{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T15:30:32Z","timestamp":1793374232216,"version":"4.5.0"},"reference-count":57,"publisher":"Royal Society of Chemistry (RSC)","issue":"38","license":[{"start":{"date-parts":[[2027,9,9]],"date-time":"2027-09-09T00:00:00Z","timestamp":1820448000000},"content-version":"am","delay-in-days":616,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82560842"],"award-info":[{"award-number":["82560842"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515012294"],"award-info":[{"award-number":["2024A1515012294"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007471","name":"Applied Basic Research Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["202501AZ070001-024"],"award-info":[{"award-number":["202501AZ070001-024"]}],"id":[{"id":"10.13039\/100007471","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007471","name":"Applied Basic Research Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["202001AZ070001-008"],"award-info":[{"award-number":["202001AZ070001-008"]}],"id":[{"id":"10.13039\/100007471","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008871","name":"Yunnan Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["202303AC100025"],"award-info":[{"award-number":["202303AC100025"]}],"id":[{"id":"10.13039\/501100008871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["J. Mater. Chem. B"],"abstract":"<jats:p>KGNVs alleviate LPS-induced acute inflammatory injury in RAW264.7 macrophages and zebrafish by suppressing NF-\u03baB\/p65-associated inflammatory activation, oxidative stress, mitochondrial dysfunction, and caspase-3-dependent apoptosis.<\/jats:p>","DOI":"10.1039\/d6tb01326k","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:43:36Z","timestamp":1788968616000},"page":"11825-11840","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>Kaempferia galanga<\/i>\n                    L.-derived nanovesicles for protection against acute inflammation\n                    <i>via<\/i>\n                    the NF-\u03baB signaling pathway"],"prefix":"10.1039","volume":"14","author":[{"given":"Ziyue","family":"Li","sequence":"first","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"},{"name":"College of Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"},{"name":"College of Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqiao","family":"Li","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meijing","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haihong","family":"Li","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penghong","family":"Fu","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong'e","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"},{"name":"College of Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yikun","family":"Shang","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"},{"name":"College of Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qitong","family":"Qin","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Su","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8713-4287","authenticated-orcid":false,"given":"Xujie","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3794-8519","authenticated-orcid":false,"given":"Xin","family":"Cheng","sequence":"additional","affiliation":[{"name":"College of Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"He","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6TB01326K\/cit1\/1","doi-asserted-by":"crossref","first-page":"124960","DOI":"10.1016\/j.ijpharm.2024.124960","volume":"668","author":"Cao","year":"2025","journal-title":"Int. J. Pharm."},{"key":"D6TB01326K\/cit2\/1","doi-asserted-by":"crossref","first-page":"e20240066","DOI":"10.1002\/INMD.20240066","volume":"3","author":"Lei","year":"2025","journal-title":"Interdiscip. Med."},{"key":"D6TB01326K\/cit3\/1","doi-asserted-by":"crossref","first-page":"5891","DOI":"10.1016\/j.apsb.2025.08.012","volume":"15","author":"Guan","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"key":"D6TB01326K\/cit4\/1","doi-asserted-by":"crossref","first-page":"5664","DOI":"10.1039\/D6TB00226A","volume":"14","author":"Luo","year":"2026","journal-title":"J. Mater. Chem. B"},{"key":"D6TB01326K\/cit5\/1","doi-asserted-by":"crossref","first-page":"123812","DOI":"10.1016\/j.ijpharm.2024.123812","volume":"652","author":"Zhao","year":"2024","journal-title":"Int. J. Pharm."},{"key":"D6TB01326K\/cit6\/1","doi-asserted-by":"crossref","first-page":"5722","DOI":"10.1039\/D4TB00423J","volume":"12","author":"Mo","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"D6TB01326K\/cit7\/1","doi-asserted-by":"crossref","first-page":"125359","DOI":"10.1016\/j.ijpharm.2025.125359","volume":"673","author":"Ma","year":"2025","journal-title":"Int. J. Pharm."},{"key":"D6TB01326K\/cit8\/1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s13105-021-00844-7","volume":"78","author":"Zhou","year":"2022","journal-title":"J. Physiol. Biochem."},{"key":"D6TB01326K\/cit9\/1","doi-asserted-by":"crossref","first-page":"12833","DOI":"10.1021\/acsnano.5c19988","volume":"20","author":"Li","year":"2026","journal-title":"ACS Nano"},{"key":"D6TB01326K\/cit10\/1","doi-asserted-by":"crossref","first-page":"8971","DOI":"10.1039\/D1TB01681D","volume":"9","author":"Gao","year":"2021","journal-title":"J. Mater. Chem. B"},{"key":"D6TB01326K\/cit11\/1","doi-asserted-by":"crossref","first-page":"11767","DOI":"10.1039\/D5TB00886G","volume":"13","author":"Pareek","year":"2025","journal-title":"J. Mater. Chem. B"},{"key":"D6TB01326K\/cit12\/1","doi-asserted-by":"crossref","first-page":"e20240117","DOI":"10.1002\/INMD.20240117","volume":"3","author":"Yang","year":"2025","journal-title":"Interdiscip. Med."},{"key":"D6TB01326K\/cit13\/1","doi-asserted-by":"crossref","first-page":"109942","DOI":"10.1016\/j.cclet.2024.109942","volume":"36","author":"Li","year":"2025","journal-title":"Chin. Chem. Lett."},{"key":"D6TB01326K\/cit14\/1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0140-6736(24)02263-3","volume":"405","author":"Navarro-Compan","year":"2025","journal-title":"Lancet"},{"key":"D6TB01326K\/cit15\/1","doi-asserted-by":"crossref","first-page":"e20230055","DOI":"10.1002\/INMD.20230055","volume":"2","author":"Li","year":"2024","journal-title":"Interdiscip. Med."},{"key":"D6TB01326K\/cit16\/1","doi-asserted-by":"crossref","first-page":"e20240011","DOI":"10.1002\/INMD.20240011","volume":"2","author":"Wang","year":"2024","journal-title":"Interdiscip. Med."},{"key":"D6TB01326K\/cit17\/1","doi-asserted-by":"crossref","first-page":"e20240101","DOI":"10.1002\/INMD.20240101","volume":"3","author":"Yang","year":"2025","journal-title":"Interdiscip. Med."},{"key":"D6TB01326K\/cit18\/1","doi-asserted-by":"crossref","first-page":"106733","DOI":"10.1016\/j.phrs.2023.106733","volume":"190","author":"Yi","year":"2023","journal-title":"Pharmacol. Res."},{"key":"D6TB01326K\/cit19\/1","doi-asserted-by":"crossref","first-page":"10609","DOI":"10.1039\/D5TB00861A","volume":"13","author":"Sun","year":"2025","journal-title":"J. Mater. Chem. B"},{"key":"D6TB01326K\/cit20\/1","doi-asserted-by":"crossref","first-page":"5853","DOI":"10.1039\/D2TB01190E","volume":"10","author":"Li","year":"2022","journal-title":"J. Mater. Chem. B"},{"key":"D6TB01326K\/cit21\/1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1186\/s12951-025-03366-2","volume":"23","author":"Wei","year":"2025","journal-title":"J. Nanobiotechnol."},{"key":"D6TB01326K\/cit22\/1","doi-asserted-by":"crossref","first-page":"0469","DOI":"10.34133\/research.0469","volume":"7","author":"Li","year":"2024","journal-title":"Research"},{"key":"D6TB01326K\/cit23\/1","first-page":"96","volume":"59","author":"Xu","year":"2026","journal-title":"Bioact. Mater."},{"key":"D6TB01326K\/cit24\/1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1186\/s12951-023-02065-0","volume":"21","author":"Zhu","year":"2023","journal-title":"J. Nanobiotechnol."},{"key":"D6TB01326K\/cit25\/1","doi-asserted-by":"crossref","first-page":"4725","DOI":"10.1021\/acs.jafc.1c07306","volume":"70","author":"Yin","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"D6TB01326K\/cit26\/1","doi-asserted-by":"crossref","first-page":"12975","DOI":"10.2147\/IJN.S526819","volume":"20","author":"Li","year":"2025","journal-title":"Int. J. Nanomedicine"},{"key":"D6TB01326K\/cit27\/1","doi-asserted-by":"crossref","first-page":"34785","DOI":"10.1021\/acsnano.5c10112","volume":"19","author":"Liu","year":"2025","journal-title":"ACS Nano"},{"key":"D6TB01326K\/cit28\/1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s12951-025-03897-8","volume":"24","author":"Lin","year":"2026","journal-title":"J. Nanobiotechnol."},{"key":"D6TB01326K\/cit29\/1","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.2147\/IJN.S444686","volume":"19","author":"Nemidkanam","year":"2024","journal-title":"Int. J. Nanomed."},{"key":"D6TB01326K\/cit30\/1","doi-asserted-by":"crossref","first-page":"11319","DOI":"10.1039\/D4FO04321A","volume":"15","author":"Zeng","year":"2024","journal-title":"Food Funct."},{"key":"D6TB01326K\/cit31\/1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1186\/s12951-023-01919-x","volume":"21","author":"Ou","year":"2023","journal-title":"J. Nanobiotechnol."},{"key":"D6TB01326K\/cit32\/1","doi-asserted-by":"crossref","first-page":"13931","DOI":"10.1038\/s41598-023-41224-z","volume":"13","author":"Zhao","year":"2023","journal-title":"Sci. Rep."},{"key":"D6TB01326K\/cit33\/1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s13020-025-01203-0","volume":"21","author":"Huang","year":"2026","journal-title":"Chin. Med."},{"key":"D6TB01326K\/cit34\/1","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1016\/j.immuni.2023.10.004","volume":"56","author":"Miao","year":"2023","journal-title":"Immunity"},{"key":"D6TB01326K\/cit35\/1","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/s41419-025-08291-8","volume":"17","author":"Lozano-Gil","year":"2026","journal-title":"Cell Death Dis."},{"key":"D6TB01326K\/cit36\/1","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1080\/15548627.2025.2487037","volume":"21","author":"Zhu","year":"2025","journal-title":"Autophagy"},{"key":"D6TB01326K\/cit37\/1","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1186\/s40425-019-0817-4","volume":"7","author":"Cao","year":"2019","journal-title":"J. Immunother. Cancer"},{"key":"D6TB01326K\/cit38\/1","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1038\/s41556-025-01790-y","volume":"27","author":"Lange","year":"2025","journal-title":"Nat. Cell Biol."},{"key":"D6TB01326K\/cit39\/1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1186\/s12944-025-02642-2","volume":"24","author":"Thakkar","year":"2025","journal-title":"Lipids Health Dis."},{"key":"D6TB01326K\/cit40\/1","doi-asserted-by":"crossref","first-page":"121178","DOI":"10.1016\/j.biomaterials.2021.121178","volume":"279","author":"Zu","year":"2021","journal-title":"Biomaterials"},{"key":"D6TB01326K\/cit41\/1","doi-asserted-by":"crossref","first-page":"156806","DOI":"10.1016\/j.phymed.2025.156806","volume":"143","author":"Gu","year":"2025","journal-title":"Phytomedicine"},{"key":"D6TB01326K\/cit42\/1","doi-asserted-by":"crossref","first-page":"156677","DOI":"10.1016\/j.phymed.2025.156677","volume":"141","author":"Ni","year":"2025","journal-title":"Phytomedicine"},{"key":"D6TB01326K\/cit43\/1","doi-asserted-by":"crossref","first-page":"116969","DOI":"10.1016\/j.jep.2023.116969","volume":"318","author":"Chi","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"D6TB01326K\/cit44\/1","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1186\/s12951-024-02500-w","volume":"22","author":"Chen","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"D6TB01326K\/cit45\/1","doi-asserted-by":"crossref","first-page":"108092","DOI":"10.1016\/j.biotechadv.2022.108092","volume":"63","author":"Giancaterino","year":"2023","journal-title":"Biotechnol. Adv."},{"key":"D6TB01326K\/cit46\/1","doi-asserted-by":"crossref","first-page":"217772","DOI":"10.1016\/j.canlet.2025.217772","volume":"625","author":"Bai","year":"2025","journal-title":"Cancer Lett."},{"key":"D6TB01326K\/cit47\/1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12951-025-03096-5","volume":"23","author":"Han","year":"2025","journal-title":"J. Nanobiotechnol."},{"key":"D6TB01326K\/cit48\/1","doi-asserted-by":"crossref","first-page":"126717","DOI":"10.1016\/j.ijpharm.2026.126717","volume":"693","author":"Chen","year":"2026","journal-title":"Int. J. Pharm."},{"key":"D6TB01326K\/cit49\/1","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1186\/s12967-023-04763-7","volume":"21","author":"Yuan","year":"2023","journal-title":"J. Transl. Med."},{"key":"D6TB01326K\/cit50\/1","doi-asserted-by":"crossref","first-page":"6978936","DOI":"10.1155\/2016\/6978936","volume":"2016","author":"Molteni","year":"2016","journal-title":"Mediators Inflamm."},{"key":"D6TB01326K\/cit51\/1","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.tcb.2020.09.004","volume":"30","author":"Pizzuto","year":"2020","journal-title":"Trends Cell Biol."},{"key":"D6TB01326K\/cit52\/1","doi-asserted-by":"crossref","first-page":"3667","DOI":"10.1007\/s00018-019-03113-5","volume":"76","author":"Pizzuto","year":"2019","journal-title":"Cell. Mol. Life Sci."},{"key":"D6TB01326K\/cit53\/1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1042\/CS20243515","volume":"139","author":"Schroeder","year":"2025","journal-title":"Clin. Sci."},{"key":"D6TB01326K\/cit54\/1","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1111\/bph.13762","volume":"174","author":"Zou","year":"2017","journal-title":"Br. J. Pharmacol."},{"key":"D6TB01326K\/cit55\/1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.ccell.2024.12.001","volume":"43","author":"Ma","year":"2025","journal-title":"Cancer Cell"},{"key":"D6TB01326K\/cit56\/1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/s41419-023-05716-0","volume":"14","author":"Chen","year":"2023","journal-title":"Cell Death Dis."},{"key":"D6TB01326K\/cit57\/1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1186\/s13098-024-01557-9","volume":"16","author":"Sun","year":"2024","journal-title":"Diabetol. Metab. Syndr."}],"updated-by":[{"DOI":"10.1039\/d6tb90157c","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:00:00Z","timestamp":1793318400000}}],"container-title":["Journal of Materials Chemistry B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/TB\/article-pdf\/doi\/10.1039\/D6TB01326K\/0\/D6TB01326K.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T14:31:06Z","timestamp":1793370666000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/TB\/article-lookup\/doi\/10.1039\/D6TB01326K"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":57,"journal-issue":{"issue":"38","published-print":{"date-parts":[[2026,10,7]]}},"URL":"https:\/\/doi.org\/10.1039\/d6tb01326k","relation":{},"ISSN":["2050-750X","2050-7518"],"issn-type":[{"value":"2050-750X","type":"print"},{"value":"2050-7518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}