{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T12:42:54Z","timestamp":1700743374832},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"4","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1973,12,1]]},"abstract":"<jats:p>A specimen of intestinal glycoprotein isolated from the pig and two samples of dextran, all of which are polydisperse (that is, the preparations may be regarded as consisting of a continuous distribution of molecular weights), have been examined in the ultracentrifuge under meniscus-depletion conditions at equilibrium. They are compared with each other and with a glycoprotein from Cysticercus tenuicollis cyst fluid which is almost monodisperse. The quantity c\u2212\u2153(c=concentration) is plotted against \u03be (the reduced radius); this plot is linear when the molecular-weight distribution approximates to the \u2018most probable\u2019, i.e. when Mn:Mw:Mz: M(z+1)....... is as 1:2:3:4: etc. The use of this plot, and related procedures, to evaluate qualitatively and semi-quantitatively molecular-weight distribution functions where they can be realistically approximated to Schulz distributions is discussed. The theoretical basis is given in an Appendix.<\/jats:p>","DOI":"10.1042\/bj1350649","type":"journal-article","created":{"date-parts":[[2015,8,10]],"date-time":"2015-08-10T19:50:41Z","timestamp":1439236241000},"page":"649-653","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["A new general method for the assessment of the molecular-weight distribution of polydisperse preparations. Its application to an intestinal epithelial glycoprotein and two dextran samples, and comparison with a monodisperse glycoprotein"],"prefix":"10.1042","volume":"135","author":[{"given":"Richard A.","family":"Gibbons","sequence":"first","affiliation":[{"name":"Agricultural Research Council Institute for Research on Animal Diseases, Compton, Newbury, Berks., U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen N.","family":"Dixon","sequence":"additional","affiliation":[{"name":"Agricultural Research Council Institute for Research on Animal Diseases, Compton, Newbury, Berks., U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David H.","family":"Pocock","sequence":"additional","affiliation":[{"name":"Agricultural Research Council Institute for Research on Animal Diseases, Compton, Newbury, Berks., U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Biochemical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/135\/4\/649\/561832\/bj1350649.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/135\/4\/649\/561832\/bj1350649.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T16:06:52Z","timestamp":1637942812000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/biochemj\/article\/135\/4\/649\/9182\/A-new-general-method-for-the-assessment-of-the"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,12,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1973,12,1]]}},"URL":"https:\/\/doi.org\/10.1042\/bj1350649","relation":{},"ISSN":["0264-6021"],"issn-type":[{"value":"0264-6021","type":"print"}],"subject":[],"published":{"date-parts":[[1973,12,1]]}}}