{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T12:13:37Z","timestamp":1788264817793,"version":"build-2803163510"},"reference-count":30,"publisher":"Portland Press Ltd.","issue":"7","license":[{"start":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T00:00:00Z","timestamp":1593043200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,7,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The present study aimed to investigate the relationship between an increase in the pre- and post-operative neutrophil\u2013lymphocyte ratio (NLR) and superficial femoral artery in-stent restenosis (ISR) rate. We recruited 199 patients that underwent superficial femoral artery stenting for lower extremity arteriosclerosis obliterans at our hospital from March 2015 to July 2018. Patients were divided into two groups according to the occurrence of ISR within 1 year (group 1, ISR and group 2, Non-ISR). The after NLR (NLRafter) and NLR change ratio (NLRratio) (P&amp;lt;0.001) were significantly higher in group 1. A NLRafter &amp;gt; 4.3 was associated with an odds ratio of 1.946 (95% CI [1.51\u20132.50]; P&amp;lt;0.001) for the presence of ISR. A NLRratio &amp;gt; 37.5% was associated with an odds ratio of 3.6 (95% CI [2.03\u20136.36]; P&amp;lt;0.001) for occurrence of ISR. A NLRafter level &amp;gt; 4.3 had 75% sensitivity and 76% specificity for the prediction of ISR, as identified by the ROC curve. A NLRratio level &amp;gt; 37.5% predicted ISR with 77% sensitivity and 60% specificity. Multivariate logistic regression analysis demonstrated that NLRratio was the strongest independent predictor of ISR (P&amp;lt;0.001). In conclusions, NLRratio could be used as a prognostic marker in superficial femoral artery stents.<\/jats:p>","DOI":"10.1042\/bsr20193448","type":"journal-article","created":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T10:49:28Z","timestamp":1593082168000},"update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The relationship between neutrophil\u2013lymphocyte ratio and in-stent restenosis in superficial femoral artery"],"prefix":"10.1042","volume":"40","author":[{"given":"Yaobo","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Intervention,The fourth affiliated Hospital of China Medical University, Shenyang, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangfang","family":"Ge","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Intervention,The fourth affiliated Hospital of China Medical University, Shenyang, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbo","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Intervention,The fourth affiliated Hospital of China Medical University, Shenyang, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiapei","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Intervention,The fourth affiliated Hospital of China Medical University, Shenyang, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangshuai","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Intervention,The fourth affiliated Hospital of China Medical University, Shenyang, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinzu","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Intervention,The fourth affiliated Hospital of China Medical University, Shenyang, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaocheng","family":"Kuang","sequence":"additional","affiliation":[{"name":"Department of Intervention,The fourth affiliated Hospital of China Medical University, Shenyang, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Intervention,The fourth affiliated Hospital of China Medical University, Shenyang, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yejun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Intervention,The fourth affiliated Hospital of China Medical University, Shenyang, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenghai","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Computer Tomography Diagnosis, Yan\u2019an People\u2019s Hospital,Yan\u2019an, Shaanxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7500-2551","authenticated-orcid":false,"given":"Liang","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Intervention,The fourth affiliated Hospital of China Medical University, Shenyang, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","published-online":{"date-parts":[[2020,7,2]]},"reference":[{"key":"2021111620190028300_B1","doi-asserted-by":"publisher","first-page":"S5","DOI":"10.1016\/j.jvs.2006.12.037","article-title":"Inter-society consensus for the management of peripheral arterial disease (TASC II)","volume":"45","author":"Norgren","year":"2007","journal-title":"J. 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