{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T19:04:42Z","timestamp":1649185482797},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"5","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1978,5,1]]},"abstract":"<jats:p>1. Experiments were carried out in dogs in which renal perfusion pressure was reduced 40 min before beginning expansion of the extracellular fluid space by 10% with isotonic sodium chloride solution. Sodium excretion increased up to 590% of control values in spite of the fact that the filtered load of sodium was below that of the control period and circulating mineralocorticoids were not suppressed.<\/jats:p>\n               <jats:p>2. The findings indicate that, in the dog, prior exposure of the kidney to the volume-expanded state is not a prerequisite for natriuresis to occur.<\/jats:p>","DOI":"10.1042\/cs0540525","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T06:34:03Z","timestamp":1438929243000},"page":"525-527","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Saline-Induced Natriuresis in the Dog without Prior Exposure of the Kidney to the Physical Effects of Expansion of the Extracellular Fluid Compartment"],"prefix":"10.1042","volume":"54","author":[{"given":"P. J.","family":"Klemmer","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"De Los Santos","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. B.","family":"Blythe","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/54\/5\/525\/740261\/cs0540525.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/54\/5\/525\/740261\/cs0540525.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,27]],"date-time":"2019-10-27T04:36:49Z","timestamp":1572151009000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/54\/5\/525\/71210\/SalineInduced-Natriuresis-in-the-Dog-without-Prior"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,5,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1978,5,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0540525","relation":{},"ISSN":["0301-0538"],"issn-type":[{"value":"0301-0538","type":"print"}],"subject":[],"published":{"date-parts":[[1978,5,1]]}}}