{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:38:08Z","timestamp":1753871888647,"version":"3.41.2"},"reference-count":280,"publisher":"Portland Press Ltd.","issue":"7","license":[{"start":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T00:00:00Z","timestamp":1684713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The present severe acute respiratory syndrome-2 (SARS-CoV-2) mediated Coronavirus pandemic (COVID-19) and post-COVID-19 complications affect human life drastically. Patients who have been cured of COVID-19 infection are now experiencing post-COVID-19 associated comorbidities, which have increased mortality rates. The SARS-CoV-2 infection distresses the lungs, kidneys, gastrointestinal tract, and various endocrine glands, including the thyroid. The emergence of variants which includes Omicron (B.1.1.529) and its lineages threaten the world severely. Among different therapeutic approaches, phytochemical-based therapeutics are not only cost-effective but also have lesser side effects. Recently a plethora of studies have shown the therapeutic efficacy of various phytochemicals for the treatment of COVID-19. Besides this, various phytochemicals have been found efficacious in treating several inflammatory diseases, including thyroid-related anomalies. The method of the phytochemical formulation is quick and facile and the raw materials for such herbal preparations are approved worldwide for human use against certain disease conditions. Owing to the advantages of phytochemicals, this review primarily discusses the COVID-19-related thyroid dysfunction and the role of key phytochemicals to deal with thyroid anomaly and post-COVID-19 complications. Further, this review shed light on the mechanism via which COVID-19 and its related complication affect organ function of the body, along with the mechanistic insight into the way by which phytochemicals could help to cure post-COVID-19 complications in thyroid patients. Considering the advantages offered by phytochemicals as a safer and cost-effective medication they can be potentially used to combat COVID-19-associated comorbidities.<\/jats:p>","DOI":"10.1042\/bsr20230293","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T08:39:41Z","timestamp":1684744781000},"update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["COVID-19 associated thyroid dysfunction and other comorbidities and its management using phytochemical-based therapeutics: a natural way"],"prefix":"10.1042","volume":"43","author":[{"given":"Arpana","family":"Parihar","sequence":"first","affiliation":[{"name":"1Industrial Waste Utilization, Nano and Biomaterials, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal 462026, MP, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivani","family":"Malviya","sequence":"additional","affiliation":[{"name":"2Department of Biochemistry and Genetics, Barkatullah University, Habib Ganj, Bhopal, Madhya Pradesh 462026, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raju","family":"Khan","sequence":"additional","affiliation":[{"name":"1Industrial Waste Utilization, Nano and Biomaterials, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal 462026, MP, India"},{"name":"3Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajeet","family":"Kaushik","sequence":"additional","affiliation":[{"name":"4NanoBioTech Laboratory, Department of Environmental Engineering, Florida Polytechnic University, Lakeland, FL 33805, U.S.A."},{"name":"5School of Engineering, University of Petroleum and Energy Studies, Dehradun 248007, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3958-5002","authenticated-orcid":false,"given":"Ebrahim","family":"Mostafavi","sequence":"additional","affiliation":[{"name":"6Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, U.S.A."},{"name":"7Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","published-online":{"date-parts":[[2023,7,26]]},"reference":[{"key":"2023072615005225100_B1","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.clinimag.2020.05.013","article-title":"Extrapulmonary manifestations of COVID-19: Radiologic and clinical overview","volume":"66","author":"Behzad","year":"2020","journal-title":"Clin. Imaging"},{"key":"2023072615005225100_B2","doi-asserted-by":"publisher","first-page":"7326","DOI":"10.1021\/acsabm.0c01083","article-title":"Point-of-care biosensor-based diagnosis of COVID-19 holds promise to combat current and future pandemics","volume":"3","author":"Parihar","year":"2020","journal-title":"ACS Appl. Bio. Mater."},{"key":"2023072615005225100_B3","doi-asserted-by":"publisher","first-page":"2126","DOI":"10.1016\/S0140-6736(21)02758-6","article-title":"Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic","volume":"398","author":"Karim","year":"2021","journal-title":"Lancet North Am. Ed."},{"key":"2023072615005225100_B4","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-021-03564-6","article-title":"Daily briefing: Omicron coronavirus variant puts scientists on alert","author":"Graham","year":"2021","journal-title":"Nature"},{"key":"2023072615005225100_B5","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1002\/mco2.110","article-title":"SARS-CoV-2 Omicron variant: Characteristics and prevention","volume":"2","author":"He","year":"2021","journal-title":"MedComm. (Beijing)"},{"key":"2023072615005225100_B6","doi-asserted-by":"publisher","first-page":"e119","DOI":"10.1002\/mco2.119","article-title":"SARS-CoV-2 Omicron variant: A next phase of the COVID-19 pandemic and a call to arms for system sciences and precision medicine","volume":"3","author":"Mostafavi","year":"2022","journal-title":"MedComm (Beijing)"},{"key":"2023072615005225100_B7","doi-asserted-by":"publisher","first-page":"5","DOI":"10.3389\/fnano.2020.571284","article-title":"Grand Challenges in Bio-Nanotechnology to Manage the COVID-19 Pandemic","author":"Paliwal","year":"2020","journal-title":"Front. Nanotechnol."},{"key":"2023072615005225100_B8","doi-asserted-by":"publisher","first-page":"7306","DOI":"10.1021\/acsabm.0c01004","article-title":"Electrochemical SARS-CoV-2 Sensing at Point-of-Care and Artificial Intelligence for Intelligent COVID-19 Management","volume":"3","author":"Kaushik","year":"2020","journal-title":"ACS Appl. Bio. Mater."},{"key":"2023072615005225100_B9","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1039\/D1TB02277F","article-title":"Borophene as an emerging 2D flatland for biomedical applications: current challenges and future prospects","volume":"10","author":"Mater","year":"2022","journal-title":"J. Mater. Chem. B."},{"key":"2023072615005225100_B10","doi-asserted-by":"publisher","first-page":"131089","DOI":"10.1016\/j.matlet.2021.131089","article-title":"Perspectives on 2D-borophene flatland for smart bio-sensing","volume":"308","author":"Kumar Sharma","year":"2022","journal-title":"Mater. Lett."},{"key":"2023072615005225100_B11","doi-asserted-by":"publisher","first-page":"111993","DOI":"10.1016\/j.rser.2021.111993","article-title":"Graphene quantum dots: A contemporary perspective on scope, opportunities, and sustainability","volume":"157","author":"Kumar","year":"2022","journal-title":"Renewable Sustainable Energy Rev."},{"key":"2023072615005225100_B12","doi-asserted-by":"publisher","first-page":"130898","DOI":"10.1016\/j.matlet.2021.130898","article-title":"High throughput molecularly imprinted polymers based electrochemical nanosensors for point-of-care diagnostics of COVID-19","volume":"306","author":"Singhal","year":"2022","journal-title":"Mater. Lett."},{"key":"2023072615005225100_B13","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s40883-021-00219-w","article-title":"3D Printing: Advancement in Biogenerative Engineering to Combat Shortage of Organs and Bioapplicable Materials n.d","volume":"8","author":"Parihar","year":"2022","journal-title":"Regen Eng Transl Med."},{"key":"2023072615005225100_B14","doi-asserted-by":"publisher","first-page":"e10481","DOI":"10.1002\/btm2.10481","article-title":"Internet-of-medical-things integrated point-of-care biosensing devices for infectious diseases: Toward better preparedness for futuristic pandemics","author":"Parihar","year":"2023","journal-title":"Bioeng. Transl. Med."},{"key":"2023072615005225100_B15","doi-asserted-by":"publisher","first-page":"100281","DOI":"10.1016\/j.biosx.2022.100281","article-title":"Biosensors based detection of novel biomarkers associated with COVID-19: Current progress and future promise","volume":"12","author":"Pal","year":"2022","journal-title":"Biosens. Bioelectron X"},{"key":"2023072615005225100_B16","first-page":"1","article-title":"Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection","volume-title":"Revolutionary Strategies to Combat Pandemics","author":"Parihar","year":"2022"},{"key":"2023072615005225100_B17","doi-asserted-by":"publisher","first-page":"2669","DOI":"10.1002\/bit.28166","article-title":"3D printed human organoids: High throughput system for drug screening and testing in current COVID-19 pandemic","volume":"119","author":"Parihar","year":"2022","journal-title":"Biotechnol. Bioeng."},{"key":"2023072615005225100_B18","doi-asserted-by":"publisher","first-page":"2046","DOI":"10.1021\/acsabm.1c01320","article-title":"Microfluidics-Based Point-of-Care Testing (POCT) Devices in Dealing with Waves of COVID-19 Pandemic: The Emerging Solution","volume":"5","author":"Kumar","year":"2022","journal-title":"ACS Appl. Bio. Mater."},{"key":"2023072615005225100_B19","doi-asserted-by":"publisher","first-page":"8992","DOI":"10.1039\/D0TB01559H","article-title":"Core-shell nanostructures: perspectives towards drug delivery applications","volume":"8","author":"Kumar","year":"2020","journal-title":"J. Mater. Chem. B."},{"key":"2023072615005225100_B20","doi-asserted-by":"publisher","first-page":"100363","DOI":"10.1016\/j.cobme.2021.100363","article-title":"Antibacterial and antiviral high-performance nanosystems to mitigate new SARS-CoV-2 variants of concern","volume":"21","author":"Tiwari","year":"2022","journal-title":"Curr. Opin. Biomed. Eng."},{"key":"2023072615005225100_B21","doi-asserted-by":"publisher","first-page":"102229","DOI":"10.1016\/j.bcab.2021.102229","article-title":"Anti-bacterial efficacy of bio-fabricated silver nanoparticles of aerial part of Moringa oleifera lam: Rapid green synthesis, In-Vitro and In-Silico screening","volume":"39","author":"Neupane","year":"2022","journal-title":"Biocatal. Agric Biotechnol."},{"key":"2023072615005225100_B22","doi-asserted-by":"publisher","first-page":"69","DOI":"10.4103\/2230-8210.107856","article-title":"Autoimmune thyroid disorders in hepatitis C virus infection: Effect of interferon therapy","volume":"17","author":"Jadali","year":"2013","journal-title":"Indian J. Endocrinol. Metab."},{"key":"2023072615005225100_B23","doi-asserted-by":"publisher","first-page":"375","DOI":"10.4183\/aeb.2020.375","article-title":"COVID- 19 and thyroid infection: learning the lessons of the past","volume":"16","author":"Jadali","year":"2020","journal-title":"Acta. Endocrinol. (Buchar)"},{"article-title":"Coronavirus disease (COVID-19) n.d","key":"2023072615005225100_B24"},{"author":"WHO","article-title":"Coronavirus (COVID-19) Dashboard | WHO Coronavirus (COVID-19) Dashboard With Vaccination Data n.d","key":"2023072615005225100_B25"},{"key":"2023072615005225100_B26","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"A Novel Coronavirus from Patients with Pneumonia in China, 2019","volume":"382","author":"Zhu","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"2023072615005225100_B27","doi-asserted-by":"publisher","first-page":"271.e8","DOI":"10.1016\/j.cell.2020.02.052","article-title":"SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor","volume":"181","author":"Hoffmann","year":"2020","journal-title":"Cell"},{"key":"2023072615005225100_B28","doi-asserted-by":"publisher","first-page":"1016.e19","DOI":"10.1016\/j.cell.2020.04.035","article-title":"SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues","volume":"181","author":"Ziegler","year":"2020","journal-title":"Cell"},{"key":"2023072615005225100_B29","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet North Am. Ed."},{"key":"2023072615005225100_B30","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1089\/thy.2010.0429","article-title":"Thyroid hormones as modulators of immune activities at the cellular level","volume":"21","author":"De Vito","year":"2011","journal-title":"Thyroid"},{"key":"2023072615005225100_B31","first-page":"107","article-title":"Infection, thyroid disease, and autoimmunity","volume":"14","author":"Tomer","year":"1993","journal-title":"Endocr. Rev."},{"key":"2023072615005225100_B32","doi-asserted-by":"publisher","first-page":"1250","DOI":"10.1210\/er.2018-00170","article-title":"The Aging Thyroid: A Reappraisal Within the Geroscience Integrated Perspective","volume":"40","author":"Franceschi","year":"2019","journal-title":"Endocr. Rev."},{"key":"2023072615005225100_B33","doi-asserted-by":"publisher","first-page":"104146","DOI":"10.1016\/j.jff.2020.104146","article-title":"Phytochemicals containing biologically active polyphenols as an effective agent against Covid-19-inducing coronavirus","volume":"73","author":"Chojnacka","year":"2020","journal-title":"J. Funct. Foods"},{"key":"2023072615005225100_B34","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/S2225-4110(16)30055-4","article-title":"Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication","volume":"1","author":"Wen","year":"2011","journal-title":"J. Tradit. Complement Med."},{"key":"2023072615005225100_B35","article-title":"Phytochemicals based therapeutic approaches for Breast cancer targeting: Molecular docking study","author":"Parihar","year":"2022","journal-title":"chemrxiv.org"},{"key":"2023072615005225100_B36","doi-asserted-by":"crossref","first-page":"105468","DOI":"10.1016\/j.compbiomed.2022.105468","article-title":"Phytochemicals-based targeting RdRp and main protease of SARS-CoV-2 using docking and steered molecular dynamic simulation: A promising therapeutic approach for Tackling COVID-19","author":"Parihar","year":"2022","journal-title":"Comput. Biol. Med."},{"key":"2023072615005225100_B37","doi-asserted-by":"publisher","DOI":"10.21203\/rs.3.rs-1242644\/v1","article-title":"In silico analysis for the repurposing of broad-spectrum antiviral drugs against multiple targets from SARS-CoV-2: A molecular docking and ADMET approach","author":"Parihar","year":"2022"},{"key":"2023072615005225100_B38","first-page":"1250","article-title":"The Aging Thyroid: A Reappraisal Within the Geroscience Integrated Perspective","volume":"40","author":"Franceschi","year":"2019","journal-title":"Endocr. Rev."},{"key":"2023072615005225100_B39","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1056\/NEJMoa2015432","article-title":"Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19","volume":"383","author":"Ackermann","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"2023072615005225100_B40","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/nrendo.2018.18","article-title":"Global epidemiology of hyperthyroidism and hypothyroidism","volume":"14","author":"Taylor","year":"2018","journal-title":"Nat. Rev. Endocrinol."},{"key":"2023072615005225100_B41","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s12020-020-02364-8","article-title":"Thyroid disease in the time of COVID-19","volume":"68","author":"Dworakowska","year":"2020","journal-title":"Endocrine"},{"key":"2023072615005225100_B42","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s11154-020-09615-z","article-title":"Impact of COVID-19 on the thyroid gland: an update","volume":"22","author":"Scappaticcio","year":"2021","journal-title":"Rev. Endocr. Metab. Disord."},{"key":"2023072615005225100_B43","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1007\/s40618-021-01554-z","article-title":"Thyroid and COVID-19: a review on pathophysiological, clinical and organizational aspects","volume":"44","author":"Lisco","year":"2021","journal-title":"J. Endocrinol. Invest."},{"key":"2023072615005225100_B44","doi-asserted-by":"crossref","first-page":"e05712","DOI":"10.1016\/j.heliyon.2020.e05712","article-title":"Prospective role of thyroid disorders in monitoring COVID-19 pandemic","volume":"6","author":"Kumari","year":"2020","journal-title":"Heliyon"},{"key":"2023072615005225100_B45","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1507\/endocrj.EJ20-0443","article-title":"Thyroid complications of SARS and coronavirus disease 2019 (COVID-19)","volume":"68","author":"Speer","year":"2021","journal-title":"Endocr. J."},{"key":"2023072615005225100_B46","doi-asserted-by":"publisher","first-page":"196989","DOI":"10.1016\/j.virusres.2020.197989","article-title":"Natural product-derived phytochemicals as potential agents against coronaviruses: A review","volume":"284","author":"Mani","year":"2020","journal-title":"Virus Res."},{"key":"2023072615005225100_B47","doi-asserted-by":"publisher","first-page":"1744","DOI":"10.3389\/fphar.2020.588467","article-title":"Phytochemicals: Potential Therapeutic Interventions Against Coronavirus-Associated Lung Injury","volume":"11","author":"Majnooni","year":"2020","journal-title":"Front Pharmacol."},{"key":"2023072615005225100_B48","doi-asserted-by":"publisher","first-page":"2169","DOI":"10.1007\/s11224-022-02035-6","article-title":"Phytovid19: a compilation of phytochemicals research in coronavirus","volume":"33","author":"Bhargav","year":"2022","journal-title":"Struct. Chem."},{"key":"2023072615005225100_B49","first-page":"1","article-title":"Advances in understanding the renin-angiotensin-aldosterone system (RAAS) in blood pressure control and recent pivotal trials of RAAS blockade in heart failure and diabetic nephropathy","volume":"6","author":"Drawz","year":"2017","journal-title":"F1000Res."},{"key":"2023072615005225100_B50","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/256294","article-title":"Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease","volume":"2012","author":"Tikellis","year":"2012","journal-title":"Int. J. Pept."},{"key":"2023072615005225100_B51","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1038\/s41581-020-0279-4","article-title":"Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic","volume":"16","author":"South","year":"2020","journal-title":"Nat. Rev. Nephrol."},{"key":"2023072615005225100_B52","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1038\/s41580-021-00418-x","article-title":"Mechanisms of SARS-CoV-2 entry into cells","volume":"23","author":"Jackson","year":"2022","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"2023072615005225100_B53","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1126\/sciadv.abe0751","article-title":"Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L","volume":"6","author":"Sacco","year":"2020","journal-title":"Sci. Adv."},{"key":"2023072615005225100_B54","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1016\/j.apsb.2021.06.016","article-title":"Recent advances in developing small-molecule inhibitors against SARS-CoV-2","volume":"12","author":"Xiang","year":"2022","journal-title":"Acta Pharm. Sin B."},{"key":"2023072615005225100_B55","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1183\/13993003.00912-2020","article-title":"Understanding the renin-angiotensin-aldosterone-SARS-CoV axis: a comprehensive review","volume":"56","author":"Ingraham","year":"2020","journal-title":"Eur. Respir. J."},{"key":"2023072615005225100_B56","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.hrtlng.2020.08.024","article-title":"The association of D-dimers with mortality, intensive care unit admission or acute respiratory distress syndrome in patients hospitalized with coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis","volume":"50","author":"Bansal","year":"2021","journal-title":"Heart Lung"},{"key":"2023072615005225100_B57","doi-asserted-by":"publisher","first-page":"1","DOI":"10.15420\/ecr.2020.30","article-title":"The renin-angiotensin-aldosterone system and coronavirus disease 2019","volume":"16","author":"Coto","year":"2021","journal-title":"Eur. Cardiol."},{"key":"2023072615005225100_B58","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1161\/HYPERTENSIONAHA.120.15082","article-title":"Renin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers","volume":"75","author":"Danser","year":"2020","journal-title":"Hypertension"},{"key":"2023072615005225100_B59","doi-asserted-by":"publisher","first-page":"104350","DOI":"10.1016\/j.yexmp.2019.104350","article-title":"ACE2 exhibits protective effects against LPS-induced acute lung injury in mice by inhibiting the LPS-TLR4 pathway","volume":"113","author":"Ye","year":"2020","journal-title":"Exp. Mol. Pathol."},{"key":"2023072615005225100_B60","doi-asserted-by":"publisher","first-page":"3085","DOI":"10.1016\/j.jacc.2020.04.028","article-title":"Clinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System: JACC Review Topic of the Week","volume":"75","author":"Brojakowska","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"2023072615005225100_B61","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1111\/jth.14849","article-title":"Thromboinflammation and the hypercoagulability of COVID-19","volume":"18","author":"Connors","year":"2020","journal-title":"J. Thromb. Haemost."},{"key":"2023072615005225100_B62","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1111\/jth.14781","article-title":"Disseminated intravascular coagulation in patients with 2019-nCoV pneumonia","volume":"18","author":"Lillicrap","year":"2020","journal-title":"J. Thromb. Haemost."},{"key":"2023072615005225100_B63","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.thromres.2015.12.008","article-title":"The acute prothrombotic effect of aldosterone in rats is partially mediated via angiotensin II receptor type 1","volume":"138","author":"Gromotowicz-Poplawska","year":"2016","journal-title":"Thromb. Res."},{"key":"2023072615005225100_B64","doi-asserted-by":"publisher","first-page":"3867","DOI":"10.1210\/jc.2003-030374","article-title":"Effect of combined AT1 receptor and aldosterone receptor antagonism on plasminogen activator inhibitor-1","volume":"88","author":"Sawathiparnich","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2023072615005225100_B65","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.bbrc.2008.05.185","article-title":"Aldosterone modifies hemostasis via upregulation of the protein-C receptor in human vascular endothelium","volume":"373","author":"Ducros","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"2023072615005225100_B66","doi-asserted-by":"publisher","first-page":"13","DOI":"10.33549\/physiolres.931525","article-title":"The role of renin-angiotensin system in prothrombotic state in essential hypertension","volume":"59","author":"Remkov\u00e1","year":"2010","journal-title":"Physiol. Res."},{"key":"2023072615005225100_B67","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1111\/andr.12836","article-title":"Worse progression of COVID-19 in men: Is testosterone a key factor?","volume":"9","author":"Giagulli","year":"2021","journal-title":"Andrology"},{"key":"2023072615005225100_B68","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1002\/jmv.26259","article-title":"Evaluation of sex-related hormones and semen characteristics in reproductive-aged male COVID-19 patients","volume":"93","author":"Ma","year":"2021","journal-title":"J. Med. Virol."},{"key":"2023072615005225100_B69","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1111\/andr.12821","article-title":"Low testosterone levels predict clinical adverse outcomes in SARS-CoV-2 pneumonia patients","volume":"9","author":"Rastrelli","year":"2021","journal-title":"Andrology"},{"key":"2023072615005225100_B70","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1111\/andr.12836","article-title":"Worse progression of COVID-19 in men: Is testosterone a key factor?","volume":"9","author":"Giagulli","year":"2021","journal-title":"Andrology"},{"key":"2023072615005225100_B71","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5534\/wjmh.200134","article-title":"Male Fertility and the COVID-19 Pandemic: Systematic Review of the Literature","volume":"38","author":"Khalili","year":"2020","journal-title":"World J. Mens. Health"},{"key":"2023072615005225100_B72","doi-asserted-by":"publisher","first-page":"bqaa127","DOI":"10.1210\/endocr\/bqaa127","article-title":"Estradiol, Progesterone, Immunomodulation, and COVID-19 Outcomes","volume":"161","author":"Mauvais-Jarvis","year":"2020","journal-title":"Endocrinology"},{"key":"2023072615005225100_B73","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1172\/jci.insight.131774","article-title":"Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection","volume":"4","author":"Kulcsar","year":"2019","journal-title":"JCI Insight"},{"key":"2023072615005225100_B74","first-page":"37","article-title":"Acute Vision Loss in a Patient with COVID-19","volume":"06","author":"Selvaraj","journal-title":"medRxiv"},{"key":"2023072615005225100_B75","first-page":"168","article-title":"DS- of pharmacognosy and, 2013 undefined. Phytochemistry of medicinal plants","volume":"1","author":"Saxena","year":"2013","journal-title":"PhytojournalCom"},{"key":"2023072615005225100_B76","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/0305-1978(93)90098-C","article-title":"Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants","volume":"21","author":"Waterman","year":"1993","journal-title":"Biochem. Syst. Ecol."},{"key":"2023072615005225100_B77","doi-asserted-by":"publisher","first-page":"384S","DOI":"10.3945\/an.112.003517","article-title":"Health-promoting components of fruits and vegetables in the diet","volume":"3","author":"Liu","year":"2013","journal-title":"Adv. Nutr."},{"key":"2023072615005225100_B78","doi-asserted-by":"publisher","first-page":"1744","DOI":"10.3389\/fphar.2020.588467","article-title":"Phytochemicals: Potential Therapeutic Interventions Against Coronavirus-Associated Lung Injury","volume":"11","author":"Majnooni","year":"2020","journal-title":"Front. Pharmacol."},{"key":"2023072615005225100_B79","doi-asserted-by":"publisher","first-page":"433","DOI":"10.3390\/covid2040031","article-title":"A Randomised, Double-Blind, Placebo-Controlled Trial Evaluating Concentrated Phytochemical-Rich Nutritional Capsule in Addition to a Probiotic Capsule on Clinical Outcomes among Individuals with COVID-19\u2014The UK Phyto-V Study","volume":"2","author":"Thomas","year":"2022","journal-title":"COVID"},{"key":"2023072615005225100_B80","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1007\/s13337-021-00706-2","article-title":"Efficacy of phytochemicals as immunomodulators in managing COVID-19: a comprehensive view","volume":"32","author":"Bhattacharya","year":"2021","journal-title":"Virusdisease"},{"key":"2023072615005225100_B81","doi-asserted-by":"publisher","DOI":"10.20944\/preprints202003.0455.v1","article-title":"Eucalyptol (1, 8 cineole) from eucalyptus essential oil a potential inhibitor of COVID 19 corona virus infection by molecular docking studies","author":"Dev Sharma","year":"2020","journal-title":"Preprints.org 2020"},{"key":"2023072615005225100_B82","doi-asserted-by":"crossref","first-page":"197989","DOI":"10.1016\/j.virusres.2020.197989","article-title":"Natural product-derived phytochemicals as potential agents against coronaviruses: A review","volume":"284","author":"Mani","year":"2020","journal-title":"Virus Res."},{"key":"2023072615005225100_B83","doi-asserted-by":"crossref","first-page":"147","DOI":"10.2174\/187221312800166886","article-title":"Phytochemicals to prevent inflammation and allergy","volume":"6","author":"Bellik","year":"2012","journal-title":"Recent Pat. Inflamm Allergy Drug Discov."},{"key":"2023072615005225100_B84","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/576479","article-title":"Potential effects of medicinal plants and secondary metabolites on acute lung injury","volume":"2013","author":"Corn\u00e9lio Favarin","year":"2013","journal-title":"Biomed. Res. Int."},{"key":"2023072615005225100_B85","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1016\/j.apsb.2021.10.026","article-title":"Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays","volume":"12","author":"Ma","year":"2022","journal-title":"Acta Pharm. Sin. B"},{"key":"2023072615005225100_B86","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1007\/s00044-022-02903-0","article-title":"Invalidation of dieckol and 1,2,3,4,6-pentagalloylglucose (PGG) as SARS-CoV-2 main protease inhibitors and the discovery of PGG as a papain-like protease inhibitor","volume":"31","author":"Tan","year":"2022","journal-title":"Med. Chem. Res."},{"key":"2023072615005225100_B87","doi-asserted-by":"crossref","first-page":"4362","DOI":"10.1080\/07391102.2020.1779818","article-title":"Evaluation of green tea polyphenols as novel corona virus (SARS CoV-2) main protease (Mpro) inhibitors - an in silico docking and molecular dynamics simulation study","volume":"39","author":"Ghosh","year":"2021","journal-title":"J. Biomol. Struct. Dyn."},{"key":"2023072615005225100_B88","doi-asserted-by":"crossref","first-page":"5948","DOI":"10.1021\/acs.jafc.1c02050","article-title":"Epigallocatechin Gallate Inhibits the Uridylate-Specific Endoribonuclease Nsp15 and Efficiently Neutralizes the SARS-CoV-2 Strain","volume":"69","author":"Hong","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"2023072615005225100_B89","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3390\/md18040225","article-title":"Putative Inhibitors of SARS-CoV-2 Main Protease from A Library of Marine Natural Products: A Virtual Screening and Molecular Modeling Study","volume":"18","author":"Gentile","year":"2020","journal-title":"Mar. Drugs"},{"key":"2023072615005225100_B90","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1002\/ptr.6887","article-title":"A role for quercetin in coronavirus disease 2019 (COVID-19)","volume":"35","author":"Derosa","year":"2021","journal-title":"Phytother. Res."},{"key":"2023072615005225100_B91","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms21145171","article-title":"Protective Effect of Epigallocatechin-3-Gallate (EGCG) in Diseases with Uncontrolled Immune Activation: Could Such a Scenario Be Helpful to Counteract COVID-19?","volume":"21","author":"Menegazzi","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"2023072615005225100_B92","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.virol.2021.01.015","article-title":"Exploring the efficacy of naturally occurring biflavone based antioxidants towards the inhibition of the SARS-CoV-2 spike glycoprotein mediated membrane fusion","volume":"556","author":"Mondal","year":"2021","journal-title":"Virology"},{"key":"2023072615005225100_B93","doi-asserted-by":"publisher","first-page":"299","DOI":"10.3390\/molecules22020299","article-title":"A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid","volume":"22","author":"Yu","year":"2017","journal-title":"Molecules"},{"key":"2023072615005225100_B94","doi-asserted-by":"publisher","first-page":"11334","DOI":"10.1128\/JVI.78.20.11334-11339.2004","article-title":"Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells","volume":"78","author":"Yi","year":"2004","journal-title":"J. Virol."},{"key":"2023072615005225100_B95","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1007\/s13659-020-00253-1","article-title":"Recognition of Natural Products as Potential Inhibitors of COVID-19 Main Protease (Mpro): In-Silico Evidences","volume":"10","author":"Narkhede","year":"2020","journal-title":"Nat. Prod. Bioprospect"},{"key":"2023072615005225100_B96","doi-asserted-by":"publisher","first-page":"105995","DOI":"10.1016\/j.ijantimicag.2020.105995","article-title":"Pharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19","volume":"55","author":"Luo","year":"2020","journal-title":"Int. J. Antimicrob. Agents"},{"key":"2023072615005225100_B97","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1007\/s13659-020-00253-1","article-title":"Recognition of Natural Products as Potential Inhibitors of COVID-19 Main Protease (Mpro): In-Silico Evidences","volume":"10","author":"Narkhede","year":"2020","journal-title":"Nat. Prod. Bioprospect"},{"key":"2023072615005225100_B98","doi-asserted-by":"publisher","first-page":"2707","DOI":"10.3390\/molecules25112707","article-title":"Potential of flavonoid-inspired phytomedicines against COVID-19","volume":"25","author":"Ngwa","year":"2020","journal-title":"Molecules"},{"key":"2023072615005225100_B99","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s12672-020-00382-6","article-title":"Baicalein is a phytohormone that signals through the progesterone and glucocorticoid receptors","volume":"11","author":"Austin","year":"2020","journal-title":"Horm. Cancer"},{"key":"2023072615005225100_B100","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1177\/1934578X1200700413","article-title":"Chemical constituents of the aerial parts of Scutellaria lateriflora and their \u03b1-glucosidase inhibitory activities","volume":"7","author":"Kuroda","year":"2012","journal-title":"Nat. Prod. Commun."},{"key":"2023072615005225100_B101","doi-asserted-by":"publisher","first-page":"5215","DOI":"10.1002\/fsn3.1858","article-title":"Curcumin (a constituent of turmeric): New treatment option against COVID-19","volume":"8","author":"Babaei","year":"2020","journal-title":"Food Sci. Nutr."},{"key":"2023072615005225100_B102","doi-asserted-by":"publisher","first-page":"912","DOI":"10.3389\/fmicb.2019.00912","article-title":"Anti-infective Properties of the Golden Spice Curcumin","volume":"10","author":"Praditya","year":"2019","journal-title":"Front. Microbiol."},{"key":"2023072615005225100_B103","first-page":"1","article-title":"Kolaviron (Kolaflavanone), apigenin, fisetin as potential Coronavirus inhibitors: In silico investigation","author":"Oladele","journal-title":"Preprint N.d."},{"key":"2023072615005225100_B104","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1007\/s10529-011-0845-8","article-title":"Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris","volume":"34","author":"Nguyen","year":"2012","journal-title":"Biotechnol. Lett"},{"key":"2023072615005225100_B105","doi-asserted-by":"publisher","first-page":"7940","DOI":"10.1016\/j.bmc.2010.09.035","article-title":"Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition","volume":"18","author":"Ryu","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"2023072615005225100_B106","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.bbrc.2021.02.016","article-title":"EGCG, a green tea polyphenol, inhibits human coronavirus replication in vitro","volume":"547","author":"Jang","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"2023072615005225100_B107","doi-asserted-by":"publisher","first-page":"1574","DOI":"10.1099\/jgv.0.001574","article-title":"The green tea catechin epigallocatechin gallate inhibits SARS-CoV-2 infection","volume":"102","author":"Henss","year":"2021","journal-title":"J. Gen. Virol."},{"key":"2023072615005225100_B108","doi-asserted-by":"publisher","first-page":"e0245209","DOI":"10.1371\/journal.pone.0245209","article-title":"Quercetin as a potential treatment for COVID-19-induced acute kidney injury: Based on network pharmacology and molecular docking study","volume":"16","author":"Gu","year":"2021","journal-title":"PloS ONE"},{"key":"2023072615005225100_B109","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1007\/s10529-011-0845-8","article-title":"Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris","volume":"34","author":"Nguyen","year":"2012","journal-title":"Biotechnol. Lett"},{"key":"2023072615005225100_B110","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-021-96963-8","article-title":"Revealing the molecular interplay of curcumin as Culex pipiens Acetylcholine esterase 1 (AChE1) inhibitor","volume":"11","author":"Rao","year":"2021","journal-title":"Sci. Rep."},{"key":"2023072615005225100_B111","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1038\/s41586-020-2223-y","article-title":"Structure of M pro from SARS-CoV-2 and discovery of its inhibitors","volume":"582","author":"Jin","year":"2020","journal-title":"Nature"},{"key":"2023072615005225100_B112","doi-asserted-by":"publisher","first-page":"107325","DOI":"10.1016\/j.compbiolchem.2020.107325","article-title":"Virtual screening of approved drugs as potential SARS-CoV-2 main protease inhibitors","volume":"88","author":"Jim\u00e9nez-Alberto","year":"2020","journal-title":"Comput. Biol. Chem."},{"key":"2023072615005225100_B113","doi-asserted-by":"publisher","first-page":"3147","DOI":"10.1111\/bph.15092","article-title":"Potential therapeutic targets and promising drugs for combating SARS-CoV-2","volume":"177","author":"Zhou","year":"2020","journal-title":"Br. J. Pharmacol."},{"key":"2023072615005225100_B114","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1002\/jmv.25726","article-title":"Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2","volume":"92","author":"Liu","year":"2020","journal-title":"J. Med. Virol."},{"key":"2023072615005225100_B115","doi-asserted-by":"publisher","first-page":"104904","DOI":"10.1016\/j.phrs.2020.104904","article-title":"The possible mechanisms of action of 4-aminoquinolines (chloroquine\/hydroxychloroquine) against Sars-Cov-2 infection (COVID-19): A role for iron homeostasis?","volume":"158","author":"Quiros Roldan","year":"2020","journal-title":"Pharmacol. Res."},{"key":"2023072615005225100_B116","doi-asserted-by":"publisher","first-page":"3147","DOI":"10.1111\/bph.15092","article-title":"Potential therapeutic targets and promising drugs for combating SARS-CoV-2","volume":"177","author":"Zhou","year":"2020","journal-title":"Br. J. Pharmacol."},{"key":"2023072615005225100_B117","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/S2225-4110(16)30055-4","article-title":"Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication","volume":"1","author":"Wen","year":"2011","journal-title":"J. Tradit. Complement Med."},{"key":"2023072615005225100_B118","doi-asserted-by":"publisher","first-page":"1775","DOI":"10.3390\/molecules26061775","article-title":"Medicinal plants, phytochemicals, and herbs to combat viral pathogens including SARS-CoV-2","volume":"26","author":"Anand","year":"2021","journal-title":"Molecules"},{"key":"2023072615005225100_B119","doi-asserted-by":"publisher","first-page":"7561","DOI":"10.1021\/acs.jmedchem.2c00303","article-title":"Progress and challenges in targeting the SARS-CoV-2 papain-like protease","volume":"65","author":"Tan","year":"2022","journal-title":"J. Med. Chem."},{"key":"2023072615005225100_B120","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1056\/NEJMoa2015432","article-title":"Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19","volume":"383","author":"Ackermann","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"2023072615005225100_B121","doi-asserted-by":"publisher","first-page":"E803","DOI":"10.1210\/clinem\/dgaa830","article-title":"Thyroid function before, during, and after COVID-19","volume":"106","author":"Khoo","year":"2021","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2023072615005225100_B122","doi-asserted-by":"publisher","first-page":"E926","DOI":"10.1210\/clinem\/dgaa813","article-title":"Thyroid dysfunction in relation to immune profile, disease status, and outcome in 191 Patients with COVID-19","volume":"106","author":"Lui","year":"2021","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2023072615005225100_B123","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/B978-0-323-91172-6.00017-0","article-title":"Natural products as a therapy to combat against SARS-CoV-2 virus infection","author":"Malviya","year":"2022)","journal-title":"Academic Press."},{"key":"2023072615005225100_B124","doi-asserted-by":"crossref","first-page":"532","DOI":"10.4103\/ijem.IJEM_779_20","article-title":"Thyroid Function Test in COVID-19 Patients: A Cross-Sectional Study in a Tertiary Care Hospital","volume":"24","author":"Sen","year":"2020","journal-title":"Indian J. Endocrinol. Metab."},{"key":"2023072615005225100_B125","doi-asserted-by":"crossref","first-page":"e14129","DOI":"10.1111\/ijcp.14129","article-title":"The prognostic impact of thyroid disorders on the clinical severity of COVID-19: Results of single-centre pandemic hospital","volume":"75","author":"G\u00fcven","year":"2021","journal-title":"Int. J. Clin. Pract."},{"key":"2023072615005225100_B126","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/8891539","article-title":"Subacute Thyroiditis Associated with COVID-19","volume":"2020","author":"Campos-Barrera","year":"2020","journal-title":"Case Rep. Endocrinol."},{"key":"2023072615005225100_B127","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1007\/s40618-020-01312-7","article-title":"SARS-CoV-2: a potential trigger for subacute thyroiditis? Insights from a case report","volume":"43","author":"Ippolito","year":"2020","journal-title":"J. Endocrinol. Invest."},{"key":"2023072615005225100_B128","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1210\/clinem\/dgaa276","article-title":"Subacute Thyroiditis After Sars-COV-2 Infection","volume":"105","author":"Brancatella","year":"2020","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2023072615005225100_B129","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s42000-020-00230-w","article-title":"Subacute thyroiditis in a patient infected with SARS-COV-2: an endocrine complication linked to the COVID-19 pandemic","volume":"20","author":"Ruggeri","year":"2021","journal-title":"Hormones (Athens)"},{"key":"2023072615005225100_B130","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S2213-8587(20)30266-7","article-title":"SARS-CoV-2-related atypical thyroiditis","volume":"8","author":"Muller","year":"2020","journal-title":"Lancet Diab. Endocrinol."},{"key":"2023072615005225100_B131","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1007\/s40618-020-01312-7","article-title":"SARS-CoV-2: a potential trigger for subacute thyroiditis? Insights from a case report","volume":"43","author":"Ippolito","year":"2020","journal-title":"J. Endocrinol. Invest."},{"key":"2023072615005225100_B132","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1007\/s42000-020-00230-w","article-title":"Subacute thyroiditis in a patient infected with SARS-COV-2: an endocrine complication linked to the COVID-19 pandemic","volume":"20","author":"Ruggeri","year":"2021","journal-title":"Hormones (Athens)"},{"key":"2023072615005225100_B133","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/8891539","article-title":"Subacute thyroiditis associated with COVID-19","volume":"2020","author":"Campos-Barrera","year":"2020","journal-title":"Case Rep. Endocrinol."},{"key":"2023072615005225100_B134","doi-asserted-by":"publisher","first-page":"E803","DOI":"10.1210\/clinem\/dgaa830","article-title":"Thyroid Function Before, During, and After COVID-19","volume":"106","author":"Khoo","year":"2021","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2023072615005225100_B135","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1089\/thy.2020.0363","article-title":"Thyroid Function Analysis in 50 Patients with COVID-19: A Retrospective Study","volume":"31","author":"Chen","year":"2021","journal-title":"Thyroid"},{"key":"2023072615005225100_B136","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1007\/s40618-020-01460-w","article-title":"Thyroid hormone concentrations in severely or critically ill patients with COVID-19","volume":"44","author":"Gao","year":"2021","journal-title":"J. Endocrinol. Invest."},{"key":"2023072615005225100_B137","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1530\/EJE-20-0335","article-title":"Thyrotoxicosis in patients with COVID-19: the THYRCOV study","volume":"183","author":"Lania","year":"2020","journal-title":"Eur. J. Endocrinol."},{"key":"2023072615005225100_B138","doi-asserted-by":"publisher","first-page":"566439","DOI":"10.3389\/fendo.2020.566439","article-title":"Euthyroid Sick Syndrome in Patients With COVID-19","volume":"11","author":"Zou","year":"2020","journal-title":"Front Endocrinol. (Lausanne)"},{"key":"2023072615005225100_B139","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1210\/jcem-67-6-1156","article-title":"Deficiency of superoxide dismutase in endemic goiter tissue","volume":"67","author":"Sugawara","year":"1988","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2023072615005225100_B140","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/S0940-2993(11)80288-5","article-title":"Subchronic application of humic acids and associated compounds provokes histological changes of goitre in the rat","volume":"47","author":"Seffner","year":"1995","journal-title":"Exp. Toxicol. Pathol."},{"key":"2023072615005225100_B141","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1038\/nrendo.2018.18","article-title":"Global epidemiology of hyperthyroidism and hypothyroidism","volume":"14","author":"Taylor","year":"2018","journal-title":"Nat. Rev. Endocrinol."},{"key":"2023072615005225100_B142","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fendo.2012.00094","article-title":"Update on genistein and thyroid: an overall message of safety","volume":"3","author":"Marini","year":"2012","journal-title":"Front Endocrinol. (Lausanne)"},{"key":"2023072615005225100_B143","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1089\/thy.2020.0363","article-title":"Thyroid Function Analysis in 50 Patients with COVID-19: A Retrospective Study","volume":"31","author":"Chen","year":"2021","journal-title":"Thyroid"},{"key":"2023072615005225100_B144","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1007\/s40618-020-01460-w","article-title":"Thyroid hormone concentrations in severely or critically ill patients with COVID-19","volume":"44","author":"Gao","year":"2021","journal-title":"J. Endocrinol. Invest."},{"key":"2023072615005225100_B145","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1530\/EJE-20-0335","article-title":"Thyrotoxicosis in patients with COVID-19: the THYRCOV study","volume":"183","author":"Lania","year":"2020","journal-title":"Eur. J. Endocrinol."},{"key":"2023072615005225100_B146","doi-asserted-by":"publisher","first-page":"566439","DOI":"10.3389\/fendo.2020.566439","article-title":"Euthyroid Sick Syndrome in Patients With COVID-19","volume":"11","author":"Zou","year":"2020","journal-title":"Front Endocrinol. (Lausanne)"},{"key":"2023072615005225100_B147","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1038\/s41586-020-2223-y","article-title":"Structure of M pro from SARS-CoV-2 and discovery of its inhibitors","volume":"582","author":"Jin","year":"2020","journal-title":"Nature"},{"key":"2023072615005225100_B148","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1210\/jcem-67-6-1156","article-title":"Deficiency of superoxide dismutase in endemic goiter tissue","volume":"67","author":"Sugawara","year":"1988","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2023072615005225100_B149","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/S0940-2993(11)80288-5","article-title":"Subchronic application of humic acids and associated compounds provokes histological changes of goitre in the rat","volume":"47","author":"Seffner","year":"1995","journal-title":"Exp. Toxicol. Pathol."},{"key":"2023072615005225100_B150","doi-asserted-by":"publisher","first-page":"e237336","DOI":"10.1136\/bcr-2020-237336","article-title":"Subacute thyroiditis associated with COVID-19","volume":"13","author":"Mattar","year":"2020","journal-title":"BMJ Case Rep."},{"key":"2023072615005225100_B151","doi-asserted-by":"publisher","first-page":"104904","DOI":"10.1016\/j.phrs.2020.104904","article-title":"The possible mechanisms of action of 4-aminoquinolines (chloroquine\/hydroxychloroquine) against Sars-Cov-2 infection (COVID-19): A role for iron homeostasis?","volume":"158","author":"Quiros Roldan","year":"2020","journal-title":"Pharmacol. Res."},{"key":"2023072615005225100_B152","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1080\/13102818.2023.2170829","article-title":"Thyroid dysfunction as a long-term post-COVID-19 complication in mild-to-moderate COVID-19","volume":"37","author":"Yanachkova","year":"2023","journal-title":"Biotechnol. Biotechnol. Equip."},{"key":"2023072615005225100_B153","first-page":"1","article-title":"Clinical presentation and prognosis of COVID-19 in older adults with hypothyroidism: data from the GeroCovid observational study","volume":"1","author":"Bagal\u00e0","year":"2023","journal-title":"J. Endocrinol. Invest."},{"key":"2023072615005225100_B154","doi-asserted-by":"publisher","DOI":"10.1530\/ETJ-22-0200","article-title":"Long-term outcome of thyroid abnormalities in patients with severe Covid-19","volume":"12","author":"Muller","year":"2023","journal-title":"Eur. Thyroid J."},{"key":"2023072615005225100_B155","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fendo.2012.00094","article-title":"Update on genistein and thyroid: an overall message of safety","volume":"3","author":"Marini","year":"2012","journal-title":"Front Endocrinol. (Lausanne)"},{"key":"2023072615005225100_B156","doi-asserted-by":"publisher","first-page":"2495","DOI":"10.1016\/j.fct.2011.06.074","article-title":"Impact of flavonoids on thyroid function","volume":"49","author":"de Souza dos Santos","year":"2011","journal-title":"Food Chem. Toxicol."},{"key":"2023072615005225100_B157","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.3390\/ijms18061247","article-title":"Flavonoids, Thyroid Iodide Uptake and Thyroid Cancer-A Review","volume":"18","author":"Gon\u00e7alves","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"2023072615005225100_B158","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/S0022-5320(79)90127-8","article-title":"Mitosis in rat thyroid epithelial cells in vivo. II. Centrioles and pericentriolar material","volume":"66","author":"Zeligs","year":"1979","journal-title":"J. Ultrastruct. Res."},{"key":"2023072615005225100_B159","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/S0022-5320(79)90125-4","article-title":"Mitosis in thyroid follicular epithelial cells in vivo. III. Cytokinesis","volume":"66","author":"Zeligs","year":"1979","journal-title":"J. Ultrastruct. Res."},{"key":"2023072615005225100_B160","doi-asserted-by":"publisher","first-page":"2743","DOI":"10.1073\/pnas.77.5.2743","article-title":"Thyrotropin preparations are mitogenic for thyroid epithelial cells in follicles in suspension culture","volume":"77","author":"Nitsch","year":"1980","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"2023072615005225100_B161","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1172\/JCI109889","article-title":"Effect of thyroid status on insulin action in rat adipocytes and skeletal muscle","volume":"66","author":"Czech","year":"1980","journal-title":"J. Clin. Invest."},{"key":"2023072615005225100_B162","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1113\/jphysiol.1965.sp007665","article-title":"Influence of the thyroid gland on the accumulation of sugars in rat intestinal mucosa during absorption","volume":"179","author":"Bronk","year":"1965","journal-title":"J. Physiol."},{"key":"2023072615005225100_B163","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.etap.2004.03.001","article-title":"The effects of low-esterified pectin on lead-induced thyroid injury in rats","volume":"17","author":"Khotimchenko","year":"2004","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"2023072615005225100_B164","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/cddiscovery.2015.47","article-title":"Inhibition of malignant thyroid carcinoma cell proliferation by Ras and galectin-3 inhibitors","volume":"1","author":"Menachem","year":"2015","journal-title":"Cell Death Discov."},{"key":"2023072615005225100_B165","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/3578402","article-title":"In Vitro and In Vivo Anti-Salmonella Evaluation of Pectin Extracts and Hydrolysates from \u201cCas Mango\u201d (Spondias dulcis)","volume":"2019","author":"Zofou","year":"2019","journal-title":"Evid Based Complement Alternat Med."},{"key":"2023072615005225100_B166","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1023\/B:BEBM.0000020205.13653.ee","article-title":"Comparative efficiency of low-esterified pectin and antistrumin during experimental hypofunction of the thyroid gland","volume":"136","author":"Khotimchenko","year":"2003","journal-title":"Bull. Exp. Biol. Med."},{"key":"2023072615005225100_B167","first-page":"4","article-title":"Free serotonin level in the blood of patients with borderline and essential hypertension","volume":"33","author":"Wocial","year":"1990","journal-title":"J. Chromatogr. B Biomed. Appl."},{"key":"2023072615005225100_B168","doi-asserted-by":"publisher","first-page":"9703","DOI":"10.1021\/acs.analchem.7b01257","article-title":"In Vivo Ambient Serotonin Measurements at Carbon-Fiber Microelectrodes","volume":"89","author":"Abdalla","year":"2017","journal-title":"Anal. Chem."},{"key":"2023072615005225100_B169","first-page":"439","article-title":"The effect of intrahypothalamic serotonin reinforcement on directional preference in rats","volume":"41","author":"Lesiecka","year":"1981","journal-title":"Acta Neurobiol. Exp. (Wars)"},{"key":"2023072615005225100_B170","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1002\/ar.21353","article-title":"Fate map of serotonin transporter-expressing cells in developing mouse thyroid","volume":"294","author":"Spina","year":"2011","journal-title":"Anat Rec. (Hoboken)"},{"article-title":"Thyroid hormone control of serotonin in developing rat brain - PubMed n.d","key":"2023072615005225100_B171"},{"key":"2023072615005225100_B172","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12974-018-1341-z","article-title":"Hashimoto's thyroiditis induces neuroinflammation and emotional alterations in euthyroid mice","volume":"15","author":"Cai","year":"2018","journal-title":"J. Neuroinflammation"},{"key":"2023072615005225100_B173","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1089\/thy.2008.0261","article-title":"Effects of selective serotonin reuptake inhibitors on thyroid function in depressed patients with primary hypothyroidism or normal thyroid function","volume":"19","author":"De Carvalho","year":"2009","journal-title":"Thyroid"},{"key":"2023072615005225100_B174","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1083\/jcb.88.3.499","article-title":"Separation of dissociated thyroid follicular and parafollicular cells: association of serotonin binding protein with parafollicular cells","volume":"88","author":"Bernd","year":"1981","journal-title":"J. Cell Biol."},{"key":"2023072615005225100_B175","first-page":"399","article-title":"Tryptophan degradation and antioxidant status in patients with thyroid disorders","volume":"21","author":"\u00dcn\u00fcvar","year":"2018","journal-title":"Arch. Iran. Med."},{"key":"2023072615005225100_B176","doi-asserted-by":"publisher","first-page":"E809","DOI":"10.1152\/ajpendo.1997.272.5.E809","article-title":"Interactions between thyroid hormone and tryptophan transport in rat liver are modulated by thyroid status","volume":"272","author":"Kemp","year":"1997","journal-title":"Am. J. Physiol."},{"key":"2023072615005225100_B177","doi-asserted-by":"publisher","first-page":"2822","DOI":"10.1210\/jc.2013-1273","article-title":"Plasmacytoid dendritic cells in patients with autoimmune thyroid disease","volume":"98","author":"Leskela","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"author":"Ritchie","article-title":"Tryptophan and iodothyronine transport interactions in HepG2 human hepatoma cells n.d","key":"2023072615005225100_B178"},{"key":"2023072615005225100_B179","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1042\/bj2810081","article-title":"Thyroid hormone concentrative uptake in rat erythrocytes. Involvement of the tryptophan transport system T in countertransport of tri-iodothyronine and aromatic amino acids","volume":"281","author":"Zhou","year":"1992","journal-title":"Biochem. J."},{"key":"2023072615005225100_B180","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.phrs.2010.05.001","article-title":"Quercetin supplementation and upper respiratory tract infection: A randomized community clinical trial","volume":"62","author":"Heinz","year":"2010","journal-title":"Pharmacol. Res."},{"key":"2023072615005225100_B181","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1002\/bdd.605","article-title":"Quercetin pharmacokinetics in humans","volume":"29","author":"Moon","year":"2008","journal-title":"Biopharm. Drug Dispos."},{"key":"2023072615005225100_B182","doi-asserted-by":"publisher","DOI":"10.1111\/jfbc.13002","article-title":"Relative protective activities of quercetin, quercetin-3-glucoside, and rutin in alcohol-induced liver injury","volume":"43","author":"Lee","year":"2019","journal-title":"J. Food Biochem."},{"key":"2023072615005225100_B183","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1007\/s13346-019-00674-7","article-title":"Characterization of a liposomal copper(II)-quercetin formulation suitable for parenteral use","volume":"10","author":"Chen","year":"2020","journal-title":"Drug Deliv. Transl. Res."},{"key":"2023072615005225100_B184","first-page":"1","article-title":"Kolaviron (Kolaflavanone), apigenin, fisetin as potential Coronavirus inhibitors: In silico investigation","author":"Oladele","journal-title":"Preprint N.d."},{"key":"2023072615005225100_B185","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1042\/bj2810081","article-title":"Thyroid hormone concentrative uptake in rat erythrocytes. Involvement of the tryptophan transport system T in countertransport of tri-iodothyronine and aromatic amino acids","volume":"281","author":"Zhou","year":"1992","journal-title":"Biochem. J."},{"key":"2023072615005225100_B186","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.phrs.2010.05.001","article-title":"Quercetin supplementation and upper respiratory tract infection: A randomized community clinical trial","volume":"62","author":"Heinz","year":"2010","journal-title":"Pharmacol. Res."},{"key":"2023072615005225100_B187","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1080\/19390211.2016.1204404","article-title":"Effect of Sesamin Supplementation on Glycemic Status, Inflammatory Markers, and Adiponectin Levels in Patients with Type 2 Diabetes Mellitus","volume":"14","author":"Mohammad Shahi","year":"2017","journal-title":"J. Diet. Suppl."},{"author":"Abd","article-title":"Effect of the Possible Role of In vivo Mobilization of Bone Marrow Stem Cells and Sesame Oil on Induced Hypothyroidism in Adult Female Albino Rats n.d","key":"2023072615005225100_B188"},{"key":"2023072615005225100_B189","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1097\/01.md.0000123095.65294.34","article-title":"Complex drug-drug-disease interactions between amiodarone, warfarin, and the thyroid gland","volume":"83","author":"Kurnik","year":"2004","journal-title":"Medicine (Baltimore)."},{"article-title":"Problems of anticoagulation with warfarin in hyperthyroidism - PubMed n.d","key":"2023072615005225100_B190"},{"key":"2023072615005225100_B191","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1097\/MBC.0b013e3282f0981f","article-title":"Effect of methimazole on warfarin anticoagulation in a case of Graves' disease","volume":"19","author":"Akin","year":"2008","journal-title":"Blood Coagul. Fibrinolysis"},{"key":"2023072615005225100_B192","first-page":"331","article-title":"Oral Anticoagulants and Drugs Which Alter Thyroid Function","volume":"14","author":"Hansten","year":"2016"},{"key":"2023072615005225100_B193","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1001\/jama.1975.03240230039019","article-title":"Warfarin-Induced Hypoprothrombinemia: Potentiation by Hyperthyroidism","volume":"231","author":"Self","year":"1975","journal-title":"JAMA"},{"key":"2023072615005225100_B194","first-page":"4815","article-title":"Knockdown of long noncoding RNA SNHG7 inhibits the proliferation and promotes apoptosis of thyroid cancer cells by downregulating BDNF","volume":"23","author":"Wang","year":"2019","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"2023072615005225100_B195","doi-asserted-by":"publisher","first-page":"9887","DOI":"10.1002\/jcb.28271","article-title":"Delphinidin inhibits epidermal growth factor-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma cells","volume":"120","author":"Lim","year":"2019","journal-title":"J. Cell. Biochem."},{"key":"2023072615005225100_B196","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1007\/s10616-018-0246-0","article-title":"Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells","volume":"70","author":"Harada","year":"2018","journal-title":"Cytotechnology"},{"key":"2023072615005225100_B197","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/4694760","article-title":"Inhibitory Effect of Delphinidin on Oxidative Stress Induced by H 2 O 2 in HepG2 Cells","volume":"2020","author":"Xu","year":"2020","journal-title":"Oxid. Med. Cell Longev."},{"key":"2023072615005225100_B198","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.aott.2017.11.011","article-title":"Cytotoxic effects of delphinidin in human osteosarcoma cells","volume":"52","author":"Lee","year":"2018","journal-title":"Acta Orthop. Traumatol. Turc."},{"key":"2023072615005225100_B199","first-page":"5954","article-title":"RhoBTB2 (DBC2) functions as a multifunctional tumor suppressor in thyroid cancer cells via mitochondrial apoptotic pathway","volume":"8","author":"Wang","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"2023072615005225100_B200","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1055\/s-2003-42652","article-title":"Piperine lowers the serum concentrations of thyroid hormones, glucose and hepatic 5\u2019D activity in adult male mice","volume":"35","author":"Panda","year":"2003","journal-title":"Horm. Metab. Res."},{"key":"2023072615005225100_B201","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.jep.2015.01.039","article-title":"Effect of piperine on inhibition of FFA induced TLR4 mediated inflammation and amelioration of acetic acid induced ulcerative colitis in mice","volume":"164","author":"Gupta","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"2023072615005225100_B202","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1515\/JBCPP.2006.17.2.71","article-title":"Piperine, an active principle from Piper nigrum, modulates hormonal and apo lipoprotein profiles in hyperlipidemic rats","volume":"17","author":"Vijayakumar","year":"2006","journal-title":"J. Basic Clin. Physiol. Pharmacol."},{"key":"2023072615005225100_B203","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1211\/jpp.59.11.0012","article-title":"Apigenin (4\u2019,5,7-trihydroxyflavone) regulates hyperglycaemia, thyroid dysfunction and lipid peroxidation in alloxan-induced diabetic mice","volume":"59","author":"Panda","year":"2007","journal-title":"J. Pharm. Pharmacol."},{"key":"2023072615005225100_B204","doi-asserted-by":"publisher","first-page":"3464","DOI":"10.1039\/C5FO00671F","article-title":"Apigenin induces autophagic cell death in human papillary thyroid carcinoma BCPAP cells","volume":"6","author":"Zhang","year":"2015","journal-title":"Food Funct."},{"key":"2023072615005225100_B205","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.21873\/anticanres.11502","article-title":"Myricetin Induces Apoptosis of Human Anaplastic Thyroid Cancer Cells via Mitochondria Dysfunction","volume":"37","author":"Jo","year":"2017","journal-title":"Anticancer Res."},{"key":"2023072615005225100_B206","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.cbi.2019.03.031","article-title":"Effects of curcumin and its adjuvant on TPC1 thyroid cell line","volume":"305","author":"Esposito","year":"2019","journal-title":"Chem. Biol. Interact."},{"key":"2023072615005225100_B207","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12906-018-2125-9","article-title":"Effects of different extracts of curcumin on TPC1 papillary thyroid cancer cell line","volume":"18","author":"Perna","year":"2018","journal-title":"BMC Complement. Altern. Med."},{"key":"2023072615005225100_B208","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/S0022-5320(79)90125-4","article-title":"Mitosis in thyroid follicular epithelial cells in vivo. III. Cytokinesis","volume":"66","author":"Zeligs","year":"1979","journal-title":"J. Ultrastruct. Res."},{"key":"2023072615005225100_B209","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/S0022-5320(79)80065-9","article-title":"Mitosis in rat thyroid epithelial cells in vivo. I. Ultrastructural changes in cytoplasmic organelles during the mitotic cycle","volume":"66","author":"Zeligs","year":"1979","journal-title":"J. Ultrastruct. Res."},{"key":"2023072615005225100_B210","doi-asserted-by":"publisher","first-page":"2743","DOI":"10.1073\/pnas.77.5.2743","article-title":"Thyrotropin preparations are mitogenic for thyroid epithelial cells in follicles in suspension culture","volume":"77","author":"Nitsch","year":"1980","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"2023072615005225100_B211","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/S0022-5320(79)90127-8","article-title":"Mitosis in rat thyroid epithelial cells in vivo. II. Centrioles and pericentriolar material","volume":"66","author":"Zeligs","year":"1979","journal-title":"J. Ultrastruct. Res."},{"key":"2023072615005225100_B212","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1172\/JCI109889","article-title":"Effect of thyroid status on insulin action in rat adipocytes and skeletal muscle","volume":"66","author":"Czech","year":"1980","journal-title":"J. Clin. Invest."},{"article-title":"Evaluation of selected endocrine complications in patients treated with auto- and allo-haematopoietic stem cell transplantation] - PubMed n.d","key":"2023072615005225100_B213"},{"key":"2023072615005225100_B214","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1113\/jphysiol.1965.sp007665","article-title":"Influence of the thyroid gland on the accumulation of sugars in rat intestinal mucosa during absorption","volume":"179","author":"Bronk","year":"1965","journal-title":"J. Physiol."},{"key":"2023072615005225100_B215","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.etap.2004.03.001","article-title":"The effects of low-esterified pectin on lead-induced thyroid injury in rats","volume":"17","author":"Khotimchenko","year":"2004","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"2023072615005225100_B216","doi-asserted-by":"publisher","DOI":"10.1038\/cddiscovery.2015.47","article-title":"Inhibition of malignant thyroid carcinoma cell proliferation by Ras and galectin-3 inhibitors","volume":"1","author":"Menachem","year":"2015","journal-title":"Cell Death Discov."},{"key":"2023072615005225100_B217","doi-asserted-by":"publisher","first-page":"101475","DOI":"10.18632\/oncotarget.21135","article-title":"Galectin-3 induced by hypoxia promotes cell migration in thyroid cancer cells","volume":"8","author":"Zheng","year":"2017","journal-title":"Oncotarget"},{"key":"2023072615005225100_B218","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/3578402","article-title":"In Vitro and In Vivo Anti-Salmonella Evaluation of Pectin Extracts and Hydrolysates from \u201cCas Mango\u201d (Spondias dulcis)","volume":"2019","author":"Zofou","year":"2019","journal-title":"Evid Based Complement Alternat Med."},{"key":"2023072615005225100_B219","first-page":"4","article-title":"Free serotonin level in the blood of patients with borderline and essential hypertension","volume":"33","author":"Wocial","year":"1990","journal-title":"J. Chromatogr. B Biomed. Appl."},{"key":"2023072615005225100_B220","doi-asserted-by":"publisher","first-page":"9703","DOI":"10.1021\/acs.analchem.7b01257","article-title":"In Vivo Ambient Serotonin Measurements at Carbon-Fiber Microelectrodes","volume":"89","author":"Abdalla","year":"2017","journal-title":"Anal. Chem."},{"key":"2023072615005225100_B221","first-page":"439","article-title":"The effect of intrahypothalamic serotonin reinforcement on directional preference in rats","volume":"41","author":"Lesiecka","year":"1981","journal-title":"Acta Neurobiol. Exp. (Wars)"},{"key":"2023072615005225100_B222","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.biochi.2014.06.020","article-title":"Serotonin activates cell survival and apoptotic death responses in cultured epithelial thyroid cells","volume":"105","author":"Cerulo","year":"2014","journal-title":"Biochimie"},{"key":"2023072615005225100_B223","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1002\/ar.21353","article-title":"Fate map of serotonin transporter-expressing cells in developing mouse thyroid","volume":"294","author":"Spina","year":"2011","journal-title":"Anat Rec. (Hoboken)"},{"key":"2023072615005225100_B224","first-page":"399","article-title":"Tryptophan degradation and antioxidant status in patients with thyroid disorders","volume":"21","author":"\u00dcn\u00fcvar","year":"2018","journal-title":"Arch. Iran Med."},{"key":"2023072615005225100_B225","doi-asserted-by":"publisher","first-page":"E809","DOI":"10.1152\/ajpendo.1997.272.5.E809","article-title":"Interactions between thyroid hormone and tryptophan transport in rat liver are modulated by thyroid status","volume":"272","author":"Kemp","year":"1997","journal-title":"Am. J. Physiol."},{"key":"2023072615005225100_B226","doi-asserted-by":"publisher","first-page":"2822","DOI":"10.1210\/jc.2013-1273","article-title":"Plasmacytoid dendritic cells in patients with autoimmune thyroid disease","volume":"98","author":"Leskela","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"author":"Ritchie","article-title":"Tryptophan and iodothyronine transport interactions in HepG2 human hepatoma cells n.d","key":"2023072615005225100_B227"},{"key":"2023072615005225100_B228","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1002\/bdd.605","article-title":"Quercetin pharmacokinetics in humans","volume":"29","author":"Moon","year":"2008","journal-title":"Biopharm. Drug Dispos."},{"key":"2023072615005225100_B229","doi-asserted-by":"publisher","first-page":"e13002","DOI":"10.1111\/jfbc.13002","article-title":"Relative protective activities of quercetin, quercetin-3-glucoside, and rutin in alcohol-induced liver injury","volume":"43","author":"Lee","year":"2019","journal-title":"J. Food Biochem."},{"key":"2023072615005225100_B230","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1007\/s13346-019-00674-7","article-title":"Characterization of a liposomal copper(II)-quercetin formulation suitable for parenteral use","volume":"10","author":"Chen","year":"2020","journal-title":"Drug Deliv. Transl. Res."},{"key":"2023072615005225100_B231","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1177\/1934578X1200700413","article-title":"Chemical constituents of the aerial parts of Scutellaria lateriflora and their \u03b1-glucosidase inhibitory activities","volume":"7","author":"Kuroda","year":"2012","journal-title":"Nat. Prod. Commun."},{"key":"2023072615005225100_B232","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s12672-020-00382-6","article-title":"Baicalein Is a Phytohormone that Signals Through the Progesterone and Glucocorticoid Receptors","volume":"11","author":"Austin","year":"2020","journal-title":"Horm. Cancer"},{"key":"2023072615005225100_B233","doi-asserted-by":"publisher","first-page":"3961","DOI":"10.2147\/DDDT.S181939","article-title":"Baicalein induces apoptosis and autophagy of breast cancer cells via inhibiting PI3K\/AKT pathway in vivo and vitro","volume":"12","author":"Yan","year":"2018","journal-title":"Drug Des. Devel. Ther."},{"key":"2023072615005225100_B234","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1016\/S0278-6915(02)00064-9","article-title":"Inhibition of thyroid type 1 deiodinase activity by flavonoids","volume":"40","author":"Ferreira","year":"2002","journal-title":"Food Chem. Toxicol."},{"key":"2023072615005225100_B235","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1080\/19390211.2016.1204404","article-title":"Effect of Sesamin Supplementation on Glycemic Status, Inflammatory Markers, and Adiponectin Levels in Patients with Type 2 Diabetes Mellitus","volume":"14","author":"Mohammad Shahi","year":"2017","journal-title":"J. Diet. Suppl."},{"key":"2023072615005225100_B236","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1097\/01.md.0000123095.65294.34","article-title":"Complex drug-drug-disease interactions between amiodarone, warfarin, and the thyroid gland","volume":"83","author":"Kurnik","year":"2004","journal-title":"Medicine (Baltimore)."},{"key":"2023072615005225100_B237","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1097\/MBC.0b013e3282f0981f","article-title":"Effect of methimazole on warfarin anticoagulation in a case of Graves' disease","volume":"19","author":"Akin","year":"2008","journal-title":"Blood Coagul. Fibrinolysis"},{"key":"2023072615005225100_B238","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1001\/jama.1975.03240230039019","article-title":"Warfarin-Induced Hypoprothrombinemia: Potentiation by Hyperthyroidism","volume":"231","author":"Self","year":"1975","journal-title":"JAMA"},{"key":"2023072615005225100_B239","doi-asserted-by":"publisher","first-page":"9887","DOI":"10.1002\/jcb.28271","article-title":"Delphinidin inhibits epidermal growth factor-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma cells","volume":"120","author":"Lim","year":"2019","journal-title":"J. Cell. Biochem."},{"key":"2023072615005225100_B240","first-page":"5954","article-title":"RhoBTB2 (DBC2) functions as a multifunctional tumor suppressor in thyroid cancer cells via mitochondrial apoptotic pathway","volume":"8","author":"Wang","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"2023072615005225100_B241","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.jep.2015.01.039","article-title":"Effect of piperine on inhibition of FFA induced TLR4 mediated inflammation and amelioration of acetic acid induced ulcerative colitis in mice","volume":"164","author":"Gupta","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"2023072615005225100_B242","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1055\/s-2003-42652","article-title":"Piperine lowers the serum concentrations of thyroid hormones, glucose and hepatic 5\u2019D activity in adult male mice","volume":"35","author":"Panda","year":"2003","journal-title":"Horm. Metab. Res."},{"key":"2023072615005225100_B243","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1515\/JBCPP.2006.17.2.71","article-title":"Piperine, an active principle from Piper nigrum, modulates hormonal and apo lipoprotein profiles in hyperlipidemic rats","volume":"17","author":"Vijayakumar","year":"2006","journal-title":"J. Basic Clin. Physiol. Pharmacol."},{"key":"2023072615005225100_B244","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1211\/jpp.59.11.0012","article-title":"Apigenin (4\u2019,5,7-trihydroxyflavone) regulates hyperglycaemia, thyroid dysfunction and lipid peroxidation in alloxan-induced diabetic mice","volume":"59","author":"Panda","year":"2007","journal-title":"J. Pharm. Pharmacol."},{"key":"2023072615005225100_B245","doi-asserted-by":"publisher","first-page":"3464","DOI":"10.1039\/C5FO00671F","article-title":"Apigenin induces autophagic cell death in human papillary thyroid carcinoma BCPAP cells","volume":"6","author":"Zhang","year":"2015","journal-title":"Food Funct."},{"key":"2023072615005225100_B246","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.21873\/anticanres.11502","article-title":"Myricetin Induces Apoptosis of Human Anaplastic Thyroid Cancer Cells via Mitochondria Dysfunction","volume":"37","author":"Jo","year":"2017","journal-title":"Anticancer Res."},{"key":"2023072615005225100_B247","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.cbi.2019.03.031","article-title":"Effects of curcumin and its adjuvant on TPC1 thyroid cell line","volume":"305","author":"Esposito","year":"2019","journal-title":"Chem. Biol. Interact."},{"key":"2023072615005225100_B248","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/s12906-018-2125-9","article-title":"Effects of different extracts of curcumin on TPC1 papillary thyroid cancer cell line","volume":"18","author":"Perna","year":"2018","journal-title":"BMC Complement. Altern. Med."},{"key":"2023072615005225100_B249","doi-asserted-by":"publisher","first-page":"102537","DOI":"10.1016\/j.autrev.2020.102537","article-title":"The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease","volume":"19","author":"McGonagle","year":"2020","journal-title":"Autoimmun. Rev."},{"key":"2023072615005225100_B250","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1038\/nrd1797","article-title":"The vagus nerve and the nicotinic anti-inflammatory pathway","volume":"4","author":"Ulloa","year":"2005","journal-title":"Nat. Rev. Drug Discov."},{"key":"2023072615005225100_B251","first-page":"68","article-title":"Cholinergic anti-inflammatory pathway and its role in treatment of sepsis","volume":"45","author":"Zi","year":"2020","journal-title":"Zhong Nan Da Xue Xue Bao Yi Xue Ban"},{"key":"2023072615005225100_B252","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1016\/j.toxrep.2020.04.012","article-title":"Editorial: Nicotine and SARS-CoV-2: COVID-19 may be a disease of the nicotinic cholinergic system","volume":"7","author":"Farsalinos","year":"2020","journal-title":"Toxicol. Rep."},{"key":"2023072615005225100_B253","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1038\/s41591-021-01283-z","article-title":"Post-acute COVID-19 syndrome","volume":"27","author":"Nalbandian","year":"2021","journal-title":"Nat. Med."},{"key":"2023072615005225100_B254","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1111\/obr.12320","article-title":"Interaction of obesity and infections","volume":"16","author":"Dhurandhar","year":"2015","journal-title":"Obes. Rev."},{"key":"2023072615005225100_B255","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1038\/ijo.2012.62","article-title":"Obesity and the risk and outcome of infection","volume":"37","author":"Huttunen","year":"2013","journal-title":"Int J Obes (Lond)"},{"key":"2023072615005225100_B256","doi-asserted-by":"publisher","first-page":"pp.s64","DOI":"10.1210\/jc.2008-1613","article-title":"Adipocytokines and the metabolic complications of obesity","volume":"93","author":"Rasouli","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2023072615005225100_B257","doi-asserted-by":"publisher","first-page":"76","DOI":"10.4239\/wjd.v1.i3.76","article-title":"Metabolic effects of obesity: A review","volume":"1","author":"Singla","year":"2010","journal-title":"World J. Diab."},{"key":"2023072615005225100_B258","doi-asserted-by":"publisher","first-page":"1068.e3","DOI":"10.1016\/j.cmet.2020.04.021","article-title":"Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes","volume":"31","author":"Zhu","year":"2020","journal-title":"Cell Metab."},{"key":"2023072615005225100_B259","doi-asserted-by":"publisher","first-page":"2579","DOI":"10.1001\/jama.288.20.2579","article-title":"Molecular understanding of hyperglycemia's adverse effects for diabetic complications","volume":"288","author":"Sheetz","year":"2002","journal-title":"JAMA"},{"key":"2023072615005225100_B260","doi-asserted-by":"publisher","first-page":"922.e4","DOI":"10.1016\/j.cmet.2018.08.003","article-title":"Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection","volume":"28","author":"Tsai","year":"2018","journal-title":"Cell Metab."},{"key":"2023072615005225100_B261","doi-asserted-by":"publisher","first-page":"136","DOI":"10.4049\/jimmunol.1301158","article-title":"Leptin metabolically licenses T cells for activation to link nutrition and immunity","volume":"192","author":"Saucillo","year":"2014","journal-title":"J. Immunol."},{"key":"2023072615005225100_B262","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1146\/annurev-immunol-032713-120236","article-title":"Metabolic regulation of immune responses","volume":"32","author":"Ganeshan","year":"2014","journal-title":"Annu. Rev. Immunol."},{"key":"2023072615005225100_B263","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1016\/j.biochi.2009.01.008","article-title":"Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale","volume":"91","author":"Calder","year":"2009","journal-title":"Biochimie"},{"key":"2023072615005225100_B264","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.plefa.2006.05.012","article-title":"Polyunsaturated fatty acids and inflammation","volume":"75","author":"Calder","year":"2006","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"2023072615005225100_B265","doi-asserted-by":"publisher","first-page":"pp.179S","DOI":"10.1093\/ajcn\/71.1.179S","article-title":"Polyunsaturated fatty acids in the food chain in the United States","volume":"71","author":"Kris-Etherton","year":"2000","journal-title":"Am. J. Clin. Nutr."},{"key":"2023072615005225100_B266","doi-asserted-by":"publisher","first-page":"p.1900924","DOI":"10.1002\/mnfr.201900924","article-title":"Hormonal Dysregulation and Unbalanced Specialized Pro-Resolving Mediator Biosynthesis Contribute toward Impaired B Cell Outcomes in Obesity","volume":"65","author":"Crouch","year":"2021","journal-title":"Mol. Nutr. Food Res."},{"key":"2023072615005225100_B267","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.virol.2008.08.026","article-title":"Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2","volume":"381","author":"Glende","year":"2008","journal-title":"Virology"},{"key":"2023072615005225100_B268","doi-asserted-by":"publisher","first-page":"154244","DOI":"10.1016\/j.metabol.2020.154244","article-title":"Letter to the Editor: Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease","volume":"108","author":"Zheng","year":"2020","journal-title":"Metabolism"},{"key":"2023072615005225100_B269","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1038\/s41574-020-0364-6","article-title":"Obesity and impaired metabolic health in patients with COVID-19","volume":"16","author":"Stefan","year":"2020","journal-title":"Nat. Rev. Endocrinol."},{"key":"2023072615005225100_B270","doi-asserted-by":"publisher","DOI":"10.4081\/monaldi.2022.2307","article-title":"Predictors of post COVID complications in patients admitted with moderate to severe COVID symptoms: A single center, prospective, observational study","volume":"93","author":"Guliani","year":"2022","journal-title":"Monaldi Arch. Chest Dis."},{"key":"2023072615005225100_B271","doi-asserted-by":"crossref","first-page":"34","DOI":"10.3329\/birdem.v13i1.63895","article-title":"Post-COVID fatigue: a new era of complication by altered thyroid function","volume":"13","author":"Alam","year":"2023","journal-title":"BIRDEM Med. J."},{"key":"2023072615005225100_B272","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.antiviral.2005.02.007","article-title":"Identification of natural compounds with antiviral activities against SARS-associated coronavirus","volume":"67","author":"Li","year":"2005","journal-title":"Antiviral Res."},{"key":"2023072615005225100_B273","doi-asserted-by":"crossref","first-page":"100407","DOI":"10.1016\/j.imr.2020.100407","article-title":"Herbal medicine and pattern identification for treating COVID-19: a rapid review of guidelines","volume":"9","author":"Ang","year":"2020","journal-title":"Integr. Med. Res."},{"key":"2023072615005225100_B274","first-page":"1","article-title":"Plant-based bioactive molecules for targeting of endoribonuclease using steered molecular dynamic simulation approach: a highly conserved therapeutic target against variants of SARS-CoV-2","author":"Parihar","year":"2022"},{"key":"2023072615005225100_B275","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/s41586-022-05514-2","article-title":"Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir","volume":"613","author":"Iketani","year":"2023","journal-title":"Nature"},{"key":"2023072615005225100_B276","article-title":"Naturally occurring mutations of SARS-CoV-2 main protease confer drug resistance to nirmatrelvir","author":"Hu","year":"2022","journal-title":"BioRxiv"},{"key":"2023072615005225100_B277","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1743-422X-6-5","article-title":"Viruses and thyroiditis: an update","volume":"6","author":"Desailloud","year":"2009","journal-title":"Virol J."},{"key":"2023072615005225100_B278","doi-asserted-by":"publisher","first-page":"100578","DOI":"10.1016\/j.imu.2021.100578","article-title":"Immunoinformatics and molecular modeling approach to design universal multi-epitope vaccine for SARS-CoV-2","volume":"24","author":"Khan","year":"2021","journal-title":"Inform Med. Unlocked"},{"key":"2023072615005225100_B279","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"A Novel Coronavirus from Patients with Pneumonia in China, 2019","volume":"382","author":"Zhu","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"2023072615005225100_B280","doi-asserted-by":"publisher","first-page":"1016.e19","DOI":"10.1016\/j.cell.2020.04.035","article-title":"SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues","volume":"181","author":"Ziegler","year":"2020","journal-title":"Cell"}],"container-title":["Bioscience Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/bioscirep\/article-pdf\/doi\/10.1042\/BSR20230293\/948500\/bsr-2023-0293c.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/bioscirep\/article-pdf\/doi\/10.1042\/BSR20230293\/948500\/bsr-2023-0293c.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T15:49:11Z","timestamp":1690386551000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/bioscirep\/article\/43\/7\/BSR20230293\/233071\/COVID-19-associated-thyroid-dysfunction-and-other"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":280,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7,26]]}},"URL":"https:\/\/doi.org\/10.1042\/bsr20230293","relation":{},"ISSN":["0144-8463","1573-4935"],"issn-type":[{"type":"print","value":"0144-8463"},{"type":"electronic","value":"1573-4935"}],"subject":[],"published-other":{"date-parts":[[2023,7]]},"published":{"date-parts":[[2023,7]]},"article-number":"BSR20230293"}}