{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T17:19:37Z","timestamp":1781630377166,"version":"3.54.5"},"reference-count":35,"publisher":"Portland Press Ltd.","issue":"5","license":[{"start":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T00:00:00Z","timestamp":1568851200000},"content-version":"vor","delay-in-days":141,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We assessed the relationship between the volume of epicardial adipose tissue and long-term outcomes in patients with coronary heart disease (CHD) undergoing percutaneous coronary intervention (PCI). The patients with CHD were followed for at least 2 years after PCI. The epicardial adipose tissue volume (EATV) was measured using multi-slice computed tomography. Cox regression analysis was used to examine the relationship between EATV and clinical outcome. In this study, 500 patients were enrolled and followed up for a median of 25.2 months. The incidence of adverse cardiovascular events was 12.4%. No significant differences were observed in age, sex, proportion of patients with hypertension or diabetes, smoking, drinking, total cholesterol, triglyceride, high-density lipoprotein, or unstable angina pectoris among different EATV quartiles (P&amp;gt;0.05). The EATV was associated with body mass index (P&amp;lt;0.0001), low-density lipoprotein level (P=0.039), high-sensitivity C-reactive protein level (P&amp;lt;0.001), uric acid level (P=0.004), adiponectin level (P&amp;lt;0.001), and left ventricular ejection fraction (P&amp;lt;0.001). Kaplan\u2013Meier analysis indicated a significant difference in survival rate of patients in EATV quartile 1 versus 4 (P=0.019). After adjusting for confounding factors, EATV quartile 4 (&amp;gt;216.15 cm3) was still associated with adverse cardiovascular outcomes (HR = 1.98, 95% CI: 1.15\u20134.47, P=0.023) compared with quartile 1 (&amp;lt;101.58 cm3). Our data suggest that EATV is an independent predictor of long-term major adverse cardiovascular events in CHD patients after PCI. Therefore, assessment of EATV using multi-slice computed tomography may contribute to risk stratification in these patients.<\/jats:p>","DOI":"10.1042\/bsr20182278","type":"journal-article","created":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T18:19:09Z","timestamp":1555093149000},"update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Association between epicardial adipose tissue and adverse outcomes in coronary heart disease patients with percutaneous coronary intervention"],"prefix":"10.1042","volume":"39","author":[{"given":"Changqing","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Emergency, The Second Affiliated Hospital of Henan University of Chinese Medicine (Henan Province Hospital of Traditional Chinese Medicine), Zhengzhou, Henan Province 450002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helei","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Emergency, The Second Affiliated Hospital of Henan University of Chinese Medicine (Henan Province Hospital of Traditional Chinese Medicine), Zhengzhou, Henan Province 450002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4439-4470","authenticated-orcid":false,"given":"Zhentao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular, Henan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan Province 450002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","published-online":{"date-parts":[[2019,5,7]]},"reference":[{"key":"2021111619353716000_B1","doi-asserted-by":"publisher","first-page":"697240","DOI":"10.1155\/2012\/697240","article-title":"Diabetes and coronary heart disease: a risk factor for the global epidemic","volume":"2012","author":"Chiha","year":"2012","journal-title":"Int. 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