{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T01:51:27Z","timestamp":1648605087758},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"5","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1985,5,1]]},"abstract":"<jats:p>1. We studied renin-aldosterone system behaviour in five renovascular hypertensive patients during central hypervolaemia by water immersion to the neck.<\/jats:p>\n               <jats:p>2. Water immersion significantly suppressed the high peripheral renin levels of the patients despite an autonomic renin secretion from the stenotic kidney, a significant reduction of mean blood pressure and an increase in distal tubule sodium concentration.<\/jats:p>\n               <jats:p>3. The effect of immersion on plasma aldosterone appeared to be primarily mediated via suppression of plasma renin activity (PRA).<\/jats:p>\n               <jats:p>4. Our data suggest that: (a) the renin secretion is mainly modulated by cardiopulmonary receptors activity; (b) the neurogenic reflex control of plasma renin activity is very effective in renovascular hypertension.<\/jats:p>","DOI":"10.1042\/cs0680609","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T10:57:35Z","timestamp":1438945055000},"page":"609-612","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Renin-aldosterone system suppression during water immersion in renovascular hypertension"],"prefix":"10.1042","volume":"68","author":[{"given":"P.","family":"Coruzzi","sequence":"first","affiliation":[{"name":"Institute of Semeiotica Medica, University of Parma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Biggi","sequence":"additional","affiliation":[{"name":"Institute of Semeiotica Medica, University of Parma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Musiari","sequence":"additional","affiliation":[{"name":"Institute of Semeiotica Medica, University of Parma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ravanetti","sequence":"additional","affiliation":[{"name":"Institute of Semeiotica Medica, University of Parma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Novarini","sequence":"additional","affiliation":[{"name":"Institute of Semeiotica Medica, University of Parma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/68\/5\/609\/451314\/cs0680609.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/68\/5\/609\/451314\/cs0680609.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T20:38:51Z","timestamp":1638477531000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/68\/5\/609\/73658\/Renin-aldosterone-system-suppression-during-water"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,5,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1985,5,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0680609","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,5,1]]}}}