{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T15:40:16Z","timestamp":1768923616726,"version":"3.49.0"},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"4","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1993,4,1]]},"abstract":"<jats:p>1. This study was designed to investigate the influence of insulin and glucose on the distribution of trivalent chromium in human plasma and blood cells and in human and rat insulin-sensitive and -insensitive tissues.<\/jats:p>\n               <jats:p>2. Evidence is provided that, in the rat in vitro, a clear difference exists in chromium binding between insulin-sensitive and -insensitive tissues in that chromium binding is significantly enhanced by glucose in insulin-sensitive tissues.<\/jats:p>\n               <jats:p>3. Glucose-dependent association of chromium with human adipose tissue was blocked by inhibitors of glucose transport.<\/jats:p>\n               <jats:p>4. Addition of insulin slightly increased the response to glucose in muscle and reduced the response to glucose in adipose tissue; such effects were less marked than those seen in response to glucose alone.<\/jats:p>\n               <jats:p>5. The results of this study in vitro support the hypothesis that, in vivo, chromium translocates from the blood compartment to insulin-sensitive tissues.<\/jats:p>","DOI":"10.1042\/cs0840477","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T11:34:58Z","timestamp":1438947298000},"page":"477-482","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Glucose-Dependent Uptake of Chromium in Human and Rat Insulin-Sensitive Tissues"],"prefix":"10.1042","volume":"84","author":[{"given":"Brian W.","family":"Morris","sequence":"first","affiliation":[{"name":"Department of Clinical Chemistry, Northern General Hospital, Sheffield, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trevor A.","family":"Gray","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry, Northern General Hospital, Sheffield, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila","family":"MacNeil","sequence":"additional","affiliation":[{"name":"University Department of Medicine, Clinical Sciences Centre, Northern General Hospital, Sheffield, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/84\/4\/477\/464114\/cs0840477.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/84\/4\/477\/464114\/cs0840477.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T22:42:44Z","timestamp":1638398564000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/84\/4\/477\/75955\/Glucose-Dependent-Uptake-of-Chromium-in-Human-and"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1993,4,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0840477","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,4,1]]}}}