{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T19:48:10Z","timestamp":1759693690757},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"4","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1987,4,1]]},"abstract":"<jats:p>1. The ulcerogenic and protective effects of various rice fractions in the diet were studied in the pylorus ligated ulcer model in the rat.<\/jats:p>\n               <jats:p>2. Oil present in rice and particularly rice bran becomes ulcerogenic on storage and in this model results in a significant increase in the median (range) numbers of ulcers from six (one to ten) to nine (six to 15) (P &amp;gt; 0.05). The ulcerogenic effect of stored rice bran oil was reversed by cysteine which significantly reduced the ulcer incidence from 100% to 60% (P &amp;gt; 0.005) and the numbers of ulcers from 26 (six to 70) to one (zero to four) (P &amp;gt; 0.001).<\/jats:p>\n               <jats:p>3. Fresh rice bran significantly reduced the numbers of ulcers from six (one to ten) to one (one to four) (P &amp;gt; 0.05). Similarly, unmilled rice and freshly milled newly harvested rice was also shown to be protective in this model by significantly reducing the ulcer incidence from 87.5% to 50% and 0% respectively (P values &amp;gt; 0.025) and the numbers of ulcers from three (zero to 17) to one (zero to one) and zero (zero to zero) respectively (P values &amp;gt; 0.001).<\/jats:p>\n               <jats:p>4. These results could in part explain the geographical distribution of duodenal ulceration, where the incidence is high in all the rice eating areas of the world, and provide a plausible hypothesis to explain the mechanism of dietary ulcerogenesis.<\/jats:p>","DOI":"10.1042\/cs0720463","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T11:11:45Z","timestamp":1438945905000},"page":"463-466","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The ulcerogenic and protective action of rice and rice fractions in experimental peptic ulceration"],"prefix":"10.1042","volume":"72","author":[{"given":"A. P.","family":"Jayaraj","sequence":"first","affiliation":[{"name":"Departments of Surgery, Faculty of Clinical Sciences, University College London, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. I.","family":"Tovey","sequence":"additional","affiliation":[{"name":"Departments of Surgery, Faculty of Clinical Sciences, University College London, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. G.","family":"Clark","sequence":"additional","affiliation":[{"name":"Departments of Surgery, Faculty of Clinical Sciences, University College London, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. R.","family":"Rees","sequence":"additional","affiliation":[{"name":"Biochemical Pathology, Faculty of Clinical Sciences, University College London, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. S.","family":"White","sequence":"additional","affiliation":[{"name":"Biochemical Pathology, Faculty of Clinical Sciences, University College London, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. R.","family":"Lewin","sequence":"additional","affiliation":[{"name":"Departments of Surgery, Faculty of Clinical Sciences, University College London, London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/72\/4\/463\/457654\/cs0720463.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/72\/4\/463\/457654\/cs0720463.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T20:44:51Z","timestamp":1638477891000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/72\/4\/463\/74162\/The-ulcerogenic-and-protective-action-of-rice-and"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1987,4,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0720463","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,4,1]]}}}