050-750X","type":"print"},{"value":"2050-7518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}