{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T23:35:00Z","timestamp":1723160100860},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"4","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1986,4,1]]},"abstract":"<jats:p>1. Plasma adenosine, inosine and hypoxanthine concentrations were assayed in seven control subjects, five myoadenylate deaminase deficient (MADD) patients and six McArdle patients before and after ischaemic forearm exercise.<\/jats:p>\n               <jats:p>2. The plasma adenosine increase was very low in all test groups and there were no significant differences.<\/jats:p>\n               <jats:p>3. The MADD patients showed a significantly lower increase of plasma inosine and hypoxanthine after exercise as compared with the controls.<\/jats:p>\n               <jats:p>4. In the McArdle patients the increase in plasma inosine and hypoxanthine after exercise did not differ significantly from the values measured in the controls.<\/jats:p>\n               <jats:p>5. The ischaemic exercise test with measurement of plasma inosine and hypoxanthine might be of diagnostic value in MADD, but not in McArdle's disease.<\/jats:p>","DOI":"10.1042\/cs0700399","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T11:04:05Z","timestamp":1438945445000},"page":"399-401","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Ischaemic exercise test in myoadenylate deaminase deficiency and McArdle's disease: measurement of plasma adenosine, inosine and hypoxanthine"],"prefix":"10.1042","volume":"70","author":[{"given":"S. P. T.","family":"Sinkeler","sequence":"first","affiliation":[{"name":"Departments of Neurology, Physiology and Human Genetics, St Radboud Hospital, University of Nijmegen, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. M. G.","family":"Joosten","sequence":"additional","affiliation":[{"name":"Departments of Neurology, Physiology and Human Genetics, St Radboud Hospital, University of Nijmegen, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A.","family":"Wevers","sequence":"additional","affiliation":[{"name":"Departments of Neurology, Physiology and Human Genetics, St Radboud Hospital, University of Nijmegen, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A.","family":"Binkhorst","sequence":"additional","affiliation":[{"name":"Departments of Neurology, Physiology and Human Genetics, St Radboud Hospital, University of Nijmegen, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. T.","family":"Oerlemans","sequence":"additional","affiliation":[{"name":"Departments of Neurology, Physiology and Human Genetics, St Radboud Hospital, University of Nijmegen, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. A.","family":"van Bennekom","sequence":"additional","affiliation":[{"name":"Departments of Neurology, Physiology and Human Genetics, St Radboud Hospital, University of Nijmegen, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. M.","family":"Coerwinkel","sequence":"additional","affiliation":[{"name":"Departments of Neurology, Physiology and Human Genetics, St Radboud Hospital, University of Nijmegen, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. L.","family":"Oei","sequence":"additional","affiliation":[{"name":"Departments of Neurology, Physiology and Human Genetics, St Radboud Hospital, University of Nijmegen, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/70\/4\/399\/456629\/cs0700399.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/70\/4\/399\/456629\/cs0700399.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T20:40:22Z","timestamp":1638477622000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/70\/4\/399\/73807\/Ischaemic-exercise-test-in-myoadenylate-deaminase"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1986,4,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0700399","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,4,1]]}}}