{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T14:16:53Z","timestamp":1648909013704},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"s3","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1976,1,1]]},"abstract":"<jats:p>1. Artificial cerebrospinal fluid was perfused through the cerebral ventricles of conscious rats. A basal secretion rate of 16 \u00b1 3 \u00d7 10\u201415 mol of immunoreactive angiotensin 11\/min was calculated for intact rats.<\/jats:p>\n               <jats:p>2. Most of the immunoreactive angiotensin II consisted probably of the heptapeptide or pentapeptide angiotensin II fragments.<\/jats:p>\n               <jats:p>3. The pressor responses to intraventricular perfusions of angiotensin II were normal in Long\u2014Evans rats, virtually absent in rats homozygous for hereditary hypothalamic diabetes insipidus, irrespective of whether they were injected with vasopressin tannate or not, and intermediate in rats heterozygous for hypothalamic diabetes insipidus.<\/jats:p>\n               <jats:p>4. The results suggest that the pressor response to intraventricular angiotensin II is related to the release of vasopressin.<\/jats:p>","DOI":"10.1042\/cs051391s","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:31:32Z","timestamp":1438943492000},"page":"391s-394s","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Intraventricular Perfusion of Angiotensin II in Conscious Normal Rats and in Rats with Hereditary Hypothalamic Diabetes Insipidus"],"prefix":"10.1042","volume":"51","author":[{"given":"J. S.","family":"Hutchinson","sequence":"first","affiliation":[{"name":"Department of Pharmacology, University of Heidelberg, West Germany"},{"name":"Baker Medical Research Institute, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Schelling","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, University of Heidelberg, West Germany"},{"name":"Baker Medical Research Institute, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"M\u00f6hring","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, University of Heidelberg, West Germany"},{"name":"Baker Medical Research Institute, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Ganten","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, University of Heidelberg, West Germany"},{"name":"Baker Medical Research Institute, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/51\/s3\/391s\/817252\/cs051391s.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/51\/s3\/391s\/817252\/cs051391s.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,27]],"date-time":"2019-10-27T18:58:31Z","timestamp":1572202711000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/51\/s3\/391s\/101608\/Effect-of-Intraventricular-Perfusion-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,1,1]]},"references-count":0,"journal-issue":{"issue":"s3","published-print":{"date-parts":[[1976,1,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs051391s","relation":{},"ISSN":["0144-4107"],"issn-type":[{"value":"0144-4107","type":"print"}],"subject":[],"published":{"date-parts":[[1976,1,1]]}}}