{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T02:47:55Z","timestamp":1761101275774},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"6","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1987,12,1]]},"abstract":"<jats:p>1. Chronic alcoholism is associated with a selective atrophy of type II skeletal muscle fibres. We studied the glucocorticoid status of chronic alcoholics with and without myopathy to determine if hypercortisolism is responsible for the myopathy.<\/jats:p>\n               <jats:p>2. Twenty-four hour urinary Cortisol excretion and diurnal serum Cortisol measurements were not significantly different in chronic alcoholics, with and without atrophy of type II skeletal muscle fibres.<\/jats:p>\n               <jats:p>3. Diurnal serum Cortisol variation was normal for both groups of alcoholics studied. None of the patients with myopathy had raised serum Cortisol levels.<\/jats:p>\n               <jats:p>4. We conclude that chronic alcoholic myopathy is not due to alcohol-related pseudo-Cushing's syndrome.<\/jats:p>","DOI":"10.1042\/cs0730601","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T11:13:01Z","timestamp":1438945981000},"page":"601-603","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Glucocorticosteroid status in chronic alcoholics with and without skeletal muscle myopathy"],"prefix":"10.1042","volume":"73","author":[{"given":"P.","family":"Duane","sequence":"first","affiliation":[{"name":"Division of Clinical Cell Biology, MRC Clinical Research Centre, Harrow, Middx., U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. J.","family":"Peters","sequence":"additional","affiliation":[{"name":"Division of Clinical Cell Biology, MRC Clinical Research Centre, Harrow, Middx., U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/73\/6\/601\/458618\/cs0730601.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/73\/6\/601\/458618\/cs0730601.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T22:22:30Z","timestamp":1638397350000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/73\/6\/601\/74258\/Glucocorticosteroid-status-in-chronic-alcoholics"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,12,1]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1987,12,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0730601","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,12,1]]}}}