{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:30:46Z","timestamp":1760189446715},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"5","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1983,11,1]]},"abstract":"<jats:p>1. Filterability (deformability) of erythrocytes of patients with Raynaud's phenomenon together with progressive systemic sclerosis (PSS) was decreased compared with the filtration of erythrocytes from normal subjects.<\/jats:p>\n               <jats:p>2. PSS erythrocytes showed lower electrophoretic velocity and about 23% less neuraminidase-removable sialic acid density on their surface than the normal erythrocytes.<\/jats:p>\n               <jats:p>3. PSS erythrocytes showed more adherence to cultured endothelial cells than the control normal erythrocytes.<\/jats:p>\n               <jats:p>4. It is concluded that the increased rigidity and adherence of PSS erythrocytes-5-have pathological significance in the mechanism of vascular abnormalities in PSS.<\/jats:p>","DOI":"10.1042\/cs0650515","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:46:18Z","timestamp":1438944378000},"page":"515-519","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Altered Behaviour of Erythrocytes in Scleroderma"],"prefix":"10.1042","volume":"65","author":[{"given":"I. B.","family":"Kovacs","sequence":"first","affiliation":[{"name":"Departments of Dermatology, St Bartholomew's Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. O.","family":"Sowemimo-Coker","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology, St Bartholomew's Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. D. T.","family":"Kirby","sequence":"additional","affiliation":[{"name":"Departments of Dermatology, St Bartholomew's Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Turner","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology, St Bartholomew's Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/65\/5\/515\/454324\/cs0650515.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/65\/5\/515\/454324\/cs0650515.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T20:28:52Z","timestamp":1638476932000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/65\/5\/515\/73315\/Altered-Behaviour-of-Erythrocytes-in-Scleroderma"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,11,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1983,11,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0650515","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,11,1]]}}}