{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T14:01:02Z","timestamp":1649080862688},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"5","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1984,5,1]]},"abstract":"<jats:p>1. Urinary sodium excretion in anaesthetized rats subjected to high-sodium artificial cerebrospinal fluid (CSF) infusion into the lateral brain ventricle, was significantly higher than in rats infused with normal-sodium CSF.<\/jats:p>\n               <jats:p>2. Urinary immunoreactive 6-ketoprostaglandin F1\u03b1, the stable derivative of prostacyclin, was significantly reduced in the high-sodium CSF group, as compared with the normal-sodium CSF group.<\/jats:p>\n               <jats:p>3. When dog aortic endothelium was incubated in the presence of plasma, endothelial prostacyclin production was found to be inhibited by plasma from rats infused with high-sodium CSF compared with the effect of plasma from the rats infused with normal-sodium CSF.<\/jats:p>\n               <jats:p>4. Our results indicate that intracerebroventricular infusion of high-sodium CSF induces a natriuretic response and is associated with the appearance of a humoral factor which blocks prostacyclin byosynthesis.<\/jats:p>","DOI":"10.1042\/cs0660621","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:50:35Z","timestamp":1438944635000},"page":"621-624","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Intracerebroventricular Infusion of Sodium Chloride-Rich Artificial Cerebrospinal Fluid in Rats Induces Natriuresis and Releases An Inhibitor of Prostaglandin Synthesis"],"prefix":"10.1042","volume":"66","author":[{"given":"Javier","family":"Diez","sequence":"first","affiliation":[{"name":"Department of Medicine, University Clinic, University of Navarra, Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inmaculada","family":"Colina","sequence":"additional","affiliation":[{"name":"Department of Medicine, University Clinic, University of Navarra, Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Guarner","sequence":"additional","affiliation":[{"name":"Department of Medicine, University Clinic, University of Navarra, Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Quiroga","sequence":"additional","affiliation":[{"name":"Department of Medicine, University Clinic, University of Navarra, Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio","family":"Corzo","sequence":"additional","affiliation":[{"name":"Department of Medicine, University Clinic, University of Navarra, Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9s","family":"Purroy","sequence":"additional","affiliation":[{"name":"Department of Medicine, University Clinic, University of Navarra, Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Prieto","sequence":"additional","affiliation":[{"name":"Department of Medicine, University Clinic, University of Navarra, Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/66\/5\/621\/455222\/cs0660621.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/66\/5\/621\/455222\/cs0660621.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T20:36:14Z","timestamp":1638477374000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/66\/5\/621\/73523\/Intracerebroventricular-Infusion-of-Sodium"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,5,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1984,5,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0660621","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,5,1]]}}}