{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:26:23Z","timestamp":1756995983747},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"1","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1969,1,1]]},"abstract":"<jats:p>1. 5,6-Monoepoxy-3-dehydroretinal was synthesized from 3-dehydroretinyl acetate and characterized. 2. When fed to vitamin A-deficient rats, 5,6-monoepoxy-3-dehydroretinal was converted into 5,6-monoepoxy-3-dehydrovitamin A and stored in the liver. 3. It was demonstrated that the rat possesses the necessary enzymes for the reduction and oxidation of 5,6-monoepoxy-3-dehydroretinal to the corresponding alcohol and acid respectively. 4. The biological potency of the epoxy-3-dehydroretinal by the rat-growth assay (determined by USP XIV procedure) was 1\u00b707% of that of vitamin A.<\/jats:p>","DOI":"10.1042\/bj1110023","type":"journal-article","created":{"date-parts":[[2015,8,10]],"date-time":"2015-08-10T19:18:21Z","timestamp":1439234301000},"page":"23-26","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Preparation, properties and metabolism of 5,6-monoepoxy-3-dehydroetinal"],"prefix":"10.1042","volume":"111","author":[{"given":"A. Krishna","family":"Mallia","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Indian Institute of Science, Bangalore 12, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. R.","family":"Lakshmanan","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Indian Institute of Science, Bangalore 12, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. V.","family":"John","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Indian Institute of Science, Bangalore 12, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. R.","family":"Cama","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Indian Institute of Science, Bangalore 12, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Biochemical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/111\/1\/23\/762319\/bj1110023.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/111\/1\/23\/762319\/bj1110023.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T20:55:37Z","timestamp":1638219337000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/biochemj\/article\/111\/1\/23\/4940\/Preparation-properties-and-metabolism-of-5-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1969,1,1]]}},"URL":"https:\/\/doi.org\/10.1042\/bj1110023","relation":{},"ISSN":["0306-3283"],"issn-type":[{"value":"0306-3283","type":"print"}],"subject":[],"published":{"date-parts":[[1969,1,1]]}}}