{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:40:29Z","timestamp":1790836829647,"version":"4.1.0"},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"2","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1986,7,15]]},"abstract":"<jats:p>The superoxide radical O2.-, whether produced by the xanthine\/xanthine oxidase reaction or infused as KO2, solubilized by a crown ether in dry dimethyl sulphoxide, initiated a free-radical chain oxidation of anionic 2-nitropropane. Superoxide dismutase, but not catalase, inhibited oxidation of the nitroalkane. Xanthine oxidase suffered a syncatalytic inactivation, during the co-oxidation of 2-nitropropane, which was reversed by dialysis. Cyanide exacerbated this syncatalytic inactivation and rendered it irreversible. The frequently observed oxidations of nitroalkanes by flavoenzymes now need to be re-examined to clarify the extent to which O2.--initiated free-radical chain oxidation contributed to the overall nitroalkane oxidation.<\/jats:p>","DOI":"10.1042\/bj2370505","type":"journal-article","created":{"date-parts":[[2015,8,10]],"date-time":"2015-08-10T20:54:03Z","timestamp":1439240043000},"page":"505-510","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Free-radical chain oxidation of 2-nitropropane initiated and propagated by superoxide"],"prefix":"10.1042","volume":"237","author":[{"given":"C F","family":"Kuo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Fridovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","container-title":["Biochemical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/237\/2\/505\/587481\/bj2370505.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/237\/2\/505\/587481\/bj2370505.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T16:00:18Z","timestamp":1637856018000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/biochemj\/article\/237\/2\/505\/21961\/Free-radical-chain-oxidation-of-2-nitropropane"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,7,15]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1986,7,15]]}},"URL":"https:\/\/doi.org\/10.1042\/bj2370505","relation":{},"ISSN":["0264-6021","1470-8728"],"issn-type":[{"value":"0264-6021","type":"print"},{"value":"1470-8728","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,7,15]]}}}