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I suggest that this is part of the basis for selective vulnerability in neurodegenerative disease.<\/jats:p>","DOI":"10.1042\/bst20150287","type":"journal-article","created":{"date-parts":[[2016,4,11]],"date-time":"2016-04-11T09:57:10Z","timestamp":1460368630000},"page":"659-661","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Catastrophic cliffs: a partial suggestion for selective vulnerability in neurodegenerative diseases"],"prefix":"10.1042","volume":"44","author":[{"given":"John","family":"Hardy","sequence":"first","affiliation":[{"name":"Reta Lila Weston Research Laboratories, UCL Institute of Neurology, Queen Square, London WC1N3BG, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","published-online":{"date-parts":[[2016,4,11]]},"reference":[{"key":"2021111818123628900_B1","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1001\/jamaneurol.2014.756","article-title":"Insights from cerebellar transcriptomic analysis into the pathogenesis of ataxia","volume":"71","author":"Bettencourt","year":"2014","journal-title":"JAMA Neurol."},{"key":"2021111818123628900_B2","doi-asserted-by":"publisher","first-page":"1749","DOI":"10.1126\/science.7792600","article-title":"A single ataxia telangiectasia gene with a product similar to PI-3 kinase","volume":"268","author":"Savitsky","year":"1995","journal-title":"Science"},{"key":"2021111818123628900_B3","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.ajhg.2015.01.005","article-title":"Mutations in PNKP cause recessive ataxia with oculomotor apraxia type\u00a04","volume":"96","author":"Bras","year":"2015","journal-title":"Am. 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