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PE patients exhibit sympathetic overactivation, in comparison with both normotensive pregnant and hypertensive non-pregnant females. Moreover, PE diminishes baroreceptor reflex sensitivity (BRS) beyond that observed in healthy pregnancy. The absence of the cardiovascular adaptations to pregnancy, combined with sympathovagal imbalance and a blunted BRS leads to life-threatening neurological outcomes. Behaviourally, the increased incidences of maternal depression, anxiety and post-traumatic stress disorder (PTSD) in PE are correlated to low fetal birth weight, intrauterine growth restriction (IUGR) and premature birth. This review addresses these neurological consequences of PE that present in the gravid female both during and after the index pregnancy.<\/jats:p>","DOI":"10.1042\/cs20160108","type":"journal-article","created":{"date-parts":[[2016,7,8]],"date-time":"2016-07-08T01:23:53Z","timestamp":1467941033000},"page":"1417-1434","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Preeclampsia and the brain: neural control of cardiovascular changes during pregnancy and neurological outcomes of preeclampsia"],"prefix":"10.1042","volume":"130","author":[{"given":"Omar\u00a0C.","family":"Logue","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Mississippi Medical Center, Jackson, MS 39216, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric\u00a0M.","family":"George","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of Mississippi Medical Center, Jackson, MS 39216, U.S.A."},{"name":"Department of Biochemistry, University of Mississippi Medical Center, Jackson, MS 39216, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Gene\u00a0L.","family":"Bidwell","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Mississippi Medical Center, Jackson, MS 39216, U.S.A."},{"name":"Department of Biochemistry, University of Mississippi Medical Center, Jackson, MS 39216, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","published-online":{"date-parts":[[2016,7,7]]},"reference":[{"key":"2021113010415011500_B1","doi-asserted-by":"publisher","first-page":"f6564","DOI":"10.1136\/bmj.f6564","article-title":"Pre-eclampsia rates in the United States, 1980\u20132010: age-period-cohort analysis","volume":"347","author":"Ananth","year":"2013","journal-title":"BMJ"},{"key":"2021113010415011500_B2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ejogrb.2013.05.005","article-title":"Global and regional estimates of preeclampsia and eclampsia: a systematic review","volume":"170","author":"Abalos","year":"2013","journal-title":"Eur. 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