{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T11:54:22Z","timestamp":1757591662745},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"3","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1982,3,15]]},"abstract":"<jats:p>1. The metabolism of hepatic glycogen, labelled with [6-3H]glucose at day 19.5 of gestation and with 14C from [U-14C]galactose at delivery, was followed for 10 h in food-deprived gsd\/gsd and control (GSD\/GSD) neonatal rats. 2. In the affected pups glycogen was maintained at 12% (w\/w) and there was no loss of incorporated radioactivity. 3. The 3H and 14C in glycogen from the controls were both decreased by 80%, but 14C was removed at 0-5 h and [6-3H]glucose at 5-10 h. 4. Blood glucose concentrations in the unaffected neonatal rats fell from 5.3 mM at 20 min to 1.7 mM after 10 h. In the gsd\/gsd pups blood glucose concentration was decreased from 2 mM at birth to 0.3 mM at 2.5 h: it was maintained at 0.8 mM between 5 and 10 h. 5. In neonatal rats that had been dead for 10 h, hepatic glycogen was decreased by 34% in the controls and by 22% in the gsd\/gsd pups. These results demonstrate that liver from the affected rats contains glycogenolytic activity, but that it is not expressed in living tissue.<\/jats:p>","DOI":"10.1042\/bj2020623","type":"journal-article","created":{"date-parts":[[2015,8,10]],"date-time":"2015-08-10T20:33:10Z","timestamp":1439238790000},"page":"623-629","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Glycogen metabolism in the liver of the neonatal <i>gsd\/gsd<\/i> and control (<i>GSD\/GSD<\/i>) rat"],"prefix":"10.1042","volume":"202","author":[{"given":"D G","family":"Clark","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S D","family":"Neville","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Brinkman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O H","family":"Filsell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Biochemical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/202\/3\/623\/576979\/bj2020623.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/202\/3\/623\/576979\/bj2020623.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T12:26:59Z","timestamp":1637843219000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/biochemj\/article\/202\/3\/623\/13211\/Glycogen-metabolism-in-the-liver-of-the-neonatal"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,3,15]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1982,3,15]]}},"URL":"https:\/\/doi.org\/10.1042\/bj2020623","relation":{},"ISSN":["0264-6021"],"issn-type":[{"value":"0264-6021","type":"print"}],"subject":[],"published":{"date-parts":[[1982,3,15]]}}}