{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T00:53:34Z","timestamp":1695776014401},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"6","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1975,12,1]]},"abstract":"<jats:p>1. Nine patients with clinically unimportant heart disease or benign essential hypertension were given frusemide intravenously during right-heart catheterization.<\/jats:p>\n               <jats:p>2. Pressures in both atria decreased rapidly and in parallel. The magnitude of the pressure decrease was clearly related to decrease in plasma volume loss.<\/jats:p>\n               <jats:p>3. Plasma renin activity increased significantly after 5 min (P &lt; 0\u00b701), but did not correlate with plasma volume loss.<\/jats:p>\n               <jats:p>4. Venous tone in the forearm was unchanged.<\/jats:p>\n               <jats:p>5. It is concluded that the pressure reduction was secondary to plasma volume depletion through diuresis and that increased plasma renin activity was mainly caused by intrarenal changes.<\/jats:p>","DOI":"10.1042\/cs0490551","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T06:29:47Z","timestamp":1438928987000},"page":"551-555","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Early Effects of Intravenous Frusemide on Central Haemodynamics, Venous Tone and Plasma Renin Activity"],"prefix":"10.1042","volume":"49","author":[{"given":"B.","family":"Hesse","sequence":"first","affiliation":[{"name":"Cardiovascular Laboratory, Medical Department B, Rigshospitalet, University of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Cardiovascular Laboratory, Medical Department B, Rigshospitalet, University of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Lund-Jacobsen","sequence":"additional","affiliation":[{"name":"Cardiovascular Laboratory, Medical Department B, Rigshospitalet, University of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/49\/6\/551\/816092\/cs0490551.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/49\/6\/551\/816092\/cs0490551.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T17:07:13Z","timestamp":1571936833000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/49\/6\/551\/70609\/The-Early-Effects-of-Intravenous-Frusemide-on"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,12,1]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1975,12,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0490551","relation":{},"ISSN":["0301-0538"],"issn-type":[{"value":"0301-0538","type":"print"}],"subject":[],"published":{"date-parts":[[1975,12,1]]}}}