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Extracellular vesicles (EVs) including exosomes and microvesicles are implicated in cell\u2013cell communication, immune response, tissue repair, epigenetic regulation, and in various diseases including cancer. It has been reported that these EVs regulate cancer progression, metastasis, organotropism and chemoresistance. In recent times, the role of EVs in regulating cancer cachexia is beginning to unravel. The aim of this mini article is to review the recent knowledge gained in the field of EVs and cancer cachexia. Specifically, the role of tumour cell-derived EVs in promoting catabolism in distally located skeletal muscles and adipose tissue will be discussed.<\/jats:p>","DOI":"10.1042\/bst20180213","type":"journal-article","created":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T06:41:10Z","timestamp":1537512070000},"page":"1129-1136","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":63,"title":["Emerging role of extracellular vesicles in mediating cancer cachexia"],"prefix":"10.1042","volume":"46","author":[{"given":"Sai V.","family":"Chitti","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamali","family":"Fonseka","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Mathivanan","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","published-online":{"date-parts":[[2018,9,21]]},"reference":[{"key":"2021111818144185800_BST-2018-0213CC1","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon","year":"2011","journal-title":"Lancet Oncol."},{"key":"2021111818144185800_BST-2018-0213CC2","doi-asserted-by":"publisher","first-page":"212265","DOI":"10.7573\/dic.212265","article-title":"One-year prevalence, comorbidities and cost of cachexia-related inpatient admissions in the USA","volume":"3","author":"Arthur","year":"2014","journal-title":"Drugs Context"},{"key":"2021111818144185800_BST-2018-0213CC3","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1038\/nrclinonc.2012.209","article-title":"Understanding the mechanisms and treatment options in cancer cachexia","volume":"10","author":"Fearon","year":"2013","journal-title":"Nat. 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