{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T07:36:42Z","timestamp":1649144202769},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"6","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1971,12,1]]},"abstract":"<jats:p>1. A previously unidentified compound first observed in the serum of children with kwashiorkor has been isolated from the urine of experimental protein malnourished rats.<\/jats:p>\n               <jats:p>2. On mass spectroscopy and nuclear-magnetic-resonance spectroscopy the unknown compound appeared identical with authentic piperidine-2-carboxylic acid. This identity was confirmed by the behaviour of the unknown and authentic compounds on paper, ion-exchange, thin-layer or gas-liquid chromatography.<\/jats:p>\n               <jats:p>3. The significance of the accumulation of piperidine-2-carboxylic acid in the serum of children with kwashiorkor is discussed.<\/jats:p>","DOI":"10.1042\/cs0410535","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:25:32Z","timestamp":1438943132000},"page":"535-543","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Isolation and Identification of Piperidine-2-Carboxylic Acid in the Urine of Protein Malnourished Rats"],"prefix":"10.1042","volume":"41","author":[{"given":"R. S.","family":"Crowne","sequence":"first","affiliation":[{"name":"Shell Research Ltd, Tunstall Laboratory, Broad Oak Road, Sittingbourne, Kent"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Donninger","sequence":"additional","affiliation":[{"name":"Shell Research Ltd, Tunstall Laboratory, Broad Oak Road, Sittingbourne, Kent"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. F.","family":"Grimble","sequence":"additional","affiliation":[{"name":"Shell Research Ltd, Tunstall Laboratory, Broad Oak Road, Sittingbourne, Kent"},{"name":"MRC Child Nutrition Unit, Mulago Hospital, Kampala, Uganda"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. G.","family":"Whitehead","sequence":"additional","affiliation":[{"name":"Shell Research Ltd, Tunstall Laboratory, Broad Oak Road, Sittingbourne, Kent"},{"name":"MRC Child Nutrition Unit, Mulago Hospital, Kampala, Uganda"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/41\/6\/535\/814398\/cs0410535.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/41\/6\/535\/814398\/cs0410535.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T10:33:43Z","timestamp":1638441223000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/41\/6\/535\/69346\/The-Isolation-and-Identification-of-Piperidine-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971,12,1]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1971,12,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0410535","relation":{},"ISSN":["0009-9287"],"issn-type":[{"value":"0009-9287","type":"print"}],"subject":[],"published":{"date-parts":[[1971,12,1]]}}}