{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T01:07:49Z","timestamp":1782349669814,"version":"3.54.5"},"reference-count":30,"publisher":"Portland Press Ltd.","issue":"4","license":[{"start":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T00:00:00Z","timestamp":1567987200000},"content-version":"vor","delay-in-days":161,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,4,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Background: The present study aimed to evaluate serum 25-hydroxy vitamin D (25(OH) D) levels in Chinese patients with idiopathic benign paroxysmal positional vertigo (BPPV) and to investigate the possible relationship between the occurrence and recurrence of idiopathic BPPV and low 25(OH) D levels. Methods: Between 1 January 2017 and 31 May, 2018, consecutively older patients (age, older than 50 years) with idiopathic BPPV were recruited in the present study. For each patient, 2:1 sex and age matched healthy people were assigned as the control group. The influence of 25(OH) D levels on BPPV and recurrent BPPV were performed by binary logistic regression analysis. Results: In the present study, 174 patients with BPPV and 348 controls were included. The serum levels of 25(OH) D in those patients were lower than in those controls (P&amp;lt;0.001). One hundred eight patients were found to have vitamin D deficiency; thus, the prevalence was 62.1%, which was higher than that in the controls (42.8%). The data showed that patients with recurrent BPPV (N = 31) had lower serum levels of 25(OH) D compared with those who were not (11.2 ng\/ml [interquartile range, 7.2\u201320.8 ng\/ml] vs 18.7 ng\/ml [14.2\u201324.8 ng\/ml]). The regression analyses demonstrated that vitamin D deficiency was associated with BPPV and recurrent BPPV with an odds ratio of 2.15 (95% confidence interval [CI], 1.30\u20134.32; P=0.006) and 5.16 (95% CI, 1.00\u201334.12; P=0.05). Conclusion: Decreased serum levels of 25(OH)D were associated with the occurrence and recurrence of BPPV in a Chinese population, independent of other baseline markers.<\/jats:p>","DOI":"10.1042\/bsr20190142","type":"journal-article","created":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T16:17:06Z","timestamp":1554740226000},"update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Serum levels of 25-hydroxy vitamin D correlate with idiopathic benign paroxysmal positional vertigo"],"prefix":"10.1042","volume":"39","author":[{"given":"Jing","family":"Ding","sequence":"first","affiliation":[{"name":"Department of Neurology, Hanting District People\u2019s Hospital, Weifang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pain, Qian Foshan Attached Hospital of Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Kuan","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Pain, Liaocheng Second People\u2019s Hospital, Liaocheng, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Bing","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Zhangqiu City Hospital of Traditional Chinese Medicine, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1773-9165","authenticated-orcid":false,"given":"Xudong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pain, Qilu Hospital of Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","published-online":{"date-parts":[[2019,4,30]]},"reference":[{"key":"2021111619280160200_B1","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/1471-2377-14-110","article-title":"Association between osteoporosis and benign paroxysmal positional vertigo: a systematic review","volume":"14","author":"Yu","year":"2014","journal-title":"BMC Neurol."},{"key":"2021111619280160200_B2","doi-asserted-by":"publisher","first-page":"1590","DOI":"10.1056\/NEJM199911183412107","article-title":"Benign paroxysmal positional vertigo","volume":"341","author":"Furman","year":"1999","journal-title":"N. 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