{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:21:19Z","timestamp":1790799679646,"version":"4.1.0"},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"4","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1989,10,1]]},"abstract":"<jats:p>1. Plasma levels of atrial natriuretic peptide (ANP) were measured in seven patients with obstructive sleep apnoea (OSA) while they were awake, during repetitive apnoea and during treatment with nasal continuous positive airway pressure (CPAP).<\/jats:p>\n               <jats:p>2. ANP levels in both pulmonary artery and peripheral venous samples were elevated during apnoeic sleep and reduced when apnoea was prevented by nasal CPAP. Mean values of pulmonary artery ANP were 116.3 \u00b1 17.9 pg\/ml during apnoea and 64.8 \u00b1 15.2 pg\/ml (P &amp;lt; 0.05) on nasal CPAP.<\/jats:p>\n               <jats:p>3. It is concluded that there is increased ANP release during sleep in patients with OSA and that CPAP treatment normalizes ANP secretion. These findings may explain previously identified urinary abnormalities in OSA.<\/jats:p>","DOI":"10.1042\/cs0770407","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T11:29:18Z","timestamp":1438946958000},"page":"407-411","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":113,"title":["Atrial Natriuretic Peptide Release during Sleep in Patients with Obstructive Sleep Apnoea before and during Treatment with Nasal Continuous Positive Airway Pressure"],"prefix":"10.1042","volume":"77","author":[{"given":"J.","family":"Krieger","sequence":"first","affiliation":[{"name":"Sleep Unit, Sydney, Australia"},{"name":"University Hospital, Strasbourg, France"},{"name":"David Read Laboratory, Department of Medicine, University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Laks","sequence":"additional","affiliation":[{"name":"Sleep Unit, Sydney, Australia"},{"name":"David Read Laboratory, Department of Medicine, University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Wilcox","sequence":"additional","affiliation":[{"name":"Sleep Unit, Sydney, Australia"},{"name":"David Read Laboratory, Department of Medicine, University of Sydney, Sydney, Australia"},{"name":"Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. R.","family":"Grunstein","sequence":"additional","affiliation":[{"name":"Sleep Unit, Sydney, Australia"},{"name":"David Read Laboratory, Department of Medicine, University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. J. V.","family":"Costas","sequence":"additional","affiliation":[{"name":"Sleep Unit, Sydney, Australia"},{"name":"David Read Laboratory, Department of Medicine, University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. G.","family":"McDougall","sequence":"additional","affiliation":[{"name":"Howard Florey Institute, University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. E.","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Sleep Unit, Sydney, Australia"},{"name":"David Read Laboratory, Department of Medicine, University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/77\/4\/407\/459947\/cs0770407.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/77\/4\/407\/459947\/cs0770407.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T22:29:39Z","timestamp":1638397779000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/77\/4\/407\/74842\/Atrial-Natriuretic-Peptide-Release-during-Sleep-in"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,10,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1989,10,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0770407","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,10,1]]}}}