{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T13:59:41Z","timestamp":1779890381055,"version":"3.53.1"},"reference-count":11,"publisher":"Portland Press Ltd.","issue":"4","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2004,8,1]]},"abstract":"<jats:p>The need for an effective TB (tuberculosis) vaccine remains acute, with tuberculosis still one of the major killers worldwide and 3\u00a0million new infections annually. We report here on the immune responses elicited by HspCs (heat-shock protein\u2013peptide complexes) isolated from BCG (Bacille Calmette\u2013Gu\u00e9rin) vaccine. These HspCs elicit both the appropriate cellular and protective immune responses required to merit their further development as TB vaccine candidates.<\/jats:p>","DOI":"10.1042\/bst0320626","type":"journal-article","created":{"date-parts":[[2004,8,2]],"date-time":"2004-08-02T12:00:45Z","timestamp":1091448045000},"page":"626-628","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["BCG (Bacille Calmette\u2013Gu\u00e9rin) HspCs (heat-shock protein\u2013peptide complexes) induce T-helper 1 responses and protect against live challenge in a murine aerosol challenge model of pulmonary tuberculosis"],"prefix":"10.1042","volume":"32","author":[{"given":"C.A.L.S.","family":"Colaco","sequence":"first","affiliation":[{"name":"ImmunoBiology Limited, Babraham BioIncubator, Babraham, Cambridge CB2 4AT, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.R.","family":"Bailey","sequence":"additional","affiliation":[{"name":"ImmunoBiology Limited, Babraham BioIncubator, Babraham, Cambridge CB2 4AT, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Keeble","sequence":"additional","affiliation":[{"name":"National Institute for Biological Standards and Control, South Mimms, Herts. 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