{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:26:19Z","timestamp":1791390379389,"version":"4.3.3"},"reference-count":14,"publisher":"Portland Press Ltd.","issue":"5","license":[{"start":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T00:00:00Z","timestamp":1589846400000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,5,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Laryngeal papillomatosis is a benign disease in the larynx but with the potential to develop into significant complications as a result of its high recurrence rate. CO2 laser and radiofrequency controlled ablation (coblation) have been used to treat recurrent respiratory papillomatosis, but detailed comparisons of their respective treatment outcomes are not fully investigated. This retrospective study examines the procedure time, time interval between interventions, blood loss during operation, post-operative complications and pain scores among patients who received either CO2 laser or radiofrequency coblation interventions for laryngotracheal recurrent respiratory papillomatosis. Compared with CO2 laser intervention, radiofrequency coblation significantly reduced operation time, time interval between interventions, blood loss during operation and number of times bipolar electrocoagulation needed in each procedure. Post-operatively, pain scores after radiofrequency coblation were significantly lower than those after CO2 laser intervention. Incidence rates of post-operative complications, in terms of palate pharyngeal mucosa damage, bleeding and subcutaneous emphysema, were also significantly reduced after radiofrequency coblation. Low-temperature radiofrequency coblation is a superior intervention compared with CO2 laser against laryngotracheal recurrent respiratory papillomatosis.<\/jats:p>","DOI":"10.1042\/bsr20192005","type":"journal-article","created":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T11:23:08Z","timestamp":1589887388000},"update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Low-temperature radiofrequency coblation reduces treatment interval and post-operative pain of laryngotracheal recurrent respiratory papillomatosis"],"prefix":"10.1042","volume":"40","author":[{"given":"Fang","family":"Hao","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, The Second Affiliated Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyan","family":"Yue","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Second Affiliated Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Second Affiliated Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Second Affiliated Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2755-6995","authenticated-orcid":false,"given":"Chunguang","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Second Affiliated Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","published-online":{"date-parts":[[2020,5,26]]},"reference":[{"key":"2021111620125984200_B1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/000348940611500101","article-title":"Recurrent respiratory papillomatosis","volume":"115","author":"Derkay","year":"2006","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"2021111620125984200_B2","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1001\/archotol.126.8.935","article-title":"The cost of juvenile-onset recurrent respiratory papillomatosis","volume":"126","author":"Bishai","year":"2000","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"2021111620125984200_B3","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1001\/archotol.130.9.1039","article-title":"American Society of Pediatric Otolaryngology members\u2019 experience with recurrent respiratory papillomatosis and the use of adjuvant therapy","volume":"130","author":"Schraff","year":"2004","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"2021111620125984200_B4","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1097\/00006534-200102000-00053","article-title":"Coblation: an emerging technology and new technique for soft-tissue surgery","volume":"107","author":"Bortnick","year":"2001","journal-title":"Plast. Reconstr. Surg."},{"key":"2021111620125984200_B5","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1111\/j.1365-2273.2005.00970.x","article-title":"Double-blind randomized controlled study of coblation tonsillotomy versus coblation tonsillectomy on postoperative pain in children","volume":"30","author":"Arya","year":"2005","journal-title":"Clin. Otolaryngol."},{"key":"2021111620125984200_B6","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1177\/194589240602000105","article-title":"Bipolar radiofrequency volumetric tissue reduction of inferior turbinate: does the number of treatment sessions influence the final outcome?","volume":"20","author":"Atef","year":"2006","journal-title":"Am. J. Rhinol."},{"key":"2021111620125984200_B7","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1017\/S0022215109992398","article-title":"Radiofrequency coblation for treatment of advanced laryngotracheal recurrent respiratory papillomatosis","volume":"124","author":"Carney","year":"2010","journal-title":"J. Laryngol. Otol."},{"key":"2021111620125984200_B8","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/0002-9610(51)90269-3","article-title":"Measurement of blood loss during surgical operations","volume":"81","author":"Bonica","year":"1951","journal-title":"Am. J. Surg."},{"key":"2021111620125984200_B9","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1177\/019459989110400206","article-title":"Polymerase chain reaction identification of human papillomavirus DNA in CO2 laser plume from recurrent respiratory papillomatosis","volume":"104","author":"Kashima","year":"1991","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"2021111620125984200_B10","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1001\/archotol.128.4.425","article-title":"Powered instrumentation in the treatment of recurrent respiratory papillomatosis: an alternative to the carbon dioxide laser","volume":"128","author":"El-Bitar","year":"2002","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"2021111620125984200_B11","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1046\/j.1365-2273.2000.00389.x","article-title":"Powered laryngeal shavers and laryngeal papillomatosis: a preliminary report","volume":"25","author":"Patel","year":"2000","journal-title":"Clin Otolaryngol Allied Sci."},{"key":"2021111620125984200_B12","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1097\/00005537-200301000-00026","article-title":"Microdebrider versus CO2 laser removal of recurrent respiratory papillomas: a prospective analysis","volume":"113","author":"Pasquale","year":"2003","journal-title":"Laryngoscope"},{"key":"2021111620125984200_B13","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1017\/S0022215106003069","article-title":"Radiofrequency ablation (coblation): a promising new technique for laryngeal papillomata","volume":"121","author":"Timms","year":"2007","journal-title":"J. Laryngol. Otol."},{"key":"2021111620125984200_B14","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1017\/S0022215111001253","article-title":"Coblation resection of paediatric laryngeal papilloma","volume":"125","author":"Rachmanidou","year":"2011","journal-title":"J. Laryngol. 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