{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:29:40Z","timestamp":1791325780274,"version":"4.3.1"},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"3","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2001,9,15]]},"abstract":"<jats:p>This paper describes structural characterization by NMR, MS and degradative studies of mucin glycans from normal human descending colon obtained freshly at autopsy. The saccharides were mainly based on core 3 (GlcNAc\u03b21-3GalNAc). Among the terminal saccharide determinants Sda\/Cad-antigen-like structures were prominent, and Lewis x, sialyl Lewis x and sulphated Lewis x were found as minor components, whereas blood group H and A antigenic determinants were absent. The saccharides were markedly different from those of mucins from colon cancers or colon cancer cell lines analysed so far, in which cores 1 and 2 are prominent features, and in which various other terminal determinants have been found, but not Sda\/Cad.<\/jats:p>","DOI":"10.1042\/bj3580657","type":"journal-article","created":{"date-parts":[[2015,8,10]],"date-time":"2015-08-10T22:16:15Z","timestamp":1439244975000},"page":"657-664","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Sda-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon"],"prefix":"10.1042","volume":"358","author":[{"given":"Calliope","family":"CAPON","sequence":"first","affiliation":[{"name":"Laboratoire de Glycobiologie structurale et fonctionnelle, Unit\u00e9 Mixte du Centre National de la Recherche Scientifique 8576, Universit\u00e9 des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"MAES","sequence":"additional","affiliation":[{"name":"Laboratoire de Glycobiologie structurale et fonctionnelle, Unit\u00e9 Mixte du Centre National de la Recherche Scientifique 8576, Universit\u00e9 des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"MICHALSKI","sequence":"additional","affiliation":[{"name":"Laboratoire de Glycobiologie structurale et fonctionnelle, Unit\u00e9 Mixte du Centre National de la Recherche Scientifique 8576, Universit\u00e9 des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hakon","family":"LEFFLER","sequence":"additional","affiliation":[{"name":"Sect MIG (Microbiology, Immunology, Glycobiology), Inst. Laboratory Medicine, Lund University, S\u00f6lvegatan 23, SE 22362 Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young S.","family":"KIM","sequence":"additional","affiliation":[{"name":"Gastrointestinal Research Laboratory (151M2), Veterans Affairs Medical Center, Departments of Medicine and Pathology, University of California, San Francisco, CA 94121, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","published-online":{"date-parts":[[2001,9,10]]},"container-title":["Biochemical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/358\/3\/657\/707852\/bj3580657.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/biochemj\/article-pdf\/358\/3\/657\/707852\/bj3580657.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T11:50:54Z","timestamp":1637581854000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/biochemj\/article\/358\/3\/657\/39647\/Sda-antigen-like-structures-carried-on-core-3-are"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,9,10]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2001,9,15]]}},"URL":"https:\/\/doi.org\/10.1042\/bj3580657","relation":{},"ISSN":["0264-6021","1470-8728"],"issn-type":[{"value":"0264-6021","type":"print"},{"value":"1470-8728","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,9,10]]}}}