{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T15:41:55Z","timestamp":1762875715728},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"4","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1982,4,1]]},"abstract":"<jats:p>1. The response to exogenous parathyroid hormone (PTH) was tested in normal subjects and patients with osteomalacia due to vitamin D deficiency; 200 MRC units of bovine PTH were administered intravenously.<\/jats:p>\n               <jats:p>2. The rise in plasma adenosine 3\u2032:5\u2032-cyclic monophosphate (cyclic AMP) and the increase in urinary excretion of cyclic AMP were reduced in the patients with vitamin D deficiency. After treatment with vitamin D the responses returned to normal.<\/jats:p>\n               <jats:p>3. It is suggested that this reversible resistance is due to the secondary hyperparathyroidism associated with vitamin D deficiency.<\/jats:p>","DOI":"10.1042\/cs0620381","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:39:49Z","timestamp":1438943989000},"page":"381-387","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Reversible Resistance to the Renal Action of Parathyroid Hormone in Human Vitamin D Deficiency"],"prefix":"10.1042","volume":"62","author":[{"given":"I. G.","family":"Lewin","sequence":"first","affiliation":[{"name":"Department of Medicine, The Middlesex Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. E.","family":"Papapoulos","sequence":"additional","affiliation":[{"name":"Department of Medicine, The Middlesex Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. N.","family":"Hendy","sequence":"additional","affiliation":[{"name":"Department of Medicine, The Middlesex Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Tomlinson","sequence":"additional","affiliation":[{"name":"Department of Medicine, The Middlesex Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. L. H.","family":"O'riordan","sequence":"additional","affiliation":[{"name":"Department of Medicine, The Middlesex Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/62\/4\/381\/453182\/cs0620381.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/62\/4\/381\/453182\/cs0620381.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T20:06:13Z","timestamp":1638475573000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/62\/4\/381\/72423\/Reversible-Resistance-to-the-Renal-Action-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1982,4,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0620381","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,4,1]]}}}