{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T15:37:45Z","timestamp":1775230665776,"version":"3.50.1"},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"1","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1970,11,1]]},"abstract":"<jats:p>A protein fraction was isolated from guinea-pig liver that binds triethyltin with an affinity of approx. 2\u00d7106m\u22121 at pH8.0. It was shown that the protein responsible for binding 70% of the triethyltin found in guinea-pig liver after injection of radioactively labelled triethyltin is at most a few per cent of the total liver protein. Evidence is presented from the kinetics of loss of binding and loss of certain amino acids on photo-oxidation with either Methylene Blue or Rose Bengal that each binding site consists of two histidine residues.<\/jats:p>","DOI":"10.1042\/bj1200151","type":"journal-article","created":{"date-parts":[[2015,8,10]],"date-time":"2015-08-10T19:30:48Z","timestamp":1439235048000},"page":"151-157","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["The interaction of triethyltin with a component of guinea-pig liver supernatant. Evidence for histidine in the binding sites"],"prefix":"10.1042","volume":"120","author":[{"given":"M. S.","family":"Rose","sequence":"first","affiliation":[{"name":"Biochemical Mechanisms Section, Medical Research Council Toxicology Unit, Woodmansterne Road, Carshalton, Surrey, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. A.","family":"Lock","sequence":"additional","affiliation":[{"name":"Biochemical Mechanisms Section, Medical Research Council Toxicology Unit, Woodmansterne Road, Carshalton, Surrey, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Biochemical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/120\/1\/151\/768823\/bj1200151.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/120\/1\/151\/768823\/bj1200151.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T13:19:14Z","timestamp":1637932754000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/biochemj\/article\/120\/1\/151\/4592\/The-interaction-of-triethyltin-with-a-component-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,11,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1970,11,1]]}},"URL":"https:\/\/doi.org\/10.1042\/bj1200151","relation":{},"ISSN":["0306-3283"],"issn-type":[{"value":"0306-3283","type":"print"}],"subject":[],"published":{"date-parts":[[1970,11,1]]}}}