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Examination of the relationship among several of these seemingly unrelated molecules depicts a forked pathway comprising at least two branches of equal importance to SAR. One branch is regulated by the plant hormone salicylic acid (SA), and the other culminates (based on current knowledge) with the phosphorylated sugar derivative, glycerol-3-phosphate (G3P). This review summarizes the activities that contribute to pathogen-responsive generation of SA and G3P and the components that regulate their systemic transport during SAR.<\/jats:p>","DOI":"10.1042\/ebc20210098","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T09:36:06Z","timestamp":1659519366000},"page":"673-681","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Systemic acquired resistance-associated transport and metabolic regulation of salicylic acid and glycerol-3-phosphate"],"prefix":"10.1042","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5215-0420","authenticated-orcid":false,"given":"Aardra","family":"Kachroo","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology, University of Kentucky, Lexington, KY 40546, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huazhen","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology, University of Kentucky, Lexington, KY 40546, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology, University of Kentucky, Lexington, KY 40546, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsushi","family":"Kurokawa","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology, University of Kentucky, Lexington, KY 40546, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep","family":"Kachroo","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology, University of Kentucky, Lexington, KY 40546, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"288","published-online":{"date-parts":[[2022,9,30]]},"reference":[{"key":"2022093009505925700_B1","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1016\/j.jaci.2009.12.980","article-title":"Overview of the immune response","volume":"125","author":"Chaplin","year":"2010","journal-title":"J. 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