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Comprehensive understanding of the molecular mechanisms of antifungal resistance is essential for identification of novel targets that do not promote or delay emergence of drug resistance. The present study discusses features and limitations of the currently available antifungals, mechanisms of antifungal resistance and highlights the emerging therapeutic strategies that could be deployed to combat MDR.<\/jats:p>","DOI":"10.1042\/ebc20160067","type":"journal-article","created":{"date-parts":[[2017,3,3]],"date-time":"2017-03-03T11:55:13Z","timestamp":1488542113000},"page":"157-166","update-policy":"http:\/\/dx.doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Resistance to antifungal therapies"],"prefix":"10.1042","volume":"61","author":[{"given":"Rajendra","family":"Prasad","sequence":"additional","affiliation":[{"name":"Institute of Integrative Sciences and Health and Institute of Biotechnology, Amity University Haryana, Amity Education Valley, Gurgaon, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atanu","family":"Banerjee","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Jawaharlal Nehru University, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul\u00a0Haseeb","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Bioresources, University of Kashmir, Srinagar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"288","published-online":{"date-parts":[[2017,3,3]]},"reference":[{"key":"2021111610241638100_B1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ddtec.2014.02.005","article-title":"Overcoming antifungal resistance","volume":"11","author":"Srinivasan","year":"2014","journal-title":"Drug Discov. 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