{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:50:19Z","timestamp":1757703019618},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"2","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1982,2,1]]},"abstract":"<jats:p>1. The changes in heart rate surrounding a period of apnoeic asphyxia, produced by either central or obstructive sleep apnoea, are characteristically a progressive bradycardia during the apnoeic period followed by an abrupt reversal to tachycardia with resumption of lung inflation.<\/jats:p>\n               <jats:p>2. In a subject who had undergone bilateral pulmonary vagotomy with sparing of the cardiac branches on the left side, the bradycardia is still present during the apnoeic period; however, there is no abrupt response to lung inflation.<\/jats:p>\n               <jats:p>3. A subject who had undergone unilateral right-sided pulmonary vagotomy demonstrated a normal response, the increase in heart rate coinciding with resumption of airflow.<\/jats:p>\n               <jats:p>4. These findings are consistent with the hypothesis that the bradycardia of sleep apnoea is a hypoxia-induced chemoreflex and that reversal to tachycardia with resumption of lung inflation is a reflex with afferent fibres in the pulmonary vagus nerves.<\/jats:p>","DOI":"10.1042\/cs0620163","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:39:49Z","timestamp":1438943989000},"page":"163-167","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Influence of the Vagus Nerve on Changes in Heart Rate during Sleep Apnoea in Man"],"prefix":"10.1042","volume":"62","author":[{"given":"C. I.","family":"Meanock","sequence":"first","affiliation":[{"name":"Midhurst Medical Research Institute, Midhurst, West Sussex, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/62\/2\/163\/460454\/cs0620163.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/62\/2\/163\/460454\/cs0620163.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T21:05:46Z","timestamp":1638479146000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/62\/2\/163\/91934\/Influence-of-the-Vagus-Nerve-on-Changes-in-Heart"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1982,2,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0620163","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,2,1]]}}}