{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T16:02:32Z","timestamp":1699113752693},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"1","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1970,1,1]]},"abstract":"<jats:p>1. A considerable increase in the plasminogen activator content in the internal jugular venous blood as compared with that in the arterial blood was found in fifty patients.<\/jats:p>\n               <jats:p>2. Inhalation of 5% carbon dioxide in air was associated with increased plasminogen activator content in blood from the internal jugular vein in all the eight patients treated in this way.<\/jats:p>\n               <jats:p>3. It is suggested that the human brain makes a contribution of plasminogen activator to the circulation of the body and that the amount contributed is determined by the rate of the blood flow.<\/jats:p>","DOI":"10.1042\/cs0380085","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:14:19Z","timestamp":1438942459000},"page":"85-91","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The Brain as Contributor of Plasminogen Activator to the Blood"],"prefix":"10.1042","volume":"38","author":[{"given":"I. Sudhakaran","family":"Menon","sequence":"first","affiliation":[{"name":"Departments of Medicine and Medical Statistics, The Royal Victoria Infirmary and the University of Newcastle upon Tyne, Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Muscat-Baron","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Medical Statistics, The Royal Victoria Infirmary and the University of Newcastle upon Tyne, Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Weightman","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Medical Statistics, The Royal Victoria Infirmary and the University of Newcastle upon Tyne, Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. A.","family":"Dewar","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Medical Statistics, The Royal Victoria Infirmary and the University of Newcastle upon Tyne, Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/38\/1\/85\/723551\/cs0380085.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/38\/1\/85\/723551\/cs0380085.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T11:43:55Z","timestamp":1638445435000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/38\/1\/85\/69557\/The-Brain-as-Contributor-of-Plasminogen-Activator"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1970,1,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0380085","relation":{},"ISSN":["0009-9287"],"issn-type":[{"value":"0009-9287","type":"print"}],"subject":[],"published":{"date-parts":[[1970,1,1]]}}}