{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:07:47Z","timestamp":1787004467881,"version":"build-2736575974"},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"2","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1974,5,15]]},"abstract":"<jats:p>1. An organism isolated from sewage and identified as an Alcaligenes sp. utilized benzenesulphonate, toluene-p-sulphonate or phenylethane-p-sulphonate as sole source of carbon and energy for growth. Higher alkylbenzenesulphonate homologues and the hydrocarbons, benzene, toluene, phenylethane and 1-phenyldodecane were not utilized. 2. 2-Phenylpropanesulphonate was metabolized to 4-isopropylcatechol. 3. 1-Phenylpropanesulphonate was metabolized to an ortho-diol, which was tentatively identified, in the absence of an authentic specimen, as 4-n-propylcatechol. 4. In the presence of 4-isopropylcatechol, which inhibited catechol 2,3-dioxygenase, 4-ethylcatechol accumulated in cultures growing on phenylethane-p-sulphonate. 5. Authentic samples of catechol, 3-methylcatechol, 4-methylcatechol, 4-ethylcatechol and 3-isopropylcatechol were oxidized by heat-treated extracts to the corresponding 2-hydroxyalkylmuconic semialdehydes. Ring cleavage occurred between C-2 and C-3. 6. The catechol derived from 1-phenylpropanesulphonate was oxygenated by catechol 2,3-dioxygenase to a compound with all the properties of a 2-hydroxyalkylmuconic semialdehyde, but it was not rigorously identified. 7. The catechol 2,3-dioxygenase induced by growth on benzenesulphonate, toluene-p-sulphonate or phenylethane-p-sulphonate showed a constant ratio of specific activities with catechol, 3-methylcatechol, 4-methylcatechol and 4-ethylcatechol that was independent of the growth substrate. At 60\u00b0C, activity towards these substrates declined at an identical first-order rate. 8. Enzymes of the \u2018ortho\u2019 pathway of catechol metabolism were present in small amounts in cells grown on benzenesulphonate, toluene-p-sulphonate or phenylethane-p-sulphonate. 9. The catechol 1,2-dioxygenase oxidized the alkylcatechols, but the rates and the total extents of oxidation were less than for catechol itself. The oxidation products of these alkylcatechols were not further metabolized.<\/jats:p>","DOI":"10.1042\/bj1400121","type":"journal-article","created":{"date-parts":[[2015,8,10]],"date-time":"2015-08-10T15:53:43Z","timestamp":1439222023000},"page":"121-134","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Microbial degradation of alkylbenzenesulphonates. Metabolism of homologues of short alkyl-chain length by an\n                    <i>Alcaligenes<\/i>\n                    sp"],"prefix":"10.1042","volume":"140","author":[{"given":"J. Anthony","family":"Bird","sequence":"first","affiliation":[{"name":"Microbiology Group, Department of Botany, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald B.","family":"Cain","sequence":"additional","affiliation":[{"name":"Microbiology Group, Department of Botany, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","container-title":["Biochemical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/140\/2\/121\/781097\/bj1400121.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/140\/2\/121\/781097\/bj1400121.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T11:03:00Z","timestamp":1637924580000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/biochemj\/article\/140\/2\/121\/9093\/Microbial-degradation-of-alkylbenzenesulphonates"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,5,15]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1974,5,15]]}},"URL":"https:\/\/doi.org\/10.1042\/bj1400121","relation":{},"ISSN":["0306-3283"],"issn-type":[{"value":"0306-3283","type":"print"}],"subject":[],"published":{"date-parts":[[1974,5,15]]}}}