{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T18:01:21Z","timestamp":1648749681572},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"4","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1976,4,1]]},"abstract":"<jats:p>1. A patient with polyuria in whom diabetes insipidus had been diagnosed was treated with Pitressin. Resistance to this therapy developed after 18 months and a circulating antibody to vasopressin was then demonstrated. Withdrawal of therapy led to a fall in titre of the antibody and an increase in maximal urinary concentration.<\/jats:p>\n               <jats:p>2. The antibody to vasopressin was associated with the IgA fraction of the serum immunoglobulins and its characteristics are described.<\/jats:p>","DOI":"10.1042\/cs0500277","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:30:40Z","timestamp":1438943440000},"page":"277-283","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Polyuria Associated with an Antibody to Vasopressin"],"prefix":"10.1042","volume":"50","author":[{"given":"G. W.","family":"Bisset","sequence":"first","affiliation":[{"name":"St Thomas' Hospital and Medical School, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Black","sequence":"additional","affiliation":[{"name":"St Thomas' Hospital and Medical School, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. J.","family":"Hilton","sequence":"additional","affiliation":[{"name":"St Thomas' Hospital and Medical School, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. F.","family":"Jones","sequence":"additional","affiliation":[{"name":"St Thomas' Hospital and Medical School, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Montgomery","sequence":"additional","affiliation":[{"name":"St Thomas' Hospital and Medical School, London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/50\/4\/277\/816335\/cs0500277.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/50\/4\/277\/816335\/cs0500277.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T23:02:36Z","timestamp":1571958156000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/50\/4\/277\/70491\/Polyuria-Associated-with-an-Antibody-to"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1976,4,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0500277","relation":{},"ISSN":["0301-0538"],"issn-type":[{"value":"0301-0538","type":"print"}],"subject":[],"published":{"date-parts":[[1976,4,1]]}}}