{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T13:22:36Z","timestamp":1756992156049},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"s6","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1980,12,1]]},"abstract":"<jats:p>1. Structural and functional changes resulting from baroreceptor denervation were studied in rabbits 4 days after surgery.<\/jats:p>\n               <jats:p>2. After section of the aortic and carotid sinus nerves, arterial pressure was characteristically labile although the mean pressures were not significantly different from those of control animals.<\/jats:p>\n               <jats:p>3. The responsiveness of isolated ear arteries and cephalic veins from deafferented animals to noradrenaline and electrical stimulation of their sympathetic innervation was similar in both groups.<\/jats:p>\n               <jats:p>4. Neuronal uptake of noradrenaline into arterial tissue was similar in both groups, although uptake into the cephalic veins of deafferented animals was less than in the control group.<\/jats:p>\n               <jats:p>5. [3H]Thymidine uptake, an index of DNA synthesis, was similar in both groups, radioautography revealing no difference in smooth muscle cell labelling.<\/jats:p>\n               <jats:p>6. Uptake of [3H]proline, an indicator of protein synthesis, by aorta, ear, brachial, basilar and renal arteries from deafferented animals was greater than in control animals.<\/jats:p>\n               <jats:p>7. Baroreceptor denervation altered protein metabolism in the arterial wall.<\/jats:p>","DOI":"10.1042\/cs059327s","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:36:24Z","timestamp":1438943784000},"page":"327s-329s","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Rapid Onset of Vascular Wall Protein Synthesis with Increase in Lability of Blood Pressure in Rabbits"],"prefix":"10.1042","volume":"59","author":[{"given":"A. G.","family":"MacLean","sequence":"first","affiliation":[{"name":"Departments of Pharmacology and Oral Biology, Schools of Medicine and Dentistry, University of California, Los Angeles, Los Angeles, California U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. D.","family":"Bevan","sequence":"additional","affiliation":[{"name":"Departments of Pharmacology and Oral Biology, Schools of Medicine and Dentistry, University of California, Los Angeles, Los Angeles, California U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. R.","family":"Hume","sequence":"additional","affiliation":[{"name":"Departments of Pharmacology and Oral Biology, Schools of Medicine and Dentistry, University of California, Los Angeles, Los Angeles, California U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. W.","family":"Ransom","sequence":"additional","affiliation":[{"name":"Departments of Pharmacology and Oral Biology, Schools of Medicine and Dentistry, University of California, Los Angeles, Los Angeles, California U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. A.","family":"Bevan","sequence":"additional","affiliation":[{"name":"Departments of Pharmacology and Oral Biology, Schools of Medicine and Dentistry, University of California, Los Angeles, Los Angeles, California U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/59\/s6\/327s\/876437\/cs059327s.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/59\/s6\/327s\/876437\/cs059327s.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T21:23:38Z","timestamp":1638480218000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/59\/s6\/327s\/102526\/Rapid-Onset-of-Vascular-Wall-Protein-Synthesis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,12,1]]},"references-count":0,"journal-issue":{"issue":"s6","published-print":{"date-parts":[[1980,12,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs059327s","relation":{},"ISSN":["0144-9664"],"issn-type":[{"value":"0144-9664","type":"print"}],"subject":[],"published":{"date-parts":[[1980,12,1]]}}}