{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T16:26:41Z","timestamp":1784824001199,"version":"3.55.0"},"reference-count":136,"publisher":"Portland Press Ltd.","issue":"2","license":[{"start":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T00:00:00Z","timestamp":1678924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,4,26]]},"abstract":"<jats:p>Protein N-linked glycosylation is a structurally diverse post-translational modification that stores biological information in a larger order of magnitude than other post-translational modifications such as phosphorylation, ubiquitination and acetylation. This gives N-glycosylated proteins a diverse range of properties and allows glyco-codes (glycan-related information) to be deciphered by glycan-binding proteins (GBPs). The intervillous space of the placenta is richly populated with membrane-bound and secreted glycoproteins. Evidence exists to suggest that altering the structural nature of their N-glycans can impact several trophoblast functions, which include those related to interactions with decidual cells. This review summarizes trophoblast-related activities influenced by N-glycan\u2013GBP recognition, exploring how different subtypes of trophoblasts actively adapt to characteristics of the decidualized endometrium through cell-specific expression of N-glycosylated proteins, and how these cells receive decidua-derived signals via N-glycan\u2013GBP interactions. We highlight work on how changes in N-glycosylation relates to the success of trophoblast infiltration, interactions of immunomodulators, and uterine angiogenesis. We also discuss studies that suggest aberrant N-glycosylation of trophoblasts may contribute to the pathogenesis of pregnancy complications (e.g. pre-eclampsia, early spontaneous miscarriages and hydatidiform mole). We propose that a more in-depth understanding of how N-glycosylation shapes trophoblast phenotype during early pregnancy has the potential to improve our approach to predicting, diagnosing and alleviating poor maternal\/fetal outcomes associated with placental dysfunction.<\/jats:p>","DOI":"10.1042\/bst20221406","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T14:57:31Z","timestamp":1678978651000},"page":"639-653","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology"],"prefix":"10.1042","volume":"51","author":[{"given":"Zhengyuan","family":"Huang","sequence":"first","affiliation":[{"name":"1Division of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London SW10 9NH, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4669-7029","authenticated-orcid":false,"given":"Pei F.","family":"Lai","sequence":"additional","affiliation":[{"name":"1Division of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London SW10 9NH, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7162-0774","authenticated-orcid":false,"given":"Alexander T. H.","family":"Cocker","sequence":"additional","affiliation":[{"name":"2Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart M.","family":"Haslam","sequence":"additional","affiliation":[{"name":"3Department of Life Sciences, Imperial College London, London SW7 2AZ, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Dell","sequence":"additional","affiliation":[{"name":"3Department of Life Sciences, Imperial College London, London SW7 2AZ, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugh J. M.","family":"Brady","sequence":"additional","affiliation":[{"name":"3Department of Life Sciences, Imperial College London, London SW7 2AZ, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Johnson","sequence":"additional","affiliation":[{"name":"1Division of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London SW10 9NH, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","published-online":{"date-parts":[[2023,3,16]]},"reference":[{"key":"2023042614592984600_BST-2022-1406C1","doi-asserted-by":"publisher","first-page":"dev163428","DOI":"10.1242\/dev.163428","article-title":"Development of the human placenta","volume":"146","year":"2019","journal-title":"Development"},{"key":"2023042614592984600_BST-2022-1406C2","doi-asserted-by":"publisher","first-page":"3479","DOI":"10.1007\/s00018-019-03104-6","article-title":"Human placenta and trophoblast development: key molecular mechanisms and model systems","volume":"76","year":"2019","journal-title":"Cell. Mol. Life Sci."},{"key":"2023042614592984600_BST-2022-1406C3","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.placenta.2022.06.014","article-title":"Role of osteopontin (OPN) in uterine spiral artery remodeling","volume":"126","year":"2022","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C4","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.mam.2016.06.002","article-title":"The human fetoembryonic defense system hypothesis: twenty years on","volume":"51","year":"2016","journal-title":"Mol. Aspects Med."},{"key":"2023042614592984600_BST-2022-1406C5","doi-asserted-by":"publisher","first-page":"69","DOI":"10.3390\/ijms23010069","article-title":"Galectins in early pregnancy and pregnancy-associated pathologies","volume":"23","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"2023042614592984600_BST-2022-1406C6","doi-asserted-by":"publisher","first-page":"101630","DOI":"10.1016\/j.tice.2021.101630","article-title":"The expression and role of glycans at the feto-maternal interface in humans","volume":"73","year":"2021","journal-title":"Tissue Cell"},{"key":"2023042614592984600_BST-2022-1406C7","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.3389\/fimmu.2019.01166","article-title":"Pregnancy galectinology: insights into a complex network of glycan binding proteins","volume":"10","year":"2019","journal-title":"Front. Immunol."},{"key":"2023042614592984600_BST-2022-1406C8","volume-title":"N-Glycans","year":"2022"},{"key":"2023042614592984600_BST-2022-1406C9","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1093\/jb\/mvx061","article-title":"Integrin \u03b21 is bound to galectin-1 in human trophoblast","volume":"163","year":"2018","journal-title":"J. Biochem."},{"key":"2023042614592984600_BST-2022-1406C10","doi-asserted-by":"publisher","first-page":"e0228507","DOI":"10.1371\/journal.pone.0228507","article-title":"Insights into the hyperglycosylation of human chorionic gonadotropin revealed by glycomics analysis","volume":"15","year":"2020","journal-title":"PLoS One"},{"key":"2023042614592984600_BST-2022-1406C11","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1007\/s00281-012-0309-9","article-title":"Roles for major histocompatibility complex glycosylation in immune function","volume":"34","year":"2012","journal-title":"Semin. Immunopathol."},{"key":"2023042614592984600_BST-2022-1406C12","doi-asserted-by":"publisher","first-page":"R11","DOI":"10.1530\/rep-21-0390","article-title":"Pregnancy-specific glycoproteins: evolution, expression, functions and disease associations","volume":"163","year":"2022","journal-title":"Reproduction"},{"key":"2023042614592984600_BST-2022-1406C13","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.cell.2019.05.044","article-title":"Fc glycan-mediated regulation of placental antibody transfer","volume":"178","year":"2019","journal-title":"Cell"},{"key":"2023042614592984600_BST-2022-1406C14","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1093\/molehr\/gat064","article-title":"The role of glycans in immune evasion: the human fetoembryonic defence system hypothesis revisited","volume":"20","year":"2014","journal-title":"Mol. Hum. Reprod."},{"key":"2023042614592984600_BST-2022-1406C15","doi-asserted-by":"publisher","first-page":"103212","DOI":"10.1016\/j.jri.2020.103212","article-title":"Glycan expression in chorionic villi from histocultures of women with early-onset preeclampsia: immunomodulatory effects on peripheral natural killer cells","volume":"142","year":"2020","journal-title":"J. Reprod. Immunol."},{"key":"2023042614592984600_BST-2022-1406C16","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.3389\/fimmu.2020.01316","article-title":"Altered glycosylation contributes to placental dysfunction upon early disruption of the NK cell-DC dynamics","volume":"11","year":"2020","journal-title":"Front. Immunol."},{"key":"2023042614592984600_BST-2022-1406C17","doi-asserted-by":"publisher","first-page":"1574","DOI":"10.1016\/j.bbagen.2015.10.016","article-title":"Mechanisms of disease: the human N-glycome","volume":"1860","year":"2016","journal-title":"Biochim. Biophys. Acta"},{"key":"2023042614592984600_BST-2022-1406C18","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1039\/b907931a","article-title":"The repertoire of glycan determinants in the human glycome","volume":"5","year":"2009","journal-title":"Mol. Biosyst."},{"key":"2023042614592984600_BST-2022-1406C19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.mad.2014.01.010","article-title":"The N-glycan profile of placental membrane glycoproteins alters during gestation and aging","volume":"138","year":"2014","journal-title":"Mech. Ageing Dev."},{"key":"2023042614592984600_BST-2022-1406C20","doi-asserted-by":"publisher","first-page":"111151","DOI":"10.1016\/j.mad.2019.111151","article-title":"Glycoanalysis of the placental membrane glycoproteins throughout placental development","volume":"183","year":"2019","journal-title":"Mech. Ageing Dev."},{"key":"2023042614592984600_BST-2022-1406C21","doi-asserted-by":"publisher","first-page":"1857","DOI":"10.1074\/mcp.M115.055798","article-title":"Evidence for differential glycosylation of trophoblast cell types","volume":"15","year":"2016","journal-title":"Mol. Cell. Proteomics"},{"key":"2023042614592984600_BST-2022-1406C22","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1016\/j.placenta.2015.08.014","article-title":"N-acetylglucosaminyltransferase V inhibits the invasion of trophoblast cells by attenuating MMP2\/9 activity in early human pregnancy","volume":"36","year":"2015","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C23","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1210\/en.2008-1005","article-title":"N-acetylglucosaminyltransferase V regulates extravillous trophoblast invasion through glycosylation of alpha5beta1 integrin","volume":"150","year":"2009","journal-title":"Endocrinology"},{"key":"2023042614592984600_BST-2022-1406C24","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1177\/1933719118765967","article-title":"Expression of N-acetylglucosaminyltransferase III promotes trophoblast invasion and migration in early human placenta","volume":"26","year":"2019","journal-title":"Reprod. Sci."},{"key":"2023042614592984600_BST-2022-1406C25","doi-asserted-by":"publisher","first-page":"32122","DOI":"10.1074\/jbc.M607274200","article-title":"N-acetylglucosaminyltransferase III antagonizes the effect of N-acetylglucosaminyltransferase V on alpha3beta1 integrin-mediated cell migration","volume":"281","year":"2006","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C26","doi-asserted-by":"publisher","first-page":"5708","DOI":"10.1074\/jbc.M115.712836","article-title":"Expression of N-acetylglucosaminyltransferase III suppresses \u03b12,3-sialylation, and Its distinctive functions in cell migration are attributed to \u03b12,6-sialylation levels","volume":"291","year":"2016","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C27","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.placenta.2018.11.005","article-title":"FUT8 drives the proliferation and invasion of trophoblastic cells via IGF-1\/IGF-1R signaling pathway","volume":"75","year":"2019","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C28","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/j.placenta.2015.01.008","article-title":". beta-1,4-galactosyltransferase III suppresses extravillous trophoblast invasion through modifying beta1-integrin glycosylation","volume":"36","year":"2015","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C29","doi-asserted-by":"publisher","first-page":"440","DOI":"10.3892\/or.2017.5661","article-title":"N-acetylglucosaminyltransferase IVa promotes invasion of choriocarcinoma","volume":"38","year":"2017","journal-title":"Oncol. Rep."},{"key":"2023042614592984600_BST-2022-1406C30","doi-asserted-by":"publisher","first-page":"e201900515","DOI":"10.26508\/lsa.201900515","article-title":"Laminin is the ECM niche for trophoblast stem cells","volume":"3","year":"2020","journal-title":"Life Sci."},{"key":"2023042614592984600_BST-2022-1406C31","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1172\/JCI115565","article-title":"Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo","volume":"89","year":"1992","journal-title":"J. Clin. Investig."},{"key":"2023042614592984600_BST-2022-1406C32","doi-asserted-by":"publisher","first-page":"1969","DOI":"10.1038\/bjc.2012.496","article-title":"High expression of N-acetylglucosaminyltransferase IVa promotes invasion of choriocarcinoma","volume":"107","year":"2012","journal-title":"Br. J. Cancer"},{"key":"2023042614592984600_BST-2022-1406C33","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1093\/glycob\/4.5.567","article-title":"Glycosylation of human trophoblast integrins is stage and cell-type specific","volume":"4","year":"1994","journal-title":"Glycobiology"},{"key":"2023042614592984600_BST-2022-1406C34","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1210\/en.2007-1282","article-title":"Human chorionic gonadotropin stimulates trophoblast invasion through extracellularly regulated kinase and AKT signaling","volume":"149","year":"2008","journal-title":"Endocrinology"},{"key":"2023042614592984600_BST-2022-1406C35","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.mce.2013.05.009","article-title":"Human chorionic gonadotropin and its free beta-subunit stimulate trophoblast invasion independent of LH\/hCG receptor","volume":"375","year":"2013","journal-title":"Mol. Cell. Endocrinol."},{"key":"2023042614592984600_BST-2022-1406C36","doi-asserted-by":"publisher","first-page":"2215","DOI":"10.1093\/humrep\/det136","article-title":"Human chorionic gonadotropin (hCG) modulation of TIMP1 secretion by human endometrial stromal cells facilitates extravillous trophoblast invasion in vitro","volume":"28","year":"2013","journal-title":"Hum. Reprod."},{"key":"2023042614592984600_BST-2022-1406C37","doi-asserted-by":"publisher","first-page":"e0125589","DOI":"10.1371\/journal.pone.0125589","article-title":"HCG-activated human peripheral blood mononuclear cells (PBMC) promote trophoblast cell invasion","volume":"10","year":"2015","journal-title":"PLoS One"},{"key":"2023042614592984600_BST-2022-1406C38","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1373\/clinchem.2010.159939","article-title":"Elimination of complement interference in immunoassay of hyperglycosylated human chorionic gonadotropin","volume":"57","year":"2011","journal-title":"Clin. Chem."},{"key":"2023042614592984600_BST-2022-1406C39","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/S0303-7207(02)00135-1","article-title":"Trophoblast origin of hCG isoforms: cytotrophoblasts are the primary source of choriocarcinoma-like hCG","volume":"194","year":"2002","journal-title":"Mol. Cell. Endocrinol."},{"key":"2023042614592984600_BST-2022-1406C40","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.3390\/cells10061305","article-title":"Extracellularly released calreticulin induced by endoplasmic reticulum stress impairs syncytialization of cytotrophoblast model BeWo cells","volume":"10","year":"2021","journal-title":"Cells"},{"key":"2023042614592984600_BST-2022-1406C41","doi-asserted-by":"publisher","first-page":"3874","DOI":"10.1210\/en.2016-1966","article-title":"Calreticulin is involved in invasion of human extravillous trophoblasts through functional regulation of integrin beta1","volume":"158","year":"2017","journal-title":"Endocrinology"},{"key":"2023042614592984600_BST-2022-1406C42","doi-asserted-by":"publisher","first-page":"33507","DOI":"10.1038\/srep33507","article-title":"N-glycosylation of integrin alpha5 acts as a switch for EGFR-mediated complex formation of integrin \u03b15\u03b21 to \u03b16\u03b24","volume":"6","year":"2016","journal-title":"Sci. Rep."},{"key":"2023042614592984600_BST-2022-1406C43","doi-asserted-by":"publisher","first-page":"12207","DOI":"10.1074\/jbc.M807920200","article-title":"N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: identification of the minimal N-glycosylation requirement for \u03b15\u03b21","volume":"284","year":"2009","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C44","doi-asserted-by":"publisher","first-page":"33258","DOI":"10.1074\/jbc.M607771200","article-title":"N-glycosylation of the beta-propeller domain of the integrin alpha5 subunit is essential for \u03b15\u03b21 heterodimerization, expression on the cell surface, and its biological function","volume":"281","year":"2006","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C45","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1007\/s12013-012-9350-5","article-title":"Overexpression of calreticulin in pre-eclamptic placentas: effect on apoptosis, cell invasion and severity of pre-eclampsia","volume":"63","year":"2012","journal-title":"Cell Biochem. Biophys."},{"key":"2023042614592984600_BST-2022-1406C46","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1093\/glycob\/cwm065","article-title":"Human-specific expression of Siglec-6 in the placenta","volume":"17","year":"2007","journal-title":"Glycobiology"},{"key":"2023042614592984600_BST-2022-1406C47","doi-asserted-by":"publisher","first-page":"22729","DOI":"10.1074\/jbc.274.32.22729","article-title":"OB-BP1\/Siglec-6 a leptin-and sialic acid-binding protein of the immunoglobulin superfamily","volume":"274","year":"1999","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C48","doi-asserted-by":"publisher","first-page":"24116","DOI":"10.1074\/jbc.270.41.24116","article-title":"Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities","volume":"270","year":"1995","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C49","doi-asserted-by":"publisher","first-page":"37118","DOI":"10.1074\/jbc.M111.233841","article-title":"Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)\/c-Jun signaling pathway","volume":"286","year":"2011","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C50","doi-asserted-by":"publisher","first-page":"9731","DOI":"10.1073\/pnas.0903568106","article-title":"A primate subfamily of galectins expressed at the maternal\u2013fetal interface that promote immune cell death","volume":"106","year":"2009","journal-title":"Proc. Natl Acad. Sci. U.S.A."},{"key":"2023042614592984600_BST-2022-1406C51","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.tibs.2016.11.003","article-title":"Translating the \u2018Sugar Code\u2019 into immune and vascular signaling programs","volume":"42","year":"2017","journal-title":"Trends Biochem. Sci."},{"key":"2023042614592984600_BST-2022-1406C52","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1093\/glycob\/cws104","article-title":"Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss","volume":"22","year":"2012","journal-title":"Glycobiology"},{"key":"2023042614592984600_BST-2022-1406C53","doi-asserted-by":"publisher","first-page":"2136","DOI":"10.1038\/s41598-018-38374-w","article-title":"Human trophoblast requires galectin-3 for cell migration and invasion","volume":"9","year":"2019","journal-title":"Sci. Rep."},{"key":"2023042614592984600_BST-2022-1406C54","doi-asserted-by":"publisher","first-page":"e28514","DOI":"10.1371\/journal.pone.0028514","article-title":"Galectin-1 is part of human trophoblast invasion machinery\u2013a functional study in vitro","volume":"6","year":"2011","journal-title":"PLoS One"},{"key":"2023042614592984600_BST-2022-1406C55","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1007\/s00418-004-0660-6","article-title":"Binding of galectin-1 (gal-1) on trophoblast cells and inhibition of hormone production of trophoblast tumor cells in vitro by gal-1","volume":"121","year":"2004","journal-title":"Histochem. Cell Biol."},{"key":"2023042614592984600_BST-2022-1406C56","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1016\/j.placenta.2010.06.016","article-title":"Stimulation of syncytium formation in vitro in human trophoblast cells by galectin-1","volume":"31","year":"2010","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C57","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1038\/nm1680","article-title":"A pivotal role for galectin-1 in fetomaternal tolerance","volume":"13","year":"2007","journal-title":"Nat. Med."},{"key":"2023042614592984600_BST-2022-1406C58","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1038\/s41419-020-02791-5","article-title":"Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency","volume":"11","year":"2020","journal-title":"Cell Death Dis."},{"key":"2023042614592984600_BST-2022-1406C59","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1093\/molehr\/gas043","article-title":"Galectin-1 influences trophoblast immune evasion and emerges as a predictive factor for the outcome of pregnancy","volume":"19","year":"2013","journal-title":"Mol. Hum. Reprod."},{"key":"2023042614592984600_BST-2022-1406C60","doi-asserted-by":"publisher","first-page":"e13311","DOI":"10.1111\/aji.13311","article-title":"The chimera-type galectin-3 is a positive modulator of trophoblast functions with dysregulated expression in gestational diabetes mellitus","volume":"84","year":"2020","journal-title":"Am. J. Reprod. Immunol."},{"key":"2023042614592984600_BST-2022-1406C61","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.placenta.2014.01.004","article-title":"Galectin-7 acts as an adhesion molecule during implantation and increased expression is associated with miscarriage","volume":"35","year":"2014","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C62","doi-asserted-by":"publisher","first-page":"645658","DOI":"10.3389\/fcell.2021.645658","article-title":"Galectin-14 promotes trophoblast migration and invasion by upregulating the expression of MMP-9 and N-cadherin","volume":"9","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"2023042614592984600_BST-2022-1406C63","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1016\/j.placenta.2011.07.087","article-title":"Galectin-8 is expressed by villous and extravillous trophoblast of the human placenta","volume":"32","year":"2011","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C64","doi-asserted-by":"publisher","first-page":"4518","DOI":"10.1021\/acs.jproteome.1c00466","article-title":"Allotype-specific glycosylation and cellular localization of human leukocyte antigen class I proteins","volume":"20","year":"2021","journal-title":"J. Proteome Res."},{"key":"2023042614592984600_BST-2022-1406C65","doi-asserted-by":"publisher","first-page":"55","DOI":"10.3389\/fchem.2020.00055","article-title":"Biological and technical challenges in unraveling the role of N-glycans in immune receptor regulation","volume":"8","year":"2020","journal-title":"Front. Chem."},{"key":"2023042614592984600_BST-2022-1406C66","doi-asserted-by":"publisher","first-page":"2374","DOI":"10.1080\/21645515.2020.1730658","article-title":"Human T cell glycosylation and implications on immune therapy for cancer","volume":"16","year":"2020","journal-title":"Hum. Vaccines Immunother."},{"key":"2023042614592984600_BST-2022-1406C67","doi-asserted-by":"publisher","first-page":"e12802","DOI":"10.1111\/cpr.12802","article-title":"Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T-cell differentiation along the maternal-placental circulation","volume":"53","year":"2020","journal-title":"Cell Prolif."},{"key":"2023042614592984600_BST-2022-1406C68","doi-asserted-by":"publisher","first-page":"16469","DOI":"10.1074\/jbc.M709175200","article-title":"N-linked glycosylation selectively regulates the generic folding of HLA-Cw1","volume":"283","year":"2008","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C69","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.1016\/s0198-8859(00)00184-1","article-title":"N-linked carbohydrate on human leukocyte antigen-C and recognition by natural killer cell inhibitory receptors","volume":"61","year":"2000","journal-title":"Hum. Immunol."},{"key":"2023042614592984600_BST-2022-1406C70","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1038\/s41586-018-0698-6","article-title":"Single-cell reconstruction of the early maternal\u2013fetal interface in humans","volume":"563","year":"2018","journal-title":"Nature"},{"key":"2023042614592984600_BST-2022-1406C71","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1084\/jem.20041214","article-title":"Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success","volume":"200","year":"2004","journal-title":"J. Exp. Med."},{"key":"2023042614592984600_BST-2022-1406C72","doi-asserted-by":"publisher","first-page":"e12643","DOI":"10.1111\/aji.12643","article-title":"Definitive class I human leukocyte antigen expression in gestational placentation: HLA-F, HLA-E, HLA-C, and HLA-G in extravillous trophoblast invasion on placentation, pregnancy, and parturition","volume":"77","year":"2017","journal-title":"Am. J. Reprod. Immunol."},{"key":"2023042614592984600_BST-2022-1406C73","doi-asserted-by":"publisher","first-page":"5922","DOI":"10.4049\/jimmunol.160.12.5922","article-title":"HLA-G isoforms produced by placental cytotrophoblasts and found in amniotic fluid are due to unusual glycosylation","volume":"160","year":"1998","journal-title":"J. Immunol."},{"key":"2023042614592984600_BST-2022-1406C74","doi-asserted-by":"publisher","first-page":"181","DOI":"10.4132\/jptm.2015.02.25","article-title":"Galectins: double-edged swords in the cross-roads of pregnancy complications and female reproductive tract inflammation and neoplasia","volume":"49","year":"2015","journal-title":"J. Pathol. Transl. Med."},{"key":"2023042614592984600_BST-2022-1406C75","doi-asserted-by":"publisher","first-page":"877","DOI":"10.3389\/fimmu.2017.00877","article-title":"Decoding the human immunoglobulin G-glycan repertoire reveals a spectrum of Fc-receptor- and complement-mediated-effector activities","volume":"8","year":"2017","journal-title":"Front. Immunol."},{"key":"2023042614592984600_BST-2022-1406C76","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1038\/nri2155","article-title":"Fcrn: the neonatal Fc receptor comes of age","volume":"7","year":"2007","journal-title":"Nat. Rev. Immunol."},{"key":"2023042614592984600_BST-2022-1406C77","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.molimm.2017.12.006","article-title":"Conserved Fc\u03b3R- glycan discriminates between fucosylated and afucosylated IgG in humans and mice","volume":"94","year":"2018","journal-title":"Mol. Immunol."},{"key":"2023042614592984600_BST-2022-1406C78","doi-asserted-by":"publisher","first-page":"12669","DOI":"10.1073\/pnas.1108455108","article-title":"Unique carbohydrate-carbohydrate interactions are required for high affinity binding between FcgammaRIII and antibodies lacking core fucose","volume":"108","year":"2011","journal-title":"Proc. Natl Acad. Sci. U.S.A."},{"key":"2023042614592984600_BST-2022-1406C79","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/s10719-012-9381-6","article-title":"Comparison of the Fc glycosylation of fetal and maternal immunoglobulin G","volume":"30","year":"2013","journal-title":"Glycoconj. J."},{"key":"2023042614592984600_BST-2022-1406C80","doi-asserted-by":"publisher","first-page":"12943","DOI":"10.1073\/pnas.2004325117","article-title":"Fcrn, but not Fc\u03b3Rs, drives maternal-fetal transplacental transport of human IgG antibodies","volume":"117","year":"2020","journal-title":"Proc. Natl Acad. Sci. U.S.A."},{"key":"2023042614592984600_BST-2022-1406C81","doi-asserted-by":"publisher","first-page":"2454","DOI":"10.1093\/humrep\/deaa223","article-title":"Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts","volume":"35","year":"2020","journal-title":"Hum. Reprod."},{"key":"2023042614592984600_BST-2022-1406C82","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1038\/cmi.2014.126","article-title":"The Galectin-9\/Tim-3 pathway is involved in the regulation of NK cell function at the maternal\u2013fetal interface in early pregnancy","volume":"13","year":"2016","journal-title":"Cell. Mol. Immunol."},{"key":"2023042614592984600_BST-2022-1406C83","doi-asserted-by":"publisher","first-page":"e0147186","DOI":"10.1371\/journal.pone.0147186","article-title":"Tim-3 is upregulated in NK cells during early pregnancy and inhibits NK cytotoxicity toward trophoblast in galectin-9 dependent pathway","volume":"11","year":"2016","journal-title":"PLoS One"},{"key":"2023042614592984600_BST-2022-1406C84","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1177\/1933719111424445","article-title":"Placental protein 13 and decidual zones of necrosis: an immunologic diversion that may be linked to preeclampsia","volume":"19","year":"2012","journal-title":"Reprod. Sci."},{"key":"2023042614592984600_BST-2022-1406C85","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.placenta.2018.04.013","article-title":"Reduced placental protein 13 (PP13) in placental derived syncytiotrophoblast extracellular vesicles in preeclampsia - a novel tool to study the impaired cargo transmission of the placenta to the maternal organs","volume":"66","year":"2018","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C86","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3389\/fimmu.2020.00145","article-title":"Placental protein 13 (galectin-13) polarizes neutrophils toward an immune regulatory phenotype","volume":"11","year":"2020","journal-title":"Front. Immunol."},{"key":"2023042614592984600_BST-2022-1406C87","doi-asserted-by":"publisher","first-page":"348","DOI":"10.3389\/fimmu.2014.00348","article-title":"Placental protein 13 (PP13) - a placental immunoregulatory galectin protecting pregnancy","volume":"5","year":"2014","journal-title":"Front. Immunol."},{"key":"2023042614592984600_BST-2022-1406C88","doi-asserted-by":"publisher","first-page":"1909","DOI":"10.3390\/biom11121909","article-title":"Expression, regulation, and functions of the galectin-16 gene in human cells and tissues","volume":"11","year":"2021","journal-title":"Biomolecules"},{"key":"2023042614592984600_BST-2022-1406C89","doi-asserted-by":"publisher","first-page":"784473","DOI":"10.3389\/fimmu.2021.784473","article-title":"Medawar's PostEra: galectins emerged as key players during fetal-maternal glycoimmune adaptation","volume":"12","year":"2021","journal-title":"Front. Immunol."},{"key":"2023042614592984600_BST-2022-1406C90","doi-asserted-by":"publisher","first-page":"5541","DOI":"10.1091\/mbc.e08-02-0166","article-title":"Galectin-7 in the control of epidermal homeostasis after injury","volume":"19","year":"2008","journal-title":"Mol. Biol. Cell"},{"key":"2023042614592984600_BST-2022-1406C91","doi-asserted-by":"publisher","first-page":"7577","DOI":"10.1074\/jbc.M110.161810","article-title":"Pregnancy-specific glycoprotein 1 induces endothelial tubulogenesis through interaction with cell surface proteoglycans","volume":"286","year":"2011","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C92","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1095\/biolreprod.109.082412","article-title":"Human pregnancy specific beta-1-glycoprotein 1 (PSG1) has a potential role in placental vascular morphogenesis","volume":"83","year":"2010","journal-title":"Biol. Reprod."},{"key":"2023042614592984600_BST-2022-1406C93","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1530\/rep-20-0169","article-title":"Pro-angiogenic effects of pregnancy-specific glycoproteins in endothelial and extravillous trophoblast cells","volume":"160","year":"2020","journal-title":"Reproduction"},{"key":"2023042614592984600_BST-2022-1406C94","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/1471-2148-5-39","article-title":"Conservation of pregnancy-specific glycoprotein (PSG) N domains following independent expansions of the gene families in rodents and primates","volume":"5","year":"2005","journal-title":"BMC Evol. Biol."},{"key":"2023042614592984600_BST-2022-1406C95","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1093\/glycob\/cwaa034","article-title":"Glycan characterization of pregnancy-specific glycoprotein 1 and its identification as a novel Galectin-1 ligand","volume":"30","year":"2020","journal-title":"Glycobiology"},{"key":"2023042614592984600_BST-2022-1406C96","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.3390\/cells8111369","article-title":"Interaction of pregnancy-specific glycoprotein 1 with integrin \u03915\u03b21 is a modulator of extravillous trophoblast functions","volume":"8","year":"2019","journal-title":"Cells"},{"key":"2023042614592984600_BST-2022-1406C97","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1093\/molehr\/gay044","article-title":"Activation of latent transforming growth factor-\u03b21, a conserved function for pregnancy-specific beta 1-glycoproteins","volume":"24","year":"2018","journal-title":"Mol. Hum. Reprod."},{"key":"2023042614592984600_BST-2022-1406C98","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1038\/mi.2013.53","article-title":"Pregnancy-specific glycoprotein 1 (PSG1) activates TGF-\u03b2 and prevents dextran sodium sulfate (DSS)-induced colitis in mice","volume":"7","year":"2014","journal-title":"Mucosal Immunol."},{"key":"2023042614592984600_BST-2022-1406C99","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/bs.pmbts.2017.04.001","article-title":"Matrix metalloproteinases in normal pregnancy and preeclampsia","volume":"148","year":"2017","journal-title":"Prog. Mol. Biol. Transl. Sci."},{"key":"2023042614592984600_BST-2022-1406C100","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1053\/plac.2002.0867","article-title":"Expression and activity of matrix metalloproteinase 2 and 9 in human trophoblasts","volume":"24","year":"2003","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C101","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1038\/nature10897","article-title":"Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy","volume":"484","year":"2012","journal-title":"Nature"},{"key":"2023042614592984600_BST-2022-1406C102","doi-asserted-by":"publisher","first-page":"27728","DOI":"10.1074\/jbc.M703687200","article-title":"Role of glycosylation in corin zymogen activation","volume":"282","year":"2007","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C103","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.placenta.2003.12.009","article-title":"Placental protein 13 (PP-13): effects on cultured trophoblasts, and its detection in human body fluids in normal and pathological pregnancies","volume":"25","year":"2004","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C104","doi-asserted-by":"publisher","first-page":"3192","DOI":"10.3390\/ijms20133192","article-title":"Galectin 13 (PP13) facilitates remodeling and structural stabilization of maternal vessels during pregnancy","volume":"20","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"2023042614592984600_BST-2022-1406C105","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1159\/000345964","article-title":"Effects of placental protein 13 on the cardiovascular system in gravid and non-gravid rodents","volume":"33","year":"2013","journal-title":"Fetal Diagn. Ther."},{"key":"2023042614592984600_BST-2022-1406C106","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1080\/10641955.2017.1295052","article-title":"Placental protein 13 (PP13)-induced vasodilation of resistance arteries from pregnant and nonpregnant rats occurs via endothelial-signaling pathways","volume":"36","year":"2017","journal-title":"Hypertens Pregnancy"},{"key":"2023042614592984600_BST-2022-1406C107","doi-asserted-by":"publisher","first-page":"3369","DOI":"10.4049\/jimmunol.170.6.3369","article-title":"IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis","volume":"170","year":"2003","journal-title":"J. Immunol."},{"key":"2023042614592984600_BST-2022-1406C108","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.3389\/fimmu.2019.01240","article-title":"Placental galectins are key players in regulating the maternal adaptive immune response","volume":"10","year":"2019","journal-title":"Front. Immunol."},{"key":"2023042614592984600_BST-2022-1406C109","doi-asserted-by":"publisher","first-page":"2064","DOI":"10.1093\/humrep\/dev153","article-title":"Altered beta1,6-GlcNAc and bisecting GlcNAc-branched N-glycan on integrin beta1 are associated with early spontaneous miscarriage in humans","volume":"30","year":"2015","journal-title":"Hum. Reprod."},{"key":"2023042614592984600_BST-2022-1406C110","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1016\/j.acthis.2010.12.001","article-title":"Distribution of sugar residues in human placentas from pregnancies complicated by hypertensive disorders","volume":"113","year":"2011","journal-title":"Acta Histochem."},{"key":"2023042614592984600_BST-2022-1406C111","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.jri.2016.08.008","article-title":"Update of syncytiotrophoblast derived extracellular vesicles in normal pregnancy and preeclampsia","volume":"119","year":"2017","journal-title":"J. Reprod. Immunol."},{"key":"2023042614592984600_BST-2022-1406C112","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.placenta.2016.05.002","article-title":"Differences of glycocalyx composition in the structural elements of placenta in preeclampsia","volume":"43","year":"2016","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C113","doi-asserted-by":"publisher","first-page":"11451","DOI":"10.1073\/pnas.1303707110","article-title":"Interfering with Gal-1-mediated angiogenesis contributes to the pathogenesis of preeclampsia","volume":"110","year":"2013","journal-title":"Proc. Natl Acad. Sci. U.S.A."},{"key":"2023042614592984600_BST-2022-1406C114","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1177\/1933719116655602","article-title":"The role of MGAT5 in human umbilical vein endothelial cells","volume":"24","year":"2017","journal-title":"Reprod. Sci."},{"key":"2023042614592984600_BST-2022-1406C115","doi-asserted-by":"publisher","first-page":"2369","DOI":"10.1080\/14767058.2018.1438392","article-title":"Downregulated N-acetylglucosaminyltransferase III is involved in attenuating trophoblast migration and invasion under hypoxia-reoxygenation condition","volume":"32","year":"2019","journal-title":"J. Matern.-Fetal Neonatal Med."},{"key":"2023042614592984600_BST-2022-1406C116","doi-asserted-by":"publisher","first-page":"14126","DOI":"10.1016\/S0021-9258(17)43832-4","article-title":"Structures of the asparagine-linked sugar chains of human chorionic gonadotropin produced in choriocarcinoma. Appearance of triantennary sugar chains and unique biantennary sugar chains","volume":"258","year":"1983","journal-title":"J. Biol. Chem."},{"key":"2023042614592984600_BST-2022-1406C117","doi-asserted-by":"publisher","first-page":"S60","DOI":"10.1016\/j.placenta.2015.02.002","article-title":"Review: hCGs: different sources of production, different glycoforms and functions","volume":"36","year":"2015","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C118","doi-asserted-by":"publisher","first-page":"E240","DOI":"10.1210\/jc.2010-0138","article-title":"Hyperglycosylated hCG is a marker of early human trophoblast invasion","volume":"95","year":"2010","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2023042614592984600_BST-2022-1406C119","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1177\/1933719112461185","article-title":"Siglec-6 expression is increased in placentas from pregnancies complicated by preterm preeclampsia","volume":"20","year":"2013","journal-title":"Reprod. Sci."},{"key":"2023042614592984600_BST-2022-1406C120","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1016\/j.bbrc.2020.09.081","article-title":"Glycosylated Siglec-6 expression in syncytiotrophoblast-derived extracellular vesicles from preeclampsia placentas","volume":"533","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"2023042614592984600_BST-2022-1406C121","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1016\/j.placenta.2009.02.009","article-title":"Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy","volume":"30","year":"2009","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C122","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1002\/uog.3876","article-title":"First-trimester maternal serum PP-13. PAPP-A and second-trimester uterine artery Doppler pulsatility index as markers of pre-eclampsia","volume":"29","year":"2007","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"2023042614592984600_BST-2022-1406C123","doi-asserted-by":"publisher","first-page":"122.e1","DOI":"10.1016\/j.ajog.2008.01.013","article-title":"First-trimester maternal serum PP13 in the risk assessment for preeclampsia","volume":"199","year":"2008","journal-title":"Am. J. Obstet. Gynecol."},{"key":"2023042614592984600_BST-2022-1406C124","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1002\/uog.2686","article-title":"A novel approach to first-trimester screening for early pre-eclampsia combining serum PP-13 and Doppler ultrasound","volume":"27","year":"2006","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"2023042614592984600_BST-2022-1406C125","doi-asserted-by":"publisher","first-page":"35.e1","DOI":"10.1016\/j.ajog.2007.02.025","article-title":"First-trimester placental protein 13 screening for preeclampsia and intrauterine growth restriction","volume":"197","year":"2007","journal-title":"Am. J. Obstet. Gynecol."},{"key":"2023042614592984600_BST-2022-1406C126","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1007\/s00428-008-0658-x","article-title":"Placental protein 13 (galectin-13) has decreased placental expression but increased shedding and maternal serum concentrations in patients presenting with preterm pre-eclampsia and HELLP syndrome","volume":"453","year":"2008","journal-title":"Virchows Arch."},{"key":"2023042614592984600_BST-2022-1406C127","doi-asserted-by":"publisher","first-page":"S30","DOI":"10.1016\/j.placenta.2010.09.006","article-title":"Placenta-bound and body fluid PP13 and its mRNA in normal pregnancy compared to preeclampsia, HELLP and preterm delivery","volume":"32","year":"2011","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C128","doi-asserted-by":"publisher","first-page":"909","DOI":"10.2337\/db10-1186","article-title":"Glycosylation failure extends to glycoproteins in gestational diabetes mellitus: evidence from reduced \u03b12-6 sialylation and impaired immunomodulatory activities of pregnancy-related glycodelin-A","volume":"60","year":"2011","journal-title":"Diabetes"},{"key":"2023042614592984600_BST-2022-1406C129","doi-asserted-by":"publisher","first-page":"758267","DOI":"10.3389\/fimmu.2021.758267","article-title":"Immunobiology of gestational diabetes mellitus in post-Medawar era","volume":"12","year":"2022","journal-title":"Front. Immunol."},{"key":"2023042614592984600_BST-2022-1406C130","doi-asserted-by":"publisher","first-page":"2404","DOI":"10.3390\/ijms21072404","article-title":"Placental galectin-2 expression in gestational diabetes: a systematic, histological analysis","volume":"21","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"2023042614592984600_BST-2022-1406C131","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1093\/molehr\/gau021","article-title":"Getting too sweet: galectin-1 dysregulation in gestational diabetes mellitus","volume":"20","year":"2014","journal-title":"Mol. Hum. Reprod."},{"key":"2023042614592984600_BST-2022-1406C132","doi-asserted-by":"publisher","first-page":"644","DOI":"10.3390\/ijms17050644","article-title":"Prototype and chimera-type galectins in placentas with spontaneous and recurrent miscarriages","volume":"17","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"2023042614592984600_BST-2022-1406C133","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/j.placenta.2004.03.006","article-title":"Galectin-1 and galectin-3 in the trophoblast of the gestational trophoblastic disease","volume":"25","year":"2004","journal-title":"Placenta"},{"key":"2023042614592984600_BST-2022-1406C134","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1385\/ENDO:10:2:137","article-title":"Development and characterization of antibodies to a nicked and hyperglycosylated form of hCG from a choriocarcinoma patient","volume":"10","year":"1999","journal-title":"Endocrine"},{"key":"2023042614592984600_BST-2022-1406C135","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/BF02778058","article-title":"Carbohydrate and peptide structure of the \u03b1- and \u03b2-subunits of human chorionic gonadotropin from normal and aberrant pregnancy and choriocarcinoma","volume":"7","year":"1997","journal-title":"Endocrine"},{"key":"2023042614592984600_BST-2022-1406C136","doi-asserted-by":"publisher","first-page":"4999","DOI":"10.3390\/ijms20204999","article-title":"Dysregulation of placental functions and immune pathways in complete hydatidiform moles","volume":"20","year":"2019","journal-title":"Int. J. Mol. Sci."}],"container-title":["Biochemical Society Transactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/biochemsoctrans\/article-pdf\/51\/2\/639\/945786\/bst-2022-1406.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/biochemsoctrans\/article-pdf\/51\/2\/639\/945786\/bst-2022-1406.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T14:59:51Z","timestamp":1682521191000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/biochemsoctrans\/article\/51\/2\/639\/232771\/Roles-of-N-linked-glycosylation-and-glycan-binding"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,16]]},"references-count":136,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,3,16]]},"published-print":{"date-parts":[[2023,4,26]]}},"URL":"https:\/\/doi.org\/10.1042\/bst20221406","relation":{},"ISSN":["0300-5127","1470-8752"],"issn-type":[{"value":"0300-5127","type":"print"},{"value":"1470-8752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,16]]}}}