{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:22:21Z","timestamp":1778685741404,"version":"3.51.4"},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"1","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1997,1,1]]},"abstract":"<jats:p>1. To investigate the effect of dietary fat source on host resistance to intracellular pathogens, weanling female C3H\/Hen mice were fed one of three experimental diets containing, 20% by weight, lard, soybean oil or 17% menhaden fish oil plus 3% corn oil. After 4 weeks, survival of mice (n = 12\/treatment group) injected intraperitoneally with 2 \u00d7 106 colony forming units of live Listeria monocytogenes was determined. In a second study, bacterial clearance from the liver and spleen at 2, 4 and 7 days post-challenge was determined (n = 8\/treatment group).<\/jats:p>\n               <jats:p>2. We found that the survival of mice fed the diets with soybean oil or menhaden fish oil was significantly lower than those fed lard (P &amp;lt; 0.05). Survival rates were 58% (7\/12), 33% (4\/12) and 100% (12\/12), respectively, for mice fed soybean oil, menhaden fish oil and lard. In the second study, mice fed menhaden fish oil had approximately 1 login greater bacteria in their spleens at day 4 than mice fed lard or soybean oil (P &amp;lt; 0.001). There were no significant treatment differences in the number of bacteria recovered from liver samples.<\/jats:p>\n               <jats:p>3. In summary, dietary fat source significantly affects murine resistance to Listeria, with diets rich in n-3 polyunsaturated fatty acids, such as from fish oil, having the most detrimental effect.<\/jats:p>","DOI":"10.1042\/cs0920095","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T11:39:42Z","timestamp":1438947582000},"page":"95-101","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":81,"title":["Dietary Fish Oil Reduces Survival and Impairs Bacterial Clearance in C3H\/Hen Mice Challenged with <i>Listeria Monocytogenes<\/i>"],"prefix":"10.1042","volume":"92","author":[{"given":"K. L.","family":"Fritsche","sequence":"first","affiliation":[{"name":"Department of Animal Sciences, University of Missouri, Columbia, Missouri, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. M.","family":"Shahbazian","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, University of Missouri, Columbia, Missouri, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, University of Missouri, Columbia, Missouri, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. N.","family":"Berg","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, U.S.A."},{"name":"Department of Animal Sciences, University of Missouri, Columbia, Missouri, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/92\/1\/95\/466465\/cs0920095.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/92\/1\/95\/466465\/cs0920095.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T23:19:14Z","timestamp":1638400754000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/92\/1\/95\/77038\/Dietary-Fish-Oil-Reduces-Survival-and-Impairs"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1997,1,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0920095","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,1,1]]}}}