{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:57:08Z","timestamp":1787500628056,"version":"build-2736575974"},"reference-count":43,"publisher":"Portland Press Ltd.","issue":"4","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,8,1]]},"abstract":"<jats:p>Air pollution has been estimated to be responsible for several millions of deaths worldwide per year, the majority of which have been attributed to cardiovascular causes. The particulate matter in air pollution has been shown impair vascular function, increase blood pressure, promote thrombosis and impair fibrinolysis, accelerate the development of atherosclerosis, increase the extent of myocardial ischaemia, and increase susceptibility to myocardial infarction. The pathways underlying these effects are complex and poorly understood; however, particulate-induced oxidative stress repeatedly emerges as a potential mechanism in all of these detrimental cardiovascular actions. The present mini-review will use diesel exhaust as an example of a pollutant rich in combustion-derived nanoparticles, to describe the potential by which oxidative stress could drive the cardiovascular effects of air pollution.<\/jats:p>","DOI":"10.1042\/bst20140090","type":"journal-article","created":{"date-parts":[[2014,8,11]],"date-time":"2014-08-11T07:55:37Z","timestamp":1407743737000},"page":"1006-1011","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":111,"title":["The role of oxidative stress in the cardiovascular actions of particulate air pollution"],"prefix":"10.1042","volume":"42","author":[{"given":"Mark\u00a0R.","family":"Miller","sequence":"first","affiliation":[{"name":"University\/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","published-online":{"date-parts":[[2014,8,11]]},"reference":[{"key":"2021111818235315900_B1","doi-asserted-by":"publisher","first-page":"2331","DOI":"10.1161\/CIR.0b013e3181dbece1","article-title":"Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association","volume":"121","author":"Brook","year":"2010","journal-title":"Circulation"},{"key":"2021111818235315900_B2","doi-asserted-by":"publisher","first-page":"2224","DOI":"10.1016\/S0140-6736(12)61766-8","article-title":"A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990\u20132010: a systematic analysis for the Global Burden of Disease Study 2010","volume":"380","author":"Lim","year":"2012","journal-title":"Lancet"},{"key":"2021111818235315900_B3","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1080\/10473289.2007.10465322","article-title":"Source apportionment of daily fine particulate matter at Jefferson Street, Atlanta, GA, during summer and winter","volume":"57","author":"Zheng","year":"2007","journal-title":"J. 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