{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T04:10:59Z","timestamp":1648613459256},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"4","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1976,4,1]]},"abstract":"<jats:p>1. Lipoprotein lipase activity and hormone-sensitive lipase activity were investigated in subcutaneous lipomas removed from two patients and compared with the enzyme activities in subcutaneous adipose tissue from two normal subjects.<\/jats:p>\n               <jats:p>2. Confirmation was obtained of the presence of lipoprotein lipase activity in lipomas with an activity fifteen to forty-five times that in the two control samples.<\/jats:p>\n               <jats:p>3. Hormone-sensitive lipase activity was demonstrated in lipomas under basal conditions of assay as well as in the presence of adrenaline plus theophylline. However, compared with the non-lipomatous fat samples, these activities were lower, as was the magnitude of the lipolytic response to adrenaline plus theophylline.<\/jats:p>\n               <jats:p>4. The significance of these measurements of enzyme activity and their role in the pathogenesis of lipomas are briefly discussed.<\/jats:p>","DOI":"10.1042\/cs0500315","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:30:40Z","timestamp":1438943440000},"page":"315-318","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lipoprotein Lipase and Hormone-Sensitive Lipase Activities in Human Subcutaneous Lipomas: Comparison with Normal Subcutaneous Adipose Tissue"],"prefix":"10.1042","volume":"50","author":[{"given":"Y.","family":"Giudicelli","sequence":"first","affiliation":[{"name":"Service de Biochimie, Centre Hospitaller Intercommunal, Poissy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Pecquery","sequence":"additional","affiliation":[{"name":"Service de Biochimie, Centre Hospitaller Intercommunal, Poissy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Agli","sequence":"additional","affiliation":[{"name":"Service de Biochimie, Centre Hospitaller Intercommunal, Poissy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Jamin","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne, Centre Hospitaller Intercommunal, Poissy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Quevauvilliers","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne, Centre Hospitaller Intercommunal, Poissy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/50\/4\/315\/816375\/cs0500315.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/50\/4\/315\/816375\/cs0500315.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,26]],"date-time":"2019-10-26T07:53:08Z","timestamp":1572076388000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/50\/4\/315\/70518\/Lipoprotein-Lipase-and-HormoneSensitive-Lipase"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1976,4,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0500315","relation":{},"ISSN":["0301-0538"],"issn-type":[{"value":"0301-0538","type":"print"}],"subject":[],"published":{"date-parts":[[1976,4,1]]}}}