{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T07:20:18Z","timestamp":1697354418364},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"5","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1977,5,1]]},"abstract":"<jats:p>1. Five patients with the osteomalacia of chronic renal failure were given 50\u2013100 nmol of 25-hydroxy vitamin D3 intravenously per day for 24\u201328 days.<\/jats:p>\n               <jats:p>2. In all five patients, during administration of 25-hydroxy vitamin D3 there was a substantial rise in the plasma concentration of 25-hydroxy vitamin D from initially abnormally low values.<\/jats:p>\n               <jats:p>3. Significant improvement in bone mineralization, intestinal calcium absorption and muscle strength occurred in the three patients with the greatest rise in plasma 25-hydroxy vitamin D.<\/jats:p>","DOI":"10.1042\/cs0520499","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T06:32:03Z","timestamp":1438929123000},"page":"499-508","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Effect of 25-Hydroxy Vitamin D3 in the Osteomalacia of Chronic Renal Failure"],"prefix":"10.1042","volume":"52","author":[{"given":"J. B.","family":"Eastwood","sequence":"first","affiliation":[{"name":"Charing Cross Hospital Medical School, London, Centre Andr\u00e9 Lichtwitz (INSERM), H\u00f4pital Lariboisi\u00e8re, Paris, France, Royal National Orthopaedic Hospital, London, and Mayo Clinic, Mayo Foundation, Rochester, Minnesota, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. C. B.","family":"Stamp","sequence":"additional","affiliation":[{"name":"Charing Cross Hospital Medical School, London, Centre Andr\u00e9 Lichtwitz (INSERM), H\u00f4pital Lariboisi\u00e8re, Paris, France, Royal National Orthopaedic Hospital, London, and Mayo Clinic, Mayo Foundation, Rochester, Minnesota, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. E.","family":"De Wardener","sequence":"additional","affiliation":[{"name":"Charing Cross Hospital Medical School, London, Centre Andr\u00e9 Lichtwitz (INSERM), H\u00f4pital Lariboisi\u00e8re, Paris, France, Royal National Orthopaedic Hospital, London, and Mayo Clinic, Mayo Foundation, Rochester, Minnesota, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. J.","family":"Bordier","sequence":"additional","affiliation":[{"name":"Charing Cross Hospital Medical School, London, Centre Andr\u00e9 Lichtwitz (INSERM), H\u00f4pital Lariboisi\u00e8re, Paris, France, Royal National Orthopaedic Hospital, London, and Mayo Clinic, Mayo Foundation, Rochester, Minnesota, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. D.","family":"Arnaud","sequence":"additional","affiliation":[{"name":"Charing Cross Hospital Medical School, London, Centre Andr\u00e9 Lichtwitz (INSERM), H\u00f4pital Lariboisi\u00e8re, Paris, France, Royal National Orthopaedic Hospital, London, and Mayo Clinic, Mayo Foundation, Rochester, Minnesota, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/52\/5\/499\/739437\/cs0520499.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/52\/5\/499\/739437\/cs0520499.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T23:35:58Z","timestamp":1572046558000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/52\/5\/499\/70816\/The-Effect-of-25Hydroxy-Vitamin-D3-in-the"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,5,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1977,5,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0520499","relation":{},"ISSN":["0301-0538"],"issn-type":[{"value":"0301-0538","type":"print"}],"subject":[],"published":{"date-parts":[[1977,5,1]]}}}